Aliases for RBMXL1 Gene
External Ids for RBMXL1 Gene
Previous GeneCards Identifiers for RBMXL1 Gene
This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009]
GeneCards Summary for RBMXL1 Gene
RBMXL1 (RBMX Like 1) is a Protein Coding gene. Diseases associated with RBMXL1 include Autosomal Recessive Nonsyndromic Deafness 32 and Deafness, Autosomal Recessive 1A. Among its related pathways are mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is RBMX.
UniProtKB/Swiss-Prot Summary for RBMXL1 Gene
RNA-binding protein which may be involved in pre-mRNA splicing.