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Aliases for RBM44 Gene

Aliases for RBM44 Gene

  • RNA Binding Motif Protein 44 2 3 5
  • RNA-Binding Motif Protein 44 4

External Ids for RBM44 Gene

Previous GeneCards Identifiers for RBM44 Gene

  • GC02P238373
  • GC02P238707
  • GC02P230499

Summaries for RBM44 Gene

GeneCards Summary for RBM44 Gene

RBM44 (RNA Binding Motif Protein 44) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding.

UniProtKB/Swiss-Prot for RBM44 Gene

  • Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity).

Additional gene information for RBM44 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM44 Gene

Genomics for RBM44 Gene

GeneHancer (GH) Regulatory Elements for RBM44 Gene

Promoters and enhancers for RBM44 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I237798 Promoter 0.5 EPDnew 550.8 +0.7 710 0.1 RBM44 GC02M237806 LRRFIP1
GH02I238283 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 15.5 +489.6 489607 8 HDGF PKNOX1 CLOCK FOXA2 MLX ARNT ARID4B NEUROD1 SIN3A FEZF1 PER2 ENSG00000283635 LOC151174 LOC643387 RBM44 COL6A3 TRAF3IP1 ERFE SCLY PIR48935
GH02I237660 Enhancer 1.3 Ensembl ENCODE dbSUPER 17.4 -135.7 -135675 4.3 PKNOX1 FOXA2 INSM2 KLF17 SIN3A FEZF1 BMI1 ZNF2 RAD21 YY1 RBM44 RAB17 LOC105373958 PRLH RNU6-1140P MLPH LRRFIP1 ENSG00000227107 PIR56300
GH02I237084 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 10.5 -712.0 -711996 2.8 HDGF PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 IRF4 COPS8 ENSG00000227252 LOC93463 RBM44 ENSG00000224844
GH02I237741 Enhancer 1.4 Ensembl ENCODE dbSUPER 14.7 -54.3 -54330 4.1 HDGF FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 ZNF48 YY1 SLC30A9 RBM44 GC02M237763 PIR56300 LRRFIP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RBM44 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RBM44 gene promoter:

Genomic Locations for RBM44 Gene

Genomic Locations for RBM44 Gene
44,759 bases
Plus strand

Genomic View for RBM44 Gene

Genes around RBM44 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM44 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM44 Gene

Proteins for RBM44 Gene

  • Protein details for RBM44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein 44
    Protein Accession:
    Secondary Accessions:
    • A0AUW3

    Protein attributes for RBM44 Gene

    1051 amino acids
    Molecular mass:
    117985 Da
    Quaternary structure:
    • Homodimer. Interacts with TEX14 (By similarity).
    • Sequence=AAI26112.1; Type=Miscellaneous discrepancy; Note=Unlikely splicing event.; Evidence={ECO:0000305}; Sequence=BAC85324.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for RBM44 Gene

Post-translational modifications for RBM44 Gene

No Post-translational modifications

No data available for DME Specific Peptides for RBM44 Gene

Domains & Families for RBM44 Gene

Gene Families for RBM44 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RBM44 Gene

Suggested Antigen Peptide Sequences for RBM44 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBM44: view

No data available for UniProtKB/Swiss-Prot for RBM44 Gene

Function for RBM44 Gene

Molecular function for RBM44 Gene

UniProtKB/Swiss-Prot Function:
Component of intercellular bridges during meiosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells. Not required for fertility (By similarity).

Phenotypes From GWAS Catalog for RBM44 Gene

Gene Ontology (GO) - Molecular Function for RBM44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA --
GO:0042803 protein homodimerization activity ISS --
genes like me logo Genes that share ontologies with RBM44: view

Phenotypes for RBM44 Gene

genes like me logo Genes that share phenotypes with RBM44: view

Animal Models for RBM44 Gene

MGI Knock Outs for RBM44:

Animal Model Products

CRISPR Products

miRNA for RBM44 Gene

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RBM44 Gene

Localization for RBM44 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM44 Gene

Cytoplasm. Note=Detected in the intercellular bridges. {ECO:0000250}.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM44 gene
Compartment Confidence
extracellular 5
nucleus 2
cytosol 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for RBM44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm ISS --
GO:0045171 intercellular bridge ISS --
genes like me logo Genes that share ontologies with RBM44: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for RBM44 Gene

Pathways & Interactions for RBM44 Gene

SuperPathways for RBM44 Gene

No Data Available

Interacting Proteins for RBM44 Gene

Gene Ontology (GO) - Biological Process for RBM44 Gene


No data available for Pathways by source and SIGNOR curated interactions for RBM44 Gene

Drugs & Compounds for RBM44 Gene

No Compound Related Data Available

Transcripts for RBM44 Gene

Unigene Clusters for RBM44 Gene

RNA binding motif protein 44:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM44 Gene

No ASD Table

Relevant External Links for RBM44 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM44 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RBM44 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for RBM44 Gene

This gene is overexpressed in Testis (x16.8).

Protein differential expression in normal tissues from HIPED for RBM44 Gene

This gene is overexpressed in Ovary (35.2) and Testis (32.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RBM44 Gene

Protein tissue co-expression partners for RBM44 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RBM44 Gene:


SOURCE GeneReport for Unigene cluster for RBM44 Gene:

genes like me logo Genes that share expression patterns with RBM44: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for RBM44 Gene

Orthologs for RBM44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RBM44 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RBM44 33 34
  • 98.61 (n)
(Canis familiaris)
Mammalia RBM44 33 34
  • 84.23 (n)
(Bos Taurus)
Mammalia RBM44 34 33
  • 84.23 (n)
(Mus musculus)
Mammalia Rbm44 33 16 34
  • 72.82 (n)
(Rattus norvegicus)
Mammalia Rbm44 33
  • 71.32 (n)
(Ornithorhynchus anatinus)
Mammalia RBM44 34
  • 42 (a)
(Monodelphis domestica)
Mammalia RBM44 34
  • 39 (a)
(Gallus gallus)
Aves RBM44 34
  • 37 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 39 (a)
-- 34
  • 35 (a)
(Danio rerio)
Actinopterygii RBM44 34
  • 19 (a)
Species where no ortholog for RBM44 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RBM44 Gene

Gene Tree for RBM44 (if available)
Gene Tree for RBM44 (if available)

Paralogs for RBM44 Gene

No data available for Paralogs for RBM44 Gene

Variants for RBM44 Gene

Sequence variations from dbSNP and Humsavar for RBM44 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000020053 -- 237,803,485(+) A/T genic_upstream_transcript_variant, intron_variant
rs1000046445 -- 237,823,773(+) TTCTTCT/TTCT downstream_transcript_variant, genic_downstream_transcript_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000122494 -- 237,840,064(+) C/T genic_downstream_transcript_variant, intron_variant
rs1000122606 -- 237,833,594(+) A/G genic_downstream_transcript_variant, intron_variant
rs1000136905 -- 237,796,972(+) T/C upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for RBM44 Gene

Variant ID Type Subtype PubMed ID
nsv519581 CNV loss 19592680
nsv516443 CNV gain+loss 19592680
nsv1073027 CNV deletion 25765185
nsv1000252 CNV loss 25217958
esv3594753 CNV loss 21293372
esv3594752 CNV gain 21293372
esv3594750 CNV gain 21293372
esv3594749 CNV gain 21293372
esv3437644 CNV insertion 20981092
esv3346258 CNV insertion 20981092
esv3303771 CNV mobile element insertion 20981092
esv2760579 CNV gain 21179565
esv2678433 CNV deletion 23128226

Variation tolerance for RBM44 Gene

Residual Variation Intolerance Score: 61.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.67; 65.84% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RBM44 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM44 Gene

Disorders for RBM44 Gene

Additional Disease Information for RBM44

No disorders were found for RBM44 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM44 Gene

Publications for RBM44 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L … Andersson-Svahn H (Molecular & cellular proteomics : MCP 2008) 3 58
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 58
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58

Products for RBM44 Gene

Sources for RBM44 Gene

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