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Aliases for RBM33 Gene

Aliases for RBM33 Gene

  • RNA Binding Motif Protein 33 2 3 5
  • RNA-Binding Protein 33 3 4
  • Proline-Rich Protein 8 3 4
  • Proline Rich 8 2 3
  • PRR8 3 4
  • Hypothetical Protein MGC20460 3
  • RNA-Binding Motif Protein 33 4

External Ids for RBM33 Gene

Previous HGNC Symbols for RBM33 Gene

  • PRR8

Previous GeneCards Identifiers for RBM33 Gene

  • GC07P155039
  • GC07P155232
  • GC07P155133
  • GC07P155437
  • GC07P149167

Summaries for RBM33 Gene

GeneCards Summary for RBM33 Gene

RBM33 (RNA Binding Motif Protein 33) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding.

Gene Wiki entry for RBM33 Gene

Additional gene information for RBM33 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM33 Gene

Genomics for RBM33 Gene

GeneHancer (GH) Regulatory Elements for RBM33 Gene

Promoters and enhancers for RBM33 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J155643 Promoter/Enhancer 1.5 Ensembl ENCODE 661.2 +0.4 434 3.8 ZNF652 ELF3 ZFX MNT NKRF POLR2A MLLT1 GTF2F1 CSDE1 ZNF687 RBM33 ENSG00000216895 ENSG00000283128 LOC100506302 PAXIP1 PAXIP1-AS2 ENSG00000273183 PAXIP1-AS1
GH07J155746 Promoter/Enhancer 1.3 EPDnew Ensembl dbSUPER 600.2 +102.0 102028 0.6 CREM ZBED1 EED RUNX3 JUNB IRF4 BATF ATF2 SRF RBM33 PIR49030 ENSG00000216895
GH07J155917 Enhancer 1.2 Ensembl ENCODE 53.5 +274.3 274259 3.3 ZNF473 ELF3 RERE ZSCAN21 CDC5L MYC TFE3 ZBTB7A SP1 PPARG PAXIP1-AS2 RBM33 PAXIP1 ENSG00000273183 PAXIP1-AS1 RNF32 LOC389602 GC07M155822
GH07J155295 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 12 -345.7 -345676 6.1 SP1 ZFX CBFA2T2 NKRF MLLT1 POLR2A CSDE1 ZNF687 FOS MAFK ENSG00000273117 INSIG1 LOC105375591 RBM33 PAXIP1 GC07P155307
GH07J156638 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 10.7 +995.7 995729 4 ZFX NKRF MLLT1 POLR2A GTF2F1 CSDE1 ZNF687 NCOA6 YY1 TRIM24 LINC01006 RNF32 PIR39241 GC07M156641 NOM1 UBE3C RBM33 LMBR1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RBM33 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RBM33 gene promoter:
  • FOXF2
  • HNF-3beta
  • Roaz

Genomic Locations for RBM33 Gene

Genomic Locations for RBM33 Gene
137,035 bases
Plus strand
137,035 bases
Plus strand

Genomic View for RBM33 Gene

Genes around RBM33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM33 Gene

Proteins for RBM33 Gene

  • Protein details for RBM33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein 33
    Protein Accession:
    Secondary Accessions:
    • A4D244
    • B5MC24
    • Q52LF5
    • Q75LN9
    • Q75ML5
    • Q9NSV0

    Protein attributes for RBM33 Gene

    1170 amino acids
    Molecular mass:
    129986 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH93947.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH93949.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAS01989.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAS02026.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAS07551.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB70894.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=EAL23911.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=EAL23912.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=EAX04539.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for RBM33 Gene


neXtProt entry for RBM33 Gene

Post-translational modifications for RBM33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RBM33 Gene

Domains & Families for RBM33 Gene

Gene Families for RBM33 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RBM33 Gene

Suggested Antigen Peptide Sequences for RBM33 Gene

GenScript: Design optimal peptide antigens:
  • RNA-binding motif protein 33 (RBM33_HUMAN)

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBM33: view

No data available for UniProtKB/Swiss-Prot for RBM33 Gene

Function for RBM33 Gene

Phenotypes From GWAS Catalog for RBM33 Gene

Gene Ontology (GO) - Molecular Function for RBM33 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA,HDA 22658674
genes like me logo Genes that share ontologies with RBM33: view
genes like me logo Genes that share phenotypes with RBM33: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for RBM33 - Now 50% OFF >
  • * RBM33 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * RBM33 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM33 Gene

Localization for RBM33 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM33 gene
Compartment Confidence
nucleus 4
cytosol 3
plasma membrane 2
cytoskeleton 2

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RBM33 Gene

Pathways & Interactions for RBM33 Gene

PathCards logo

SuperPathways for RBM33 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM33 Gene


No data available for Pathways by source and SIGNOR curated interactions for RBM33 Gene

Drugs & Compounds for RBM33 Gene

No Compound Related Data Available

Transcripts for RBM33 Gene

mRNA/cDNA for RBM33 Gene

Unigene Clusters for RBM33 Gene

RNA binding motif protein 33:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for RBM33 - Now 50% OFF >
  • * RBM33 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * RBM33 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for RBM33 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b
SP2: -

Relevant External Links for RBM33 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM33 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RBM33 Gene

Protein differential expression in normal tissues from HIPED for RBM33 Gene

This gene is overexpressed in Cervix (21.0), Peripheral blood mononuclear cells (13.1), and CD8 Tcells (6.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RBM33 Gene

Protein tissue co-expression partners for RBM33 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of RBM33 Gene:


SOURCE GeneReport for Unigene cluster for RBM33 Gene:


Evidence on tissue expression from TISSUES for RBM33 Gene

  • Nervous system(4.7)
  • Liver(4.2)
genes like me logo Genes that share expression patterns with RBM33: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RBM33 Gene

Orthologs for RBM33 Gene

This gene was present in the common ancestor of chordates.

Orthologs for RBM33 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RBM33 35 34
  • 98.85 (n)
(Canis familiaris)
Mammalia RBM33 35
  • 88 (a)
(Mus musculus)
Mammalia Rbm33 35
  • 83 (a)
(Bos Taurus)
Mammalia RBM33 35
  • 82 (a)
(Monodelphis domestica)
Mammalia RBM33 35
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia RBM33 35
  • 76 (a)
(Gallus gallus)
Aves RBM33 35
  • 72 (a)
(Anolis carolinensis)
Reptilia RBM33 35
  • 63 (a)
(Danio rerio)
Actinopterygii RBM33 (1 of 2) 35
  • 39 (a)
RBM33 (2 of 2) 35
  • 24 (a)
Species where no ortholog for RBM33 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for RBM33 Gene

Gene Tree for RBM33 (if available)
Gene Tree for RBM33 (if available)
Evolutionary constrained regions (ECRs) for RBM33: view image

Paralogs for RBM33 Gene

No data available for Paralogs for RBM33 Gene

Variants for RBM33 Gene

Sequence variations from dbSNP and Humsavar for RBM33 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1000001590 -- 155,726,821(+) G/A intron_variant
rs1000073813 -- 155,672,669(+) T/C intron_variant
rs1000079528 -- 155,771,791(+) G/T intron_variant
rs1000088544 -- 155,666,884(+) TTTTTT/TTTTTTT intron_variant
rs1000142149 -- 155,671,231(+) A/G/T intron_variant

Structural Variations from Database of Genomic Variants (DGV) for RBM33 Gene

Variant ID Type Subtype PubMed ID
dgv6767n100 CNV gain 25217958
esv2735590 CNV deletion 23290073
esv274974 CNV loss 21479260
esv3572346 CNV loss 25503493
esv3576492 CNV gain 25503493
esv3615635 CNV loss 21293372
esv997138 CNV insertion 20482838
nsv1021843 CNV loss 25217958
nsv1032585 CNV gain 25217958
nsv1033092 CNV loss 25217958
nsv1109931 CNV deletion 24896259
nsv1134906 CNV tandem duplication 24896259
nsv1140870 CNV deletion 24896259
nsv365283 CNV deletion 16902084
nsv480477 CNV novel sequence insertion 20440878
nsv509227 CNV insertion 20534489
nsv951661 CNV duplication 24416366

Variation tolerance for RBM33 Gene

Residual Variation Intolerance Score: 11.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.65; 82.82% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RBM33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RBM33 Gene

Disorders for RBM33 Gene

Additional Disease Information for RBM33

No disorders were found for RBM33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM33 Gene

Publications for RBM33 Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer SW … Tsui LC (Science (New York, N.Y.) 2003) 3 4 58
  4. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 3 4 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for RBM33 Gene

Sources for RBM33 Gene

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