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Aliases for RBM24 Gene

Aliases for RBM24 Gene

  • RNA Binding Motif Protein 24 2 3 5
  • RNA-Binding Region (RNP1, RRM) Containing 6 2 3
  • RNA-Binding Region-Containing Protein 6 3 4
  • RNPC6 3 4
  • RNA-Binding Motif Protein 24 4
  • RNA-Binding Protein 24 3
  • DJ259A10.1 3

External Ids for RBM24 Gene

Previous HGNC Symbols for RBM24 Gene

  • RNPC6

Previous GeneCards Identifiers for RBM24 Gene

  • GC06P017390
  • GC06P017391

Summaries for RBM24 Gene

GeneCards Summary for RBM24 Gene

RBM24 (RNA Binding Motif Protein 24) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and mRNA 3-UTR binding. An important paralog of this gene is RBM38.

UniProtKB/Swiss-Prot for RBM24 Gene

  • Plays a role in myogenic differentiation by regulating MYOG levels. Binds to the 3-UTR of MYOG mRNA and regulates its stability.

Additional gene information for RBM24 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RBM24 Gene

Genomics for RBM24 Gene

GeneHancer (GH) Regulatory Elements for RBM24 Gene

Promoters and enhancers for RBM24 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I017276 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 567.9 -1.0 -1044 7.6 ZFP64 SIN3A RAD21 GLIS2 SCRT2 FOS CEBPB MAFF ZNF341 KDM1A RBM24 CAP2 STMND1 LOC101928463
GH06I017311 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 13.3 +30.7 30662 2 FOXA2 MLX ARID4B DMAP1 YY1 ZNF766 PAF1 SP5 ZHX2 MXD4 RBM24 CAP2 GC06P017304 LOC100421092
GH06I017304 Enhancer 0.9 ENCODE dbSUPER 11.9 +24.2 24208 1.3 MEIS2 SOX13 TEAD4 TAL1 ZNF644 ZBTB40 TCF12 ZNF766 NCOR1 VEZF1 GC06P017304 RBM24 CAP2 LOC100421092
GH06I017211 Enhancer 0.4 Ensembl ENCODE 11 -68.7 -68693 1.5 RBM24 LOC101928463 GC06P016871
GH06I017200 Enhancer 0.4 ENCODE 11 -80.7 -80731 0.1 CTCF BACH1 RBM24 LOC101928463 GC06P016871
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around RBM24 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the RBM24 gene promoter:

Genomic Locations for RBM24 Gene

Genomic Locations for RBM24 Gene
12,530 bases
Plus strand

Genomic View for RBM24 Gene

Genes around RBM24 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RBM24 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RBM24 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for RBM24 Gene

Proteins for RBM24 Gene

  • Protein details for RBM24 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    RNA-binding protein 24
    Protein Accession:
    Secondary Accessions:
    • E9PAY4
    • Q6QDA4
    • Q8N9D3
    • Q96NI3

    Protein attributes for RBM24 Gene

    236 amino acids
    Molecular mass:
    24776 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC04474.1; Type=Miscellaneous discrepancy; Note=Unlikely isoform. Aberrant splice sites.; Evidence={ECO:0000305};

    Alternative splice isoforms for RBM24 Gene


neXtProt entry for RBM24 Gene

Post-translational modifications for RBM24 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for RBM24 Gene

Domains & Families for RBM24 Gene

Gene Families for RBM24 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for RBM24 Gene

Suggested Antigen Peptide Sequences for RBM24 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with RBM24: view

No data available for UniProtKB/Swiss-Prot for RBM24 Gene

Function for RBM24 Gene

Molecular function for RBM24 Gene

UniProtKB/Swiss-Prot Function:
Plays a role in myogenic differentiation by regulating MYOG levels. Binds to the 3-UTR of MYOG mRNA and regulates its stability.

Phenotypes From GWAS Catalog for RBM24 Gene

Gene Ontology (GO) - Molecular Function for RBM24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA --
GO:0003730 mRNA 3-UTR binding ISS --
genes like me logo Genes that share ontologies with RBM24: view
genes like me logo Genes that share phenotypes with RBM24: view

Animal Model Products

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RBM24 Gene

Localization for RBM24 Gene

Subcellular locations from UniProtKB/Swiss-Prot for RBM24 Gene

Nucleus. Cytoplasm.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RBM24 gene
Compartment Confidence
cytosol 5
nucleus 4
mitochondrion 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (4)
  • Nucleoplasm (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RBM24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with RBM24: view

Pathways & Interactions for RBM24 Gene

SuperPathways for RBM24 Gene

No Data Available

Gene Ontology (GO) - Biological Process for RBM24 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0010830 regulation of myotube differentiation ISS --
GO:0030154 cell differentiation IEA --
GO:0043488 regulation of mRNA stability ISS --
genes like me logo Genes that share ontologies with RBM24: view

No data available for Pathways by source and SIGNOR curated interactions for RBM24 Gene

Drugs & Compounds for RBM24 Gene

No Compound Related Data Available

Transcripts for RBM24 Gene

Unigene Clusters for RBM24 Gene

RNA binding motif protein 24:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RBM24 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b
SP1: - -
SP2: - - -
SP3: - -
SP4: -

Relevant External Links for RBM24 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for RBM24 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for RBM24 Gene

mRNA differential expression in normal tissues according to GTEx for RBM24 Gene

This gene is overexpressed in Muscle - Skeletal (x20.0), Heart - Atrial Appendage (x8.6), and Heart - Left Ventricle (x7.7).

Protein differential expression in normal tissues from HIPED for RBM24 Gene

This gene is overexpressed in Bone (44.8) and Heart (22.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for RBM24 Gene

Protein tissue co-expression partners for RBM24 Gene

NURSA nuclear receptor signaling pathways regulating expression of RBM24 Gene:


SOURCE GeneReport for Unigene cluster for RBM24 Gene:


Evidence on tissue expression from TISSUES for RBM24 Gene

  • Nervous system(4.2)
  • Muscle(3.4)
  • Heart(3)
genes like me logo Genes that share expression patterns with RBM24: view

No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RBM24 Gene

Orthologs for RBM24 Gene

This gene was present in the common ancestor of animals.

Orthologs for RBM24 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia RBM24 33 34
  • 99.86 (n)
(Ornithorhynchus anatinus)
Mammalia RBM24 34
  • 93 (a)
(Canis familiaris)
Mammalia RBM24 33 34
  • 92.53 (n)
(Bos Taurus)
Mammalia RBM24 33 34
  • 90.68 (n)
(Monodelphis domestica)
Mammalia RBM24 34
  • 90 (a)
(Mus musculus)
Mammalia Rbm24 33 16 34
  • 88.7 (n)
(Rattus norvegicus)
Mammalia Rbm24 33
  • 88.14 (n)
(Gallus gallus)
Aves RBM24 34
  • 96 (a)
(Anolis carolinensis)
Reptilia RBM24 34
  • 98 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia rbm24 33
  • 80.24 (n)
MGC75808 33
African clawed frog
(Xenopus laevis)
Amphibia MGC52530 33
(Danio rerio)
Actinopterygii rbm24a 33 34
  • 71.76 (n)
(Caenorhabditis elegans)
Secernentea sup-12 34
  • 44 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10652 34
  • 50 (a)
Species where no ortholog for RBM24 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for RBM24 Gene

Gene Tree for RBM24 (if available)
Gene Tree for RBM24 (if available)

Paralogs for RBM24 Gene

Paralogs for RBM24 Gene

(2) SIMAP similar genes for RBM24 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with RBM24: view

Variants for RBM24 Gene

Sequence variations from dbSNP and Humsavar for RBM24 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000044571 -- 17,282,621(+) A/C genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000099957 -- 17,282,037(+) G/A/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant
rs1000213047 -- 17,285,404(+) A/T intron_variant
rs1000330230 -- 17,288,012(+) A/T intron_variant
rs1000532626 -- 17,283,916(+) A/T genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant

Variation tolerance for RBM24 Gene

Residual Variation Intolerance Score: 50% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.07; 50.69% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RBM24 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for RBM24 Gene

Disorders for RBM24 Gene

Additional Disease Information for RBM24

No disorders were found for RBM24 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RBM24 Gene

Publications for RBM24 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall AJ … Beck S (Nature 2003) 3 4 58
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  5. RBM24 promotes U1 snRNP recognition of the mutated 5' splice site in the IKBKAP gene of familial dysautonomia. (PMID: 28592461) Ohe K … Hagiwara M (RNA (New York, N.Y.) 2017) 3 58

Products for RBM24 Gene

Sources for RBM24 Gene

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