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This gene encodes an RNA binding protein. The encoded protein may play a role in cell division and may be involved in pre-mRNA splicing. Related pseudogenes exist on chromosomes 6, 7, 9, 13, 16, 18, and X. [provided by RefSeq, Mar 2009]
RBM22 (RNA Binding Motif Protein 22) is a Protein Coding gene. Among its related pathways are Gene Expression and mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and nucleotide binding.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003676 | nucleic acid binding | IEA | -- |
GO:0003723 | RNA binding | IEA,HDA | 22658674 |
GO:0005515 | protein binding | IPI | 25416956 |
GO:0017070 | U6 snRNA binding | IDA | 22246180 |
GO:0036002 | pre-mRNA binding | IBA,IDA | 22246180 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000974 | Prp19 complex | IBA | 21873635 |
GO:0005634 | nucleus | IEA,IDA | 17045351 |
GO:0005654 | nucleoplasm | IDA,TAS | -- |
GO:0005681 | spliceosomal complex | IEA | -- |
GO:0005737 | cytoplasm | IEA,IDA | 21122810 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | mRNA Splicing - Major Pathway |
.79
|
.47
|
2 | Gene Expression |
.48
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000398 | mRNA splicing, via spliceosome | IEA,TAS | -- |
GO:0006397 | mRNA processing | IEA | -- |
GO:0008380 | RNA splicing | IEA | -- |
GO:0033120 | positive regulation of RNA splicing | IDA | 22246180 |
GO:0035690 | cellular response to drug | IDA | 21122810 |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||
SP4: |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RBM22 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Platypus (Ornithorhynchus anatinus) |
Mammalia | RBM22 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RBM22 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RBM22 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rbm22 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rbm22 30 |
|
||
Chicken (Gallus gallus) |
Aves | RBM22 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RBM22 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rbm22 30 |
|
||
MGC76229 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | cg14641-prov 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | RBM22 (3 of 3) 31 |
|
OneToMany | |
rbm22 30 31 31 |
|
OneToMany | |||
wufc62e03 30 |
|
||||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004509 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG14641 30 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | T11G6.8 30 31 |
|
OneToOne | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ECM2 31 33 |
|
OneToOne | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT1G07360 30 |
|
||
Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.1512 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os07g0281000 30 |
|
||
Os.14314 30 |
|
||||
Barley (Hordeum vulgare) |
Liliopsida | Hv.2670 30 |
|
||
Wheat (Triticum aestivum) |
Liliopsida | Ta.14515 30 |
|
||
Corn (Zea mays) |
Liliopsida | Zm.4129 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.8471 31 |
|
OneToOne | |
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.2969 30 |
|
SNP ID | Clinical significance and condition | Chr 05 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
773937 | Benign: not provided | 150,691,844(-) | G/C | SYNONYMOUS_VARIANT |
No disorders were found for RBM22 Gene.