External Ids for RBKS Gene
Previous GeneCards Identifiers for RBKS Gene
This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
GeneCards Summary for RBKS Gene
RBKS (Ribokinase) is a Protein Coding gene. Diseases associated with RBKS include Roberts-Sc Phocomelia Syndrome and Cyclosporiasis. Among its related pathways are Pentose phosphate pathway and Metabolism. Gene Ontology (GO) annotations related to this gene include ribokinase activity. An important paralog of this gene is ADK.
UniProtKB/Swiss-Prot Summary for RBKS Gene
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.