Aliases for RASSF6 Gene
External Ids for RASSF6 Gene
Previous GeneCards Identifiers for RASSF6 Gene
This gene encodes a member of the Ras-association domain family (RASSF). Members of this family form the core of a highly conserved tumor suppressor network, the Salvador-Warts-Hippo (SWH) pathway. The protein encoded by this gene is a Ras effector protein that induces apoptosis. A genomic region containing this gene has been linked to susceptibility to viral bronchiolitis. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
GeneCards Summary for RASSF6 Gene
RASSF6 (Ras Association Domain Family Member 6) is a Protein Coding gene. Diseases associated with RASSF6 include Bronchiolitis and Hyperlucent Lung. Among its related pathways are Hippo signaling pathway and Hippo signaling pathway - multiple species. An important paralog of this gene is RASSF4.
UniProtKB/Swiss-Prot Summary for RASSF6 Gene
Involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. May act as a Ras effector protein. May suppress the serum-induced basal levels of NF-kappa-B (By similarity).