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The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008] See more...
Aliases for RASSF4 Gene
Aliases for RASSF4 Gene
External Ids for RASSF4 Gene
- HGNC: 20793
- Entrez Gene: 83937
- Ensembl: ENSG00000107551
- OMIM: 610559
- UniProtKB: Q9H2L5
Previous GeneCards Identifiers for RASSF4 Gene
- GC10P045230
- GC10P044739
- GC10P044775
- GC10P045454
- GC10P041979
Summaries for RASSF4 Gene
-
The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008]
GeneCards Summary for RASSF4 Gene
RASSF4 (Ras Association Domain Family Member 4) is a Protein Coding gene. Among its related pathways are Hippo signaling pathway - multiple species. An important paralog of this gene is RASSF2.
UniProtKB/Swiss-Prot Summary for RASSF4 Gene
-
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Additional gene information for RASSF4 Gene
- HGNC(20793)
- Entrez Gene(83937)
- Ensembl(ENSG00000107551)
- OMIM(610559)
- UniProtKB(Q9H2L5)
- Open Targets Platform(ENSG00000107551)
- Search for RASSF4 at DataMed
- Search for RASSF4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RASSF4 Gene
Genomics for RASSF4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RASSF4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RASSF4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RASSF4
- Top Transcription factor binding sites by QIAGEN in the RASSF4 gene promoter:
-
- AREB6
- Bach2
- HNF-1
- HNF-1A
- Pax-5
- RFX1
- SRF
- SRF (504 AA)
- SRY
- ZID
Genomic Locations for RASSF4 Gene
Genomic Locations for RASSF4 Gene
- chr10:44,959,407-44,995,891
- (GRCh38/hg38)
- Size:
- 36,485 bases
- Orientation:
- Plus strand
- chr10:45,454,855-45,491,339
- (GRCh37/hg19)
- Size:
- 36,485 bases
- Orientation:
- Plus strand
Genomic View for RASSF4 Gene
Genes around RASSF4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q11.21 by HGNC
- 10q11.21 by Entrez Gene
- 10q11.21 by Ensembl
RASSF4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RASSF4 Gene
Proteins for RASSF4 Gene
-
Protein details for RASSF4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H2L5-RASF4_HUMAN
- Recommended name:
- Ras association domain-containing protein 4
- Protein Accession:
- Q9H2L5
- Q86WH5
- Q86WH6
- Q86WH7
- Q8N5A9
- Q8TCK6
Protein attributes for RASSF4 Gene
- Size:
- 321 amino acids
- Molecular mass:
- 36748 Da
- Quaternary structure:
-
- Interacts directly with activated KRAS in a GTP-dependent manner.
Protein Expression for RASSF4 Gene
Post-translational modifications for RASSF4 Gene
Other Protein References for RASSF4 Gene
Antibody Products
- G Biosciences Immunotag™ RASSF4 Antibody
- Creative Diagnostics Anti-RASSF4 monoclonal antibody
- Creative Biolabs Mouse Anti-RASSF4 Recombinant Antibody (1D5)
-
Custom Antibody ServicesOriGene Antibodies for RASSF4
- Novus Biologicals Antibodies for RASSF4
- Invitrogen Antibodies for RASSF4 (AFLGC-RASSF4)
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for RASSF4
- Origene Custom Protein Services for RASSF4
- antibodies-online: Show 5 available RASSF4 Proteins ranked by validation data
- Compare Top RASSF4 Proteins
-
Quality Products:
-
Signalway Proteins for RASSF4
-
Abcam proteins for RASSF4
No data available for DME Specific Peptides for RASSF4 Gene
Domains & Families for RASSF4 Gene
Gene Families for RASSF4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for RASSF4 Gene
Suggested Antigen Peptide Sequences for RASSF4 Gene
- GenScript: Design optimal peptide antigens:
-
- Ras association (RalGDS/AF-6) domain family member 4 (Q5T737_HUMAN)
- Ras association domain-containing protein 4 (RASF4_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RASSF4 Gene
Function for RASSF4 Gene
Molecular function for RASSF4 Gene
- UniProtKB/Swiss-Prot Function:
- Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.
Phenotypes From GWAS Catalog for RASSF4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 20562859 |
Phenotypes for RASSF4 Gene
Animal Model Products
-
Taconic Biosciences Mouse Models for RASSF4
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RASSF4 - Select products 50% OFF >
- * RASSF4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RASSF4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASSF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for RASSF4
miRNA for RASSF4 Gene
- miRTarBase miRNAs that target RASSF4
-
- mmu-miR-541-5p (MIRT008381)
- mmu-miR-17-5p (MIRT010024)
- mmu-miR-324-3p (MIRT010962)
- mmu-miR-1190 (MIRT603492)
- mmu-miR-883a-5p (MIRT603494)
- hsa-miR-6876-3p (MIRT607785)
- hsa-miR-626 (MIRT607786)
- hsa-miR-8485 (MIRT607787)
- hsa-miR-6787-3p (MIRT609073)
- hsa-miR-4291 (MIRT631491)
- hsa-miR-761 (MIRT631492)
- hsa-miR-3619-5p (MIRT631493)
- hsa-miR-214-3p (MIRT631494)
- hsa-miR-922 (MIRT631495)
- hsa-miR-4312 (MIRT635328)
- hsa-miR-6882-3p (MIRT635329)
- hsa-miR-6754-5p (MIRT635330)
- hsa-miR-4441 (MIRT635331)
- hsa-miR-4270 (MIRT635332)
- hsa-miR-6510-5p (MIRT635333)
- hsa-miR-1301-3p (MIRT737254)
- hsa-miR-5047 (MIRT749570)
- hsa-miR-578 (MIRT751498)
- hsa-miR-7156-3p (MIRT759273)
- hsa-miR-8066 (MIRT760071)
- hsa-miR-8070 (MIRT760086)
- hsa-miR-147b (MIRT790120)
- hsa-miR-203b-5p (MIRT790161)
- hsa-miR-24-3p (MIRT790198)
- hsa-miR-2682-5p (MIRT790200)
- hsa-miR-34b-5p (MIRT790300)
- hsa-miR-3607-5p (MIRT790308)
- hsa-miR-3714 (MIRT790346)
- hsa-miR-4284 (MIRT790408)
- hsa-miR-4474-3p (MIRT790473)
- hsa-miR-449c-5p (MIRT790501)
- hsa-miR-4709-5p (MIRT790580)
- hsa-miR-548an (MIRT790738)
- hsa-miR-548au-3p (MIRT790742)
- hsa-miR-644a (MIRT790845)
- hsa-miR-6718-5p (MIRT790884)
- hsa-miR-6847-3p (MIRT791020)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASSF4
- Browse OriGene Inhibitory RNA Products For RASSF4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RASSF4
Clone Products
- Applied Biological Materials (abm): Clones for RASSF4 - Select products 50% OFF >
- * RASSF4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RASSF4
- Addgene plasmids for RASSF4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASSF4
Cell Line Products
-
Horizon Cell Lines for RASSF4
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RASSF4 Gene
Localization for RASSF4 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
- Cell Junctions (2)
- Nucleoli (2)
- Nucleoplasm (2)
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for RASSF4 Gene
Pathways & Interactions for RASSF4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Hippo signaling pathway - multiple species | ||
Pathways by source for RASSF4 Gene
1 KEGG pathway for RASSF4 Gene
Interacting Proteins for RASSF4 Gene
Selected Interacting proteins:
Q9H2L5-RASF4_HUMAN
ENSP00000339692
for RASSF4 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RASSF4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007049 | cell cycle | IEA | -- |
| GO:0007165 | signal transduction | IEA | -- |
No data available for SIGNOR curated interactions for RASSF4 Gene
Drugs & Compounds for RASSF4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for RASSF4 Gene
mRNA/cDNA for RASSF4 Gene
- 2 REFSEQ mRNAs :
- 13 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000340258 3631 nts (view in UCSC)
- ENST00000427758 528 nts (view in UCSC)
- ENST00000428466 435 nts (view in UCSC)
- ENST00000462822 354 nts (view in UCSC)
- ENST00000465735 2207 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RASSF4 - Select products 50% OFF >
- * RASSF4 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RASSF4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASSF4
-
Santa Cruz Biotechnology (SCBT) CRISPR for RASSF4
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASSF4
- Browse OriGene Inhibitory RNA Products For RASSF4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RASSF4
Clone Products
- Applied Biological Materials (abm): Clones for RASSF4 - Select products 50% OFF >
- * RASSF4 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RASSF4
- Addgene plasmids for RASSF4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASSF4
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8a | · | 8b | · | 8c | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP14: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP19: |
| ExUns: | 12c | ^ | 13a | · | 13b | · | 13c | ^ | 14a | · | 14b | · | 14c | · | 14d | ^ | 15a | · | 15b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||
| SP2: | - | - | |||||||||||||||||
| SP3: | - | - | |||||||||||||||||
| SP4: | - | - | |||||||||||||||||
| SP5: | - | - | |||||||||||||||||
| SP6: | |||||||||||||||||||
| SP7: | |||||||||||||||||||
| SP8: | |||||||||||||||||||
| SP9: | - | - | |||||||||||||||||
| SP10: | |||||||||||||||||||
| SP11: | |||||||||||||||||||
| SP12: | |||||||||||||||||||
| SP13: | |||||||||||||||||||
| SP14: | |||||||||||||||||||
| SP15: | - | - | |||||||||||||||||
| SP16: | - | ||||||||||||||||||
| SP17: | |||||||||||||||||||
| SP18: | - | ||||||||||||||||||
| SP19: | - |
Relevant External Links for RASSF4 Gene
- GeneLoc Exon Structure for
- RASSF4
Expression for RASSF4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Choroid Plexus Progenitor Cells Choroid Plexus
- Medulla Oblongata
- Cerebral Cortex
- Neural Tube (Nervous System)
-
Blood (Hematopoietic System)
- Monocytes Peripheral Blood
- Eye (Sensory Organs)
-
Spleen (Hematopoietic System)
-
Lung (Respiratory System)
-
Adipose (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for RASSF4 Gene
This gene is overexpressed in Kidney - Cortex (x4.4).
This gene is overexpressed in Fetal Brain (35.3), Spleen (18.7), and NK cells (12.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RASSF4 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RASSF4
SOURCE GeneReport for Unigene cluster for RASSF4 Gene:
Hs.522895mRNA Expression by UniProt/SwissProt for RASSF4 Gene:
Q9H2L5-RASF4_HUMAN
Tissue specificity:
Widely expressed. Frequently down-regulated in tumor cell lines.
Evidence on tissue expression from TISSUES for RASSF4 Gene
- Lymph node(4.3)
- Adrenal gland(4.2)
- Skin(4.1)
- Nervous system(3.9)
Primer Products
-
OriGene qPCR primer pairs for RASSF4
-
OriGene qPCR primer pairs and template standards for RASSF4
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for RASSF4 Gene
Orthologs for RASSF4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RASSF4 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RASSF4 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Cow (Bos Taurus) |
Mammalia | RASSF4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rassf4 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rassf4 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | RASSF4 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rassf4 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rassf4 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000149 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Rassf 30 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for RASSF4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RASSF4 Gene
- ENSEMBL:
- Gene Tree for RASSF4 (if available)
- TreeFam:
- Gene Tree for RASSF4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RASSF4: view image
Paralogs for RASSF4 Gene
Variants for RASSF4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RASSF4 Gene
| SNP ID | Clinical significance and condition | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 716157 | Benign: not provided | 44,984,902(+) | G/A | MISSENSE_VARIANT | |
| 727419 | Likely Benign: not provided | 44,970,223(+) | G/A | SYNONYMOUS_VARIANT | |
| 780862 | Benign: not provided | 44,984,028(+) | G/T | MISSENSE_VARIANT | |
| 781196 | Likely Benign: not provided | 44,984,908(+) | G/A | MISSENSE_VARIANT | |
| 786154 | Benign: not provided | 44,977,730(+) | T/C | MISSENSE_VARIANT,INTRON_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3576560 | CNV | gain | 25503493 |
| esv3578790 | CNV | loss | 25503493 |
| esv3623077 | CNV | loss | 21293372 |
| esv3623079 | CNV | loss | 21293372 |
| esv3623080 | CNV | gain | 21293372 |
| nsv1035235 | CNV | loss | 25217958 |
| nsv526734 | CNV | loss | 19592680 |
| nsv831845 | CNV | gain | 17160897 |
| nsv831846 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
99.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.59;
78.06% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RASSF4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RASSF4
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RASSF4 Gene
Disorders for RASSF4 Gene
Additional Disease Information for RASSF4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for RASSF4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RASSF4 Gene
Publications for RASSF4 Gene
- Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease. (PMID: 17373700) Morgan AR … Williams J (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007) 3 41
- A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A … Goate A (American journal of human genetics 2006) 3 41
- The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P … Rogers J (Nature 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family. (PMID: 15574778) Eckfeld K … Clark GJ (Cancer research 2004) 3 4
ExternalLinks
Products for RASSF4 Gene
- Custom Antibody ServicesOriGene Antibodies for RASSF4
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for RASSF4
- Origene Custom Protein Services for RASSF4
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASSF4
- Browse OriGene Inhibitory RNA Products For RASSF4
- OriGene qPCR primer pairs for RASSF4
- OriGene qPCR primer pairs and template standards for RASSF4
- OriGene CRISPR knockouts for RASSF4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RASSF4
- Sino Biological Human cDNA Clone for RASSF4
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RASSF4
- Novus Biologicals proteins and lysates for RASSF4
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
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- Abcam proteins for RASSF4
- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
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- Taconic Biosciences Mouse Models for RASSF4
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for RASSF4 (AFLGC-RASSF4)
- VectorBuilder Custom and pre-made DNA vectors for RASSF4 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RASSF4 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RASSF4 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RASSF4 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RASSF4
- Addgene plasmids for RASSF4
- antibodies-online: Show 10 available RASSF4 Antibodies ranked by validation data
- Compare Top RASSF4 Antibodies
- antibodies-online: Search results for available RASSF4 related products ranked by validation data
- antibodies-online: Show 5 available RASSF4 Proteins ranked by validation data
- Compare Top RASSF4 Proteins
- Quality Products:
- Horizon Cell Lines for RASSF4
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASSF4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASSF4
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RASSF4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RASSF4
- Signalway Proteins for RASSF4
Sources for RASSF4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB