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RASIP1 (Ras Interacting Protein 1) is a Protein Coding gene. Diseases associated with RASIP1 include Peroxisomal Acyl-Coa Oxidase Deficiency and Cerebral Cavernous Malformations. An important paralog of this gene is RADIL.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 26780829 |
GO:0042803 | protein homodimerization activity | IDA | 26780829 |
GO:0051020 | GTPase binding | IPI | 26780829 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA | -- |
GO:0005794 | Golgi apparatus | IEA | -- |
GO:0005795 | Golgi stack | IEA | -- |
GO:0005911 | cell-cell junction | IMP | 26780829 |
GO:0032991 | protein-containing complex | IDA | 26780829 |
Symbol | External ID(s) | Details |
---|---|---|
BAG3 | ||
CDC42 | ||
ENSG00000272822 | ||
HNRNPD | ||
HRAS |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001525 | angiogenesis | ISS | -- |
GO:0001570 | vasculogenesis | IEA,ISS | -- |
GO:0007165 | signal transduction | IEA | -- |
GO:0010507 | negative regulation of autophagy | IMP | 22354037 |
GO:0033625 | positive regulation of integrin activation | IMP | 26780829 |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Guanosine triphosphate | Experimental | Pharma | 0 |
ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | - | - | |||||||||||||||||||||||||||
SP5: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RASIP1 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RASIP1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RASIP1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rasip1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Rasip1 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | RASIP1 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RASIP1 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RASIP1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rasip1 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC100151130 30 |
|
||
rasip1 31 |
|
OneToOne | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs2287922 | - | p.Arg601Cys |
Disorder | Aliases | PubMed IDs |
---|---|---|
peroxisomal acyl-coa oxidase deficiency |
|
|
cerebral cavernous malformations |
|
|
sotos syndrome 1 |
|
|