Aliases for RASGRP3 Gene
External Ids for RASGRP3 Gene
Previous GeneCards Identifiers for RASGRP3 Gene
The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers. [provided by RefSeq, Mar 2017]
GeneCards Summary for RASGRP3 Gene
RASGRP3 (RAS Guanyl Releasing Protein 3) is a Protein Coding gene. Diseases associated with RASGRP3 include Bleeding Disorder, Platelet-Type, 18 and Systemic Lupus Erythematosus. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include calcium ion binding and GTPase activator activity. An important paralog of this gene is RASGRP1.
UniProtKB/Swiss-Prot Summary for RASGRP3 Gene
Guanine nucleotide exchange factor (GEF) for Ras and Rap1.