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This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct ... See more...
Aliases for RASAL2 Gene
Aliases for RASAL2 Gene
External Ids for RASAL2 Gene
- HGNC: 9874
- Entrez Gene: 9462
- Ensembl: ENSG00000075391
- OMIM: 606136
- UniProtKB: Q9UJF2
Previous GeneCards Identifiers for RASAL2 Gene
- GC01P175834
- GC01P173491
- GC01P174643
- GC01P175303
- GC01P174795
- GC01P176329
- GC01P178063
- GC01P149291
Summaries for RASAL2 Gene
-
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for RASAL2 Gene
RASAL2 (RAS Protein Activator Like 2) is a Protein Coding gene. Diseases associated with RASAL2 include Breast Cancer. Among its related pathways are RET signaling and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is DAB2IP.
UniProtKB/Swiss-Prot Summary for RASAL2 Gene
-
Inhibitory regulator of the Ras-cyclic AMP pathway.
Additional gene information for RASAL2 Gene
- HGNC(9874)
- Entrez Gene(9462)
- Ensembl(ENSG00000075391)
- OMIM(606136)
- UniProtKB(Q9UJF2)
- Open Targets Platform(ENSG00000075391)
- Monarch Initiative
- Search for RASAL2 at DataMed
- Search for RASAL2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RASAL2 Gene
Genomics for RASAL2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RASAL2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RASAL2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RASAL2
- Top Transcription factor binding sites by QIAGEN in the RASAL2 gene promoter:
-
- E47
- HFH-1
- Hlf
- HNF-1A
- Nkx2-2
- NRSF form 1
- NRSF form 2
- p300
- Sox9
- Zic1
Genomic Locations for RASAL2 Gene
Genomic Locations for RASAL2 Gene
- chr1:178,093,729-178,484,147
- (GRCh38/hg38)
- Size:
- 390,419 bases
- Orientation:
- Plus strand
- chr1:178,062,864-178,448,649
- (GRCh37/hg19)
- Size:
- 385,786 bases
- Orientation:
- Plus strand
Genomic View for RASAL2 Gene
Genes around RASAL2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q25.2 by HGNC
- 1q25.2 by Entrez Gene
- 1q25.2 by Ensembl
RASAL2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RASAL2 Gene
Proteins for RASAL2 Gene
-
Protein details for RASAL2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UJF2-NGAP_HUMAN
- Recommended name:
- Ras GTPase-activating protein nGAP
- Protein Accession:
- Q9UJF2
- F8W755
- O95174
- Q2TB22
- Q5TFU9
Protein attributes for RASAL2 Gene
- Size:
- 1139 amino acids
- Molecular mass:
- 128558 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAI10612.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for RASAL2 Gene
Post-translational modifications for RASAL2 Gene
Other Protein References for RASAL2 Gene
Antibody Products
- G Biosciences Immunotag™ RASAL2 Antibody and Immunotag™ NGAP Polyclonal Antibody
-
Custom Antibody ServicesOriGene Antibodies for RASAL2
- Novus Biologicals Antibodies for RASAL2
- Invitrogen Antibodies for RASAL2 (AFLGC-RASAL2)
-
Biorbyt antibodies for RASAL2
-
Boster Bio Antibodies for RASAL2
-
Santa Cruz Biotechnology (SCBT) Antibodies for RASAL2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RASAL2
- Origene Custom Protein Services for RASAL2
- Novus Biologicals proteins for RASAL2
-
Signalway Proteins for RASAL2
No data available for DME Specific Peptides for RASAL2 Gene
Domains & Families for RASAL2 Gene
Gene Families for RASAL2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for RASAL2 Gene
- InterPro:
- Blocks:
-
- C2 domain
- Pleckstrin-like
- Ras GTPase-activating protein
- ProtoNet:
Suggested Antigen Peptide Sequences for RASAL2 Gene
- GenScript: Design optimal peptide antigens:
-
- RAS protein activator-like 2 (NGAP_HUMAN)
- RASAL2 protein (Q2TB22_HUMAN)
- RAS protein activator like 2 (Q5TFV0_HUMAN)
- RASAL2 protein (Q6P4F9_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RASAL2 Gene
Function for RASAL2 Gene
Molecular function for RASAL2 Gene
- UniProtKB/Swiss-Prot Function:
- Inhibitory regulator of the Ras-cyclic AMP pathway.
Phenotypes From GWAS Catalog for RASAL2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | TAS,IEA | -- |
| GO:0005515 | protein binding | IPI | 18985028 |
Phenotypes for RASAL2 Gene
- MGI mutant phenotypes for RASAL2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for RASAL2:
Animal Models for RASAL2 Gene
- MGI Knock Outs for RASAL2:
-
- Rasal2 Rasal2<tm1a(EUCOMM)Wtsi>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RASAL2 - Select products 50% OFF >
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-
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASAL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RASAL2
miRNA for RASAL2 Gene
- miRTarBase miRNAs that target RASAL2
-
- hsa-miR-98-5p (MIRT027468)
- hsa-miR-26b-5p (MIRT029026)
- hsa-miR-15a-3p (MIRT038984)
- hsa-miR-125b-5p (MIRT045969)
- hsa-miR-99a-5p (MIRT048603)
- hsa-miR-92a-3p (MIRT048987)
- hsa-miR-203a-3p (MIRT053439)
- hsa-miR-6867-5p (MIRT469542)
- hsa-miR-511-3p (MIRT469543)
- hsa-miR-5583-3p (MIRT469544)
- mmu-miR-377-3p (MIRT581421)
- mmu-miR-410-3p (MIRT581422)
- mmu-miR-344d-3p (MIRT581423)
- mmu-miR-344e-3p (MIRT581424)
- mmu-miR-466a-5p (MIRT581425)
- mmu-miR-466e-5p (MIRT581426)
- mmu-miR-1187 (MIRT581427)
- mmu-miR-466p-5p (MIRT581428)
- mmu-miR-669f-3p (MIRT589082)
- mmu-miR-669m-3p (MIRT589083)
- mmu-miR-466n-3p (MIRT589084)
- mmu-miR-467g (MIRT589085)
- mmu-miR-466d-3p (MIRT589086)
- mmu-miR-466e-3p (MIRT589087)
- mmu-miR-297b-3p (MIRT589088)
- mmu-miR-466a-3p (MIRT589089)
- mmu-miR-22-3p (MIRT589090)
- mmu-miR-105 (MIRT589091)
- mmu-miR-466f-5p (MIRT589092)
- mmu-miR-466f (MIRT589093)
- mmu-miR-466l-5p (MIRT589094)
- mmu-miR-466i-5p (MIRT589095)
- mmu-miR-466k (MIRT589096)
- mmu-miR-466d-5p (MIRT589097)
- mmu-miR-669m-5p (MIRT589098)
- mmu-miR-466n-5p (MIRT589099)
- mmu-miR-466j (MIRT589100)
- mmu-miR-466h-5p (MIRT589101)
- mmu-miR-466m-5p (MIRT589102)
- mmu-miR-708-5p (MIRT592970)
- mmu-miR-28a-5p (MIRT592971)
- mmu-miR-327 (MIRT600477)
- mmu-miR-3089-5p (MIRT600478)
- mmu-miR-1195 (MIRT600479)
- mmu-miR-490-3p (MIRT600480)
- mmu-miR-5135 (MIRT600481)
- mmu-miR-139-5p (MIRT600482)
- mmu-miR-1912-3p (MIRT600483)
- hsa-miR-129-5p (MIRT654442)
- hsa-miR-4639-5p (MIRT654443)
- hsa-miR-513c-3p (MIRT654444)
- hsa-miR-513a-3p (MIRT654445)
- hsa-miR-3606-3p (MIRT654446)
- hsa-miR-30b-5p (MIRT732514)
- hsa-miR-30c-5p (MIRT732515)
- hsa-miR-136-5p (MIRT734470)
- mmu-miR-466f-3p (MIRT791430)
- mmu-miR-466q (MIRT791572)
- mmu-miR-467f (MIRT791711)
- mmu-miR-669c-3p (MIRT791880)
miRNA Products
Inhibitory RNA Products
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Clone Products
- Applied Biological Materials (abm): Clones for RASAL2 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for RASAL2
- Addgene plasmids for RASAL2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASAL2
Cell Line Products
-
Horizon Cell Lines for RASAL2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RASAL2 Gene
Localization for RASAL2 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| plasma membrane | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| golgi apparatus | 1 |
- Focal adhesion sites (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for RASAL2 Gene
Pathways & Interactions for RASAL2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
.92
|
| 2 | Developmental Biology |
.51
|
|
| 3 | Cytokine Signaling in Immune system | ||
| 4 | HIV Life Cycle |
.45
|
|
| 5 | Innate Immune System |
.61
|
|
Pathways by source for RASAL2 Gene
53 Reactome pathways for RASAL2 Gene
1 KEGG pathway for RASAL2 Gene
1 Cell Signaling Technology pathway for RASAL2 Gene
Interacting Proteins for RASAL2 Gene
Selected Interacting proteins:
Q9UJF2-NGAP_HUMAN
ENSP00000356621
for RASAL2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for RASAL2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0007165 | signal transduction | IEA,TAS | 9877179 |
| GO:0043087 | regulation of GTPase activity | IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
No data available for SIGNOR curated interactions for RASAL2 Gene
Transcripts for RASAL2 Gene
mRNA/cDNA for RASAL2 Gene
- 2 REFSEQ mRNAs :
- 19 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000367649 4378 nts (view in UCSC)
- ENST00000433130 2385 nts (view in UCSC)
- ENST00000462775 14453 nts (view in UCSC)
- ENST00000463079 650 nts (view in UCSC)
- ENST00000465723 718 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RASAL2 - Select products 50% OFF >
- * RASAL2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for RASAL2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASAL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RASAL2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASAL2
- Browse OriGene Inhibitory RNA Products For RASAL2
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Clone Products
- Applied Biological Materials (abm): Clones for RASAL2 - Select products 50% OFF >
- * RASAL2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RASAL2
- Addgene plasmids for RASAL2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASAL2
Relevant External Links for RASAL2 Gene
- GeneLoc Exon Structure for
- RASAL2
Expression for RASAL2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Eye (Sensory Organs)
This gene is overexpressed in Synovial fluid (13.9), Milk (11.6), and Uterus (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RASAL2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RASAL2
SOURCE GeneReport for Unigene cluster for RASAL2 Gene:
Hs.496139Evidence on tissue expression from TISSUES for RASAL2 Gene
- Heart(4.3)
- Liver(4.3)
- Nervous system(4)
- Blood(2.2)
Primer Products
-
OriGene qPCR primer pairs for RASAL2
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RASAL2 Gene
Orthologs for RASAL2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RASAL2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RASAL2 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RASAL2 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rasal2 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RASAL2 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RASAL2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RASAL2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RASAL2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rasal2 30 |
|
||
| Str.11362 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.1575 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rasal2 30 31 |
|
OneToOne | |
| Dr.24417 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7799 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG42684 31 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | gap-2 31 32 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | BUD2 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.6146 31 |
|
OneToMany |
- Species where no ortholog for RASAL2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for RASAL2 Gene
- ENSEMBL:
- Gene Tree for RASAL2 (if available)
- TreeFam:
- Gene Tree for RASAL2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RASAL2: view image
Paralogs for RASAL2 Gene
Paralogs for RASAL2 Gene
(4) SIMAP similar genes for RASAL2 Gene using alignment to 4 proteins:
- NGAP_HUMAN
- B1AKC7_HUMAN
- H0Y638_HUMAN
- Q6P4F9_HUMAN
Variants for RASAL2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RASAL2 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 709358 | Likely Benign: not provided | 178,443,046(+) | G/A | SYNONYMOUS_VARIANT | |
| 719624 | Benign: not provided | 178,441,554(+) | C/T | SYNONYMOUS_VARIANT | |
| 721721 | Likely Benign: not provided | 178,094,575(+) | C/A | MISSENSE_VARIANT | |
| 723880 | Likely Benign: not provided | 178,442,854(+) | T/C | SYNONYMOUS_VARIANT | |
| 723881 | Likely Benign: not provided | 178,457,833(+) | C/T | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2534493 | CNV | deletion | 19546169 |
| esv2606666 | CNV | deletion | 19546169 |
| esv3416886 | CNV | duplication | 20981092 |
| esv3588029 | CNV | loss | 21293372 |
| esv3588030 | CNV | loss | 21293372 |
| esv3588031 | CNV | loss | 21293372 |
| esv3588032 | CNV | loss | 21293372 |
| esv3588033 | CNV | loss | 21293372 |
| nsv1142076 | CNV | tandem duplication | 24896259 |
| nsv473443 | CNV | novel sequence insertion | 20440878 |
| nsv508670 | CNV | deletion | 20534489 |
| nsv548252 | CNV | gain | 21841781 |
| nsv946518 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
5.63% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.40;
42.45% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RASAL2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RASAL2 Gene
Disorders for RASAL2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| breast cancer |
|
|
Search RASAL2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RASAL2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RASAL2 Gene
Publications for RASAL2 Gene
- A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25. (PMID: 9877179) Noto S … Hatakeyama M (FEBS letters 1998) 2 3 4
- Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. (PMID: 20571754) Fontaine-Bisson B … Franks PW (Diabetologia 2010) 3 41
- Analyses of shared genetic factors between asthma and obesity in children. (PMID: 20816195) Melén E … Lasky-Su J (The Journal of allergy and clinical immunology 2010) 3 41
- Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (PMID: 19079260) Thorleifsson G … Stefansson K (Nature genetics 2009) 3 41
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
ExternalLinks
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- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for RASAL2
- Signalway Proteins for RASAL2
Sources for RASAL2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB