Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct ... See more...
Aliases for RASAL2 Gene
Aliases for RASAL2 Gene
External Ids for RASAL2 Gene
- HGNC: 9874
- NCBI Entrez Gene: 9462
- Ensembl: ENSG00000075391
- OMIM®: 606136
- UniProtKB/Swiss-Prot: Q9UJF2
Previous GeneCards Identifiers for RASAL2 Gene
- GC01P175834
- GC01P173491
- GC01P174643
- GC01P175303
- GC01P174795
- GC01P176329
- GC01P178063
- GC01P149291
Summaries for RASAL2 Gene
-
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for RASAL2 Gene
RASAL2 (RAS Protein Activator Like 2) is a Protein Coding gene. Among its related pathways are RET signaling and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include GTPase activator activity. An important paralog of this gene is DAB2IP.
UniProtKB/Swiss-Prot Summary for RASAL2 Gene
-
Inhibitory regulator of the Ras-cyclic AMP pathway.
Additional gene information for RASAL2 Gene
- HGNC (9874)
- NCBI Entrez Gene (9462)
- Ensembl (ENSG00000075391)
- OMIM® (606136)
- UniProtKB/Swiss-Prot (Q9UJF2)
- Open Targets Platform(ENSG00000075391)
- Monarch Initiative
- Alliance of Genome Resources
- Search for RASAL2 at DataMed
- Search for RASAL2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RASAL2 Gene
Genomics for RASAL2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RASAL2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RASAL2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RASAL2
- Top Transcription factor binding sites by QIAGEN in the RASAL2 gene promoter:
-
- E47
- HFH-1
- Hlf
- HNF-1A
- Nkx2-2
- NRSF form 1
- NRSF form 2
- p300
- Sox9
- Zic1
Genomic Locations for RASAL2 Gene
Latest Assembly
- chr1:178,093,729-178,484,147
- (GRCh38/hg38)
- Size:
- 390,419 bases
- Orientation:
- Plus strand
Previous Assembly
- chr1:178,063,239-178,447,985
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 384,747 bases
- Orientation:
- Plus strand
Genomic View for RASAL2 Gene
Genes around RASAL2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q25.2 by HGNC
- 1q25.2 by Entrez Gene
- 1q25.2 by Ensembl
RASAL2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RASAL2 Gene
Proteins for RASAL2 Gene
-
Protein details for RASAL2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UJF2-NGAP_HUMAN
- Recommended name:
- Ras GTPase-activating protein nGAP
- Protein Accession:
- Q9UJF2
- F8W755
- O95174
- Q2TB22
- Q5TFU9
Protein attributes for RASAL2 Gene
- Size:
- 1139 amino acids
- Molecular mass:
- 128558 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAI10612.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
Protein Expression for RASAL2 Gene
Post-translational modifications for RASAL2 Gene
Other Protein References for RASAL2 Gene
Antibodies for research
- G Biosciences Immunotag™ RASAL2 Antibody and Immunotag™ NGAP Polyclonal Antibody
-
Custom Antibody ServicesOriGene Antibodies for RASAL2
- Novus Biologicals Antibodies for RASAL2
- Invitrogen Antibodies for RASAL2 (AFLGC-RASAL2)
-
Biorbyt antibodies for RASAL2
-
Boster Bio Antibodies for RASAL2
-
Custom Antibody ServicesProSci Antibodies for RASAL2
-
Santa Cruz Biotechnology (SCBT) Antibodies for RASAL2
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RASAL2
- Origene Custom Protein Services for RASAL2
- Novus Biologicals proteins for RASAL2
Assay products for research
No data available for DME Specific Peptides for RASAL2 Gene
Domains & Families for RASAL2 Gene
Gene Families for RASAL2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for RASAL2 Gene
- InterPro:
- Blocks:
-
- C2 domain
- Pleckstrin-like
- Ras GTPase-activating protein
Suggested Antigen Peptide Sequences for RASAL2 Gene
- GenScript: Design optimal peptide antigens:
-
- RAS protein activator-like 2 (NGAP_HUMAN)
- RASAL2 protein (Q2TB22_HUMAN)
- RAS protein activator like 2 (Q5TFV0_HUMAN)
- RASAL2 protein (Q6P4F9_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RASAL2 Gene
Function for RASAL2 Gene
Molecular function for RASAL2 Gene
- UniProtKB/Swiss-Prot Function:
- Inhibitory regulator of the Ras-cyclic AMP pathway.
Phenotypes From GWAS Catalog for RASAL2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 18985028 |
Phenotypes for RASAL2 Gene
- MGI mutant phenotypes for RASAL2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for RASAL2:
Animal Models for RASAL2 Gene
- MGI Knock Outs for RASAL2:
-
- Rasal2 Rasal2<tm1a(EUCOMM)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for RASAL2 - Starting at $85 >
- * RASAL2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for RASAL2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASAL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RASAL2
miRNA for RASAL2 Gene
- miRTarBase miRNAs that target RASAL2
-
- hsa-miR-98-5p (MIRT027468)
- hsa-miR-26b-5p (MIRT029026)
- hsa-miR-15a-3p (MIRT038984)
- hsa-miR-125b-5p (MIRT045969)
- hsa-miR-99a-5p (MIRT048603)
- hsa-miR-92a-3p (MIRT048987)
- hsa-miR-203a-3p (MIRT053439)
- hsa-miR-6867-5p (MIRT469542)
- hsa-miR-511-3p (MIRT469543)
- hsa-miR-5583-3p (MIRT469544)
- mmu-miR-377-3p (MIRT581421)
- mmu-miR-410-3p (MIRT581422)
- mmu-miR-344d-3p (MIRT581423)
- mmu-miR-344e-3p (MIRT581424)
- mmu-miR-466a-5p (MIRT581425)
- mmu-miR-466e-5p (MIRT581426)
- mmu-miR-1187 (MIRT581427)
- mmu-miR-466p-5p (MIRT581428)
- mmu-miR-669f-3p (MIRT589082)
- mmu-miR-669m-3p (MIRT589083)
- mmu-miR-466n-3p (MIRT589084)
- mmu-miR-467g (MIRT589085)
- mmu-miR-466d-3p (MIRT589086)
- mmu-miR-466e-3p (MIRT589087)
- mmu-miR-297b-3p (MIRT589088)
- mmu-miR-466a-3p (MIRT589089)
- mmu-miR-22-3p (MIRT589090)
- mmu-miR-105 (MIRT589091)
- mmu-miR-466f-5p (MIRT589092)
- mmu-miR-466f (MIRT589093)
- mmu-miR-466l-5p (MIRT589094)
- mmu-miR-466i-5p (MIRT589095)
- mmu-miR-466k (MIRT589096)
- mmu-miR-466d-5p (MIRT589097)
- mmu-miR-669m-5p (MIRT589098)
- mmu-miR-466n-5p (MIRT589099)
- mmu-miR-466j (MIRT589100)
- mmu-miR-466h-5p (MIRT589101)
- mmu-miR-466m-5p (MIRT589102)
- mmu-miR-708-5p (MIRT592970)
- mmu-miR-28a-5p (MIRT592971)
- mmu-miR-327 (MIRT600477)
- mmu-miR-3089-5p (MIRT600478)
- mmu-miR-1195 (MIRT600479)
- mmu-miR-490-3p (MIRT600480)
- mmu-miR-5135 (MIRT600481)
- mmu-miR-139-5p (MIRT600482)
- mmu-miR-1912-3p (MIRT600483)
- hsa-miR-129-5p (MIRT654442)
- hsa-miR-4639-5p (MIRT654443)
- hsa-miR-513c-3p (MIRT654444)
- hsa-miR-513a-3p (MIRT654445)
- hsa-miR-3606-3p (MIRT654446)
- hsa-miR-30b-5p (MIRT732514)
- hsa-miR-30c-5p (MIRT732515)
- hsa-miR-136-5p (MIRT734470)
- mmu-miR-466f-3p (MIRT791430)
- mmu-miR-466q (MIRT791572)
- mmu-miR-467f (MIRT791711)
- mmu-miR-669c-3p (MIRT791880)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASAL2
- Browse OriGene Inhibitory RNA Products For RASAL2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RASAL2
Clone products for research
- Applied Biological Materials (abm): Clones for RASAL2 - Starting at $45 >
- * RASAL2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for RASAL2
- Addgene plasmids for RASAL2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASAL2
Cell Lines for research
-
Horizon Cell Lines for RASAL2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for RASAL2 Gene
Localization for RASAL2 Gene
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| plasma membrane | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
- Focal adhesion sites (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for RASAL2 Gene
Pathways & Interactions for RASAL2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
.92
|
| 2 | Developmental Biology |
.51
|
|
| 3 | Cytokine Signaling in Immune system | ||
| 4 | HIV Life Cycle |
.45
|
|
| 5 | Innate Immune System |
.61
|
|
Pathways by source for RASAL2 Gene
53 Reactome pathways for RASAL2 Gene
1 KEGG pathway for RASAL2 Gene
1 Cell Signaling Technology pathway for RASAL2 Gene
Interacting Proteins for RASAL2 Gene
Selected Interacting proteins:
Q9UJF2-NGAP_HUMAN
ENSP00000356621
for RASAL2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for RASAL2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0007165 | signal transduction | IEA,TAS | 9877179 |
| GO:0043087 | regulation of GTPase activity | IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
No data available for SIGNOR curated interactions for RASAL2 Gene
Transcripts for RASAL2 Gene
mRNA/cDNA for RASAL2 Gene
- 2 REFSEQ mRNAs :
- 19 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000367649 9843 nts (view in UCSC)
- ENST00000433130 2385 nts (view in UCSC)
- ENST00000462775 14453 nts (view in UCSC)
- ENST00000463079 650 nts (view in UCSC)
- ENST00000465723 718 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for RASAL2 - Starting at $85 >
- * RASAL2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for RASAL2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASAL2
-
Santa Cruz Biotechnology (SCBT) CRISPR for RASAL2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASAL2
- Browse OriGene Inhibitory RNA Products For RASAL2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RASAL2
Clone products for research
- Applied Biological Materials (abm): Clones for RASAL2 - Starting at $45 >
- * RASAL2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for RASAL2
- Addgene plasmids for RASAL2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASAL2
Relevant External Links for RASAL2 Gene
- GeneLoc Exon Structure for
- RASAL2
Expression for RASAL2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Eye (Sensory Organs)
This gene is overexpressed in Synovial fluid (13.9), Milk (11.6), and Uterus (6.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RASAL2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RASAL2
SOURCE GeneReport for Unigene cluster for RASAL2 Gene:
Hs.496139Evidence on tissue expression from TISSUES for RASAL2 Gene
- Heart(4.3)
- Liver(4.3)
- Nervous system(3.9)
- Blood(2.1)
Primer products for research
-
OriGene qPCR primer pairs for RASAL2
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RASAL2 Gene
Orthologs for RASAL2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RASAL2 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RASAL2 29 30 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RASAL2 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rasal2 29 16 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RASAL2 29 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RASAL2 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RASAL2 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RASAL2 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rasal2 29 |
|
||
| Str.11362 29 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.1575 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rasal2 29 30 |
|
OneToOne | |
| Dr.24417 29 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.7799 29 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG42684 30 |
|
OneToMany | |
| Worm (Caenorhabditis elegans) |
Secernentea | gap-2 30 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | BUD2 30 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.6146 30 |
|
OneToMany |
- Species where no ortholog for RASAL2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for RASAL2 Gene
- ENSEMBL:
- Gene Tree for RASAL2 (if available)
- TreeFam:
- Gene Tree for RASAL2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RASAL2: view image
- Alliance of Genome Resources:
- Additional Orthologs for RASAL2
Paralogs for RASAL2 Gene
Paralogs for RASAL2 Gene
(4) SIMAP similar genes for RASAL2 Gene using alignment to 4 proteins:
- NGAP_HUMAN
- B1AKC7_HUMAN
- H0Y638_HUMAN
- Q6P4F9_HUMAN
Variants for RASAL2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RASAL2 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs142556497 | Benign: not provided | 178,441,554(+) |
C/T NM_170692.3(RASAL2):c.834C>T (p.Thr278=) |
SYNONYMOUS | |
| rs144412569 | Benign: not provided | 178,458,424(+) |
G/C NM_170692.3(RASAL2):c.3132G>C (p.Val1044=) |
SYNONYMOUS | |
| rs144763240 | Likely Benign: not provided | 178,442,854(+) |
T/C NM_170692.3(RASAL2):c.1107T>C (p.Leu369=) |
SYNONYMOUS | |
| rs146496466 | Likely Benign: not provided | 178,457,833(+) |
C/T NM_170692.3(RASAL2):c.2541C>T (p.Ser847=) |
SYNONYMOUS | |
| rs193921085 | Uncertain Significance: Malignant tumor of prostate | 178,473,216(+) |
G/T NM_004841.4(RASAL2):c.3397G>T (p.Glu1133Ter) |
NONSENSE |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2534493 | CNV | deletion | 19546169 |
| esv2606666 | CNV | deletion | 19546169 |
| esv3416886 | CNV | duplication | 20981092 |
| esv3588029 | CNV | loss | 21293372 |
| esv3588030 | CNV | loss | 21293372 |
| esv3588031 | CNV | loss | 21293372 |
| esv3588032 | CNV | loss | 21293372 |
| esv3588033 | CNV | loss | 21293372 |
| nsv1142076 | CNV | tandem duplication | 24896259 |
| nsv473443 | CNV | novel sequence insertion | 20440878 |
| nsv508670 | CNV | deletion | 20534489 |
| nsv548252 | CNV | gain | 21841781 |
| nsv946518 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
5.63% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.40;
42.45% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RASAL2 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RASAL2 Gene
Disorders for RASAL2 Gene
Additional Disease Information for RASAL2
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for RASAL2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for RASAL2 Gene
Publications for RASAL2 Gene
- A novel human RasGAP-like gene that maps within the prostate cancer susceptibility locus at chromosome 1q25. (PMID: 9877179) Noto S … Hatakeyama M (FEBS letters 1998) 2 3 4
- Evaluating the discriminative power of multi-trait genetic risk scores for type 2 diabetes in a northern Swedish population. (PMID: 20571754) Fontaine-Bisson B … Franks PW (Diabetologia 2010) 3 40
- Analyses of shared genetic factors between asthma and obesity in children. (PMID: 20816195) Melén E … Lasky-Su J (The Journal of allergy and clinical immunology 2010) 3 40
- Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (PMID: 19079260) Thorleifsson G … Stefansson K (Nature genetics 2009) 3 40
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4
ExternalLinks
Products for RASAL2 Gene
- Custom Antibody ServicesOriGene Antibodies for RASAL2
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RASAL2
- Origene Custom Protein Services for RASAL2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RASAL2
- Browse OriGene Inhibitory RNA Products For RASAL2
- OriGene qPCR primer pairs for RASAL2
- OriGene CRISPR knockouts for RASAL2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For RASAL2
- Sino Biological Human cDNA Clone for RASAL2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RASAL2
- Novus Biologicals proteins for RASAL2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for RASAL2 (AFLGC-RASAL2)
- VectorBuilder Custom and pre-made DNA vectors for RASAL2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RASAL2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RASAL2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RASAL2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RASAL2
- Addgene plasmids for RASAL2
- antibodies-online: Show 13 available RASAL2 Antibodies ranked by validation data
- Compare Top RASAL2 Antibodies
- antibodies-online: Search results for available RASAL2 related products ranked by validation data
- antibodies-online: Search results for available RASAL2 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for RASAL2
- Search Santa Cruz Biotechnology (SCBT) for RASAL2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RASAL2
- Horizon Cell Lines for RASAL2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RASAL2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RASAL2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RASAL2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RASAL2
- Boster Bio Antibodies for RASAL2
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for RASAL2
Sources for RASAL2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources