RARG Gene (Protein Coding)

Retinoic Acid Receptor Gamma

GC12M053210
GIFtS:
47
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RAR... See more...

Aliases for RARG Gene

Aliases for RARG Gene

  • Retinoic Acid Receptor Gamma 2 3 4 5
  • NR1B3 2 3 4
  • Nuclear Receptor Subfamily 1 Group B Member 3 3 4
  • RAR-Gamma 3 4
  • RARC 2 3
  • Retinoic Acid Nuclear Receptor Gamma Variant 1 3
  • Retinoic Acid Nuclear Receptor Gamma Variant 2 3
  • Retinoic Acid Receptor, Gamma 2
  • RARG 5

External Ids for RARG Gene

Previous GeneCards Identifiers for RARG Gene

  • GC12M053763
  • GC12M053518
  • GC12M053321
  • GC12M051890
  • GC12M053604
  • GC12M050646

Summaries for RARG Gene

Entrez Gene Summary for RARG Gene

  • This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

GeneCards Summary for RARG Gene

RARG (Retinoic Acid Receptor Gamma) is a Protein Coding gene. Diseases associated with RARG include Embryonal Carcinoma and Exfoliative Ichthyosis. Among its related pathways are Signaling by GPCR and all-trans-Retinoic Acid Mediated Apoptosis. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is RARB.

UniProtKB/Swiss-Prot Summary for RARG Gene

  • Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).

Tocris Summary for RARG Gene

  • Retinoic acid receptors (RARs) are nuclear hormone receptors of the NR1B class, which function as heterodimers with retinoid X receptors (RXRs). There are three distinct RAR subtypes: RARalpha, present in most tissue types; and RARbeta and RARgamma, with more selective expression.

Gene Wiki entry for RARG Gene

Additional gene information for RARG Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RARG Gene

Genomics for RARG Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for RARG Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around RARG on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RARG

Top Transcription factor binding sites by QIAGEN in the RARG gene promoter:
  • p300
  • PPAR-gamma1
  • PPAR-gamma2

Genomic Locations for RARG Gene

Genomic Locations for RARG Gene
chr12:53,210,566-53,232,980
(GRCh38/hg38)
Size:
22,415 bases
Orientation:
Minus strand
chr12:53,604,353-53,626,764
(GRCh37/hg19)
Size:
22,412 bases
Orientation:
Minus strand

Genomic View for RARG Gene

Genes around RARG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
RARG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for RARG Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for RARG Gene

Proteins for RARG Gene

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  • Protein details for RARG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P13631-RARG_HUMAN
    Recommended name:
    Retinoic acid receptor gamma
    Protein Accession:
    P13631
    Secondary Accessions:
    • B7Z492
    • B7Z4F1
    • B7ZAE4
    • J3KNP6
    • P22932
    • Q15281
    • Q52LZ8
    • Q9BYX8
    • Q9H1I3
    • Q9UJ38

    Protein attributes for RARG Gene

    Size:
    454 amino acids
    Molecular mass:
    50342 Da
    Quaternary structure:
    • Homodimer. Heterodimer with a RXR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Forms a complex with PUS1 and the SRA1 RNA in the nucleus.
    SequenceCaution:
    • Sequence=CAA40548.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for RARG Gene

    Alternative splice isoforms for RARG Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for RARG Gene

Protein Expression for RARG Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for RARG Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for RARG Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for RARG Gene

Domains & Families for RARG Gene

Gene Families for RARG Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Cancer-related genes
  • FDA approved drug targets
  • Nuclear receptors
  • Plasma proteins
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for RARG Gene

InterPro:
Blocks:
  • Steroid hormone receptor signature
  • Retinoic acid receptor (1B nuclear receptor) signature
ProtoNet:

Suggested Antigen Peptide Sequences for RARG Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ75202, highly similar to Homo sapiens, retinoic acid receptor, gamma (A8K3H3_HUMAN)
  • cDNA FLJ54482, highly similar to Retinoic acid receptor gamma-2 (B7Z4F1_HUMAN)
  • Retinoic acid nuclear receptor gamma variant 2 (F1D8P1_HUMAN)
  • Retinoic acid receptor gamma (Q9BZI0_HUMAN)
  • Nuclear receptor subfamily 1 group B member 3 (RARG_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P13631

UniProtKB/Swiss-Prot:

RARG_HUMAN :
  • Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • Belongs to the nuclear hormone receptor family. NR1 subfamily.
Domain:
  • Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
Family:
  • Belongs to the nuclear hormone receptor family. NR1 subfamily.
genes like me logo Genes that share domains with RARG: view

Function for RARG Gene

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Molecular function for RARG Gene

UniProtKB/Swiss-Prot Function:
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
GENATLAS Biochemistry:
retinoic acid receptor binding and activated by both all-trans (T-RA) and its 9-cis isomer (9-cis-RA) retinoic acids,gamma subunit,steroid/thyroid hormone receptor superfamily

Phenotypes From GWAS Catalog for RARG Gene

Gene Ontology (GO) - Molecular Function for RARG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000976 transcription regulatory region sequence-specific DNA binding IBA --
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISM 19274049
GO:0003677 DNA binding ISS --
GO:0003700 DNA-binding transcription factor activity ISS --
genes like me logo Genes that share ontologies with RARG: view
genes like me logo Genes that share phenotypes with RARG: view

Animal Models for RARG Gene

MGI Knock Outs for RARG:

Animal Model Products

  • Taconic Biosciences Mouse Models for RARG

CRISPR Products

Targeted motifs for RARG Gene
HOMER Transcription Factor Regulatory Elements motif RARG
  • Consensus sequence: AGGTCAAGGTCA Submotif: canonical Cell Type: ES GEO ID: GSE30538

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RARG

Clone Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology and Transcription Factor Targets for RARG Gene

Localization for RARG Gene

Subcellular locations from UniProtKB/Swiss-Prot for RARG Gene

Nucleus. Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for RARG gene
Compartment Confidence
nucleus 5
extracellular 2
plasma membrane 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
cytosol 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for RARG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000790 nuclear chromatin IDA,ISA --
GO:0005634 nucleus IBA,ISS --
GO:0005654 nucleoplasm TAS --
GO:0005667 transcription factor complex ISS --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with RARG: view

Pathways & Interactions for RARG Gene

genes like me logo Genes that share pathways with RARG: view

Pathways by source for RARG Gene

5 Qiagen pathways for RARG Gene
  • all-trans-Retinoic Acid Mediated Apoptosis
  • all-trans-Retinoic Acid Signaling in Brain
  • Molecular Mechanisms of Cancer
  • Nuclear Receptor Activation by Vitamin-A
  • RAR-Gamma-RXR-Alpha Degradation
1 GeneTex pathway for RARG Gene

SIGNOR curated interactions for RARG Gene

Activates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for RARG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II ISS --
GO:0001843 neural tube closure IEA --
GO:0002063 chondrocyte development IEA --
GO:0002068 glandular epithelial cell development IEA --
GO:0003417 growth plate cartilage development IEA --
genes like me logo Genes that share ontologies with RARG: view

Drugs & Compounds for RARG Gene

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(50) Drugs for RARG Gene - From: DrugBank, PharmGKB, ApexBio, DGIdb, IUPHAR, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Adapalene Approved Pharma Target, agonist, binder RAR尾 and RAR纬 agonist 90
Tazarotene Approved, Investigational Pharma Target, agonist, binder Topical retinoid;antiproliferative;inducer of TIG3 tumor suppressor 48
Tretinoin Approved, Investigational Nutra Agonist, Full agonist, Antagonist, Target, agonist, binder 273
Acitretin Approved Pharma Target, agonist Metabolite of etretinate 33
Alitretinoin Approved, Investigational Pharma Agonist, Target, agonist 17

(5) Additional Compounds for RARG Gene - From: Novoseek and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
retinoic acid
302-79-4
EC 23
104561-41-3
Liarozole dihydrochloride

(5) Tocris Compounds for RARG Gene

Compound Action Cas Number
EC 23 Synthetic retinoid; induces differentiation of stem cells 104561-41-3
Isotretinoin Endogenous agonist for retinoic acid receptors; inducer of neuronal differentiation 4759-48-2
Liarozole dihydrochloride Blocks retinoic acid metabolism
Retinoic acid Endogenous retinoic acid receptor agonist 302-79-4
TTNPB Retinoic acid analog; RAR agonist 71441-28-6

(21) ApexBio Compounds for RARG Gene

Compound Action Cas Number
Acitretin Metabolite of etretinate 55079-83-9
Acitretin sodium 925701-88-8
Adapalene RAR尾 and RAR纬 agonist 106685-40-9
Adarotene Apoptosis inducer/DNA damage agent 496868-77-0
AGN 194310 pan-RAR antagonist 229961-45-9
BMS 453 RAR agonist 166977-43-1
BMS 493 Pan-RAR inverse agonist 215030-90-3
BMS 961 Selective RARγ agonist 185629-22-5
CD 1530 RARγ receptor agonist,potent and selective 107430-66-0
CD 2665 Selective RARβ/γ antagonist 170355-78-9
CD 437 RARγ-selective agonist,potent and cell-permeable 125316-60-1
Ch 55 110368-33-7
ER 50891 187400-85-7
LE 135 155877-83-1
MM 11253 345952-44-5
Palovarotene 410528-02-8
Talarozole Cytochrome P450 inhibitor 201410-53-9
Tazarotene Topical retinoid;antiproliferative;inducer of TIG3 tumor suppressor 118292-40-3
Tretinoin (Aberela) 302-79-4
TTNPB (Arotinoid Acid) Potent RAR agonist 71441-28-6
Vitamin A Acetate Unsaturated nutritional hydrocarbons 127-47-9
genes like me logo Genes that share compounds with RARG: view

Drug Products

Transcripts for RARG Gene

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  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
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mRNA/cDNA for RARG Gene

5 REFSEQ mRNAs :
27 NCBI additional mRNA sequence :
18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RARG

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for RARG Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b · 5c · 5d · 5e ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b · 10c ^
SP1: - - - - - - -
SP2: - - - - - - -
SP3: - - - - - - - - - - - -
SP4: -
SP5: - - - - - - - - - - - - - -
SP6: - - -
SP7: - -
SP8: - - -
SP9: - - - - - - - -
SP10: - - - - -
SP11: - - - - - -
SP12:
SP13:
SP14:

ExUns: 11 ^ 12 ^ 13a · 13b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:

Relevant External Links for RARG Gene

GeneLoc Exon Structure for
RARG

Expression for RARG Gene

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  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for RARG Gene

mRNA expression in normal human tissues for RARG Gene
mRNA expression by GTEx for RARG GenemRNA expression by BioGPS for RARG Gene

mRNA differential expression in normal tissues according to GTEx for RARG Gene

This gene is overexpressed in Esophagus - Mucosa (x6.4), Skin - Sun Exposed (Lower leg) (x5.0), and Skin - Not Sun Exposed (Suprapubic) (x4.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RARG Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RARG

SOURCE GeneReport for Unigene cluster for RARG Gene:

Hs.1497

mRNA Expression by UniProt/SwissProt for RARG Gene:

P13631-RARG_HUMAN
Tissue specificity: Expressed in aortic endothelial cells (at protein level).

Evidence on tissue expression from TISSUES for RARG Gene

  • Nervous system(4.5)
  • Intestine(4.4)
  • Blood(4.4)
  • Skin(3)
  • Muscle(2.3)
  • Lung(2.2)
  • Kidney(2.2)
  • Heart(2.1)
  • Thyroid gland(2.1)
genes like me logo Genes that share expression patterns with RARG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for RARG Gene

Orthologs for RARG Gene

This gene was present in the common ancestor of animals.

Orthologs for RARG Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
 Mammalia RARG 30 31
  • 99.56 (n)
 OneToOne
Dog
(Canis familiaris)
 Mammalia RARG 30 31
  • 93.52 (n)
 OneToOne
Cow
(Bos Taurus)
 Mammalia RARG 30 31
  • 93.29 (n)
 OneToOne
Mouse
(Mus musculus)
 Mammalia Rarg 30 17 31
  • 89.9 (n)
 OneToOne
Rat
(Rattus norvegicus)
 Mammalia Rarg 30
  • 89.16 (n)
Platypus
(Ornithorhynchus anatinus)
 Mammalia RARG 31
  • 80 (a)
 OneToOne
Lizard
(Anolis carolinensis)
 Reptilia RARG 31
  • 79 (a)
 OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
 Amphibia LOC100485387 30
  • 73.19 (n)
Zebrafish
(Danio rerio)
 Actinopterygii rargb 30 31
  • 79.16 (n)
 OneToMany
rarga 31
  • 73 (a)
 OneToMany
Fruit Fly
(Drosophila melanogaster)
 Insecta Eip75B 32
  • 32 (a)
Worm
(Caenorhabditis elegans)
 Secernentea sex-1 32
  • 30 (a)
Sea Squirt
(Ciona savignyi)
 Ascidiacea CSA.8261 31
  • 38 (a)
 OneToMany
Species where no ortholog for RARG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for RARG Gene

ENSEMBL:
Gene Tree for RARG (if available)
TreeFam:
Gene Tree for RARG (if available)
Aminode:
Evolutionary constrained regions (ECRs) for RARG: view image

Paralogs for RARG Gene

Paralogs for RARG Gene

(45) SIMAP similar genes for RARG Gene using alignment to 5 proteins:

  • RARG_HUMAN
  • H3BMH6_HUMAN
  • H3BMK1_HUMAN
  • H3BMY6_HUMAN
  • Q9BZI0_HUMAN
genes like me logo Genes that share paralogs with RARG: view

Variants for RARG Gene

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Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RARG Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
rs769476878 Likely Benign: Irido-corneo-trabecular dysgenesis 53,215,734(-) G/A MISSENSE_VARIANT,INTRON_VARIANT
VAR_036061 A breast cancer sample p.Gly430Ser
rs2229774 - p.Ser427Leu

Additional dbSNP identifiers (rs#s) for RARG Gene

Structural Variations from Database of Genomic Variants (DGV) for RARG Gene

Variant ID Type Subtype PubMed ID
dgv2644n54 CNV loss 21841781
dgv2645n54 CNV loss 21841781
nsv1070110 CNV deletion 25765185
nsv469404 CNV loss 19166990
nsv470295 CNV gain 18288195
nsv517066 CNV loss 19592680
nsv558994 CNV loss 21841781
nsv558996 CNV loss 21841781
nsv832417 CNV gain 17160897

Variation tolerance for RARG Gene

Residual Variation Intolerance Score: 25.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.20; 69.77% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for RARG Gene

Human Gene Mutation Database (HGMD)
RARG
SNPedia medical, phenotypic, and genealogical associations of SNPs for
RARG

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RARG Gene

Disorders for RARG Gene

MalaCards: The human disease database

(5) MalaCards diseases for RARG Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
embryonal carcinoma
  • primary extragonadal embryonal carcinoma
exfoliative ichthyosis
  • autosomal recessive exfoliative ichthyosis
diffuse palmoplantar keratoderma
  • diffuse ppk
nephrotic syndrome, type 3
  • nphs3
acute promyelocytic leukemia
  • apl
- elite association - COSMIC cancer census association via MalaCards
Search RARG in MalaCards View complete list of genes associated with diseases

Additional Disease Information for RARG

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with RARG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for RARG Gene

Publications for RARG Gene

  1. Genomic organization of the retinoic acid receptor gamma gene. (PMID: 1849262) Lehmann JM … Pfahl M (Nucleic acids research 1991) 2 3 4 23
  2. Murine isoforms of retinoic acid receptor gamma with specific patterns of expression. (PMID: 2157210) Kastner P … Chambon P (Proceedings of the National Academy of Sciences of the United States of America 1990) 3 4 23
  3. Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes. (PMID: 19902255) Ovsyannikova IG … Poland GA (Human genetics 2010) 3 41
  4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
  5. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PMID: 20634891) Jugessur A … Murray JC (PloS one 2010) 3 41

ExternalLinks

View latest publications for RARG gene in Mastermind

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