Aliases for RANBP1 Gene
External Ids for RANBP1 Gene
Previous GeneCards Identifiers for RANBP1 Gene
This gene encodes a protein that forms a complex with Ras-related nuclear protein (Ran) and metabolizes guanoside triphosphate (GTP). This complex participates in the regulation of the cell cycle by controlling transport of proteins and nucleic acids into the nucleus. There are multiple pseudogenes for this gene on chromosomes 9, 12, 17, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for RANBP1 Gene
RANBP1 (RAN Binding Protein 1) is a Protein Coding gene. Diseases associated with RANBP1 include Velocardiofacial Syndrome. Among its related pathways are E2F transcription factor network and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and GDP-dissociation inhibitor activity.
UniProtKB/Swiss-Prot for RANBP1 Gene
Inhibits GTP exchange on Ran. Forms a Ran-GTP-RANBP1 trimeric complex. Increase GTP hydrolysis induced by the Ran GTPase activating protein RANGAP1. May act in an intracellular signaling pathway which may control the progression through the cell cycle by regulating the transport of protein and nucleic acids across the nuclear membrane.