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This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [pro... See more...
Aliases for RALGAPA1 Gene
Aliases for RALGAPA1 Gene
- P240 3 4
- Ral GTPase Activating Protein, Alpha Subunit 1 (Catalytic) 3
- Ral GTPase Activating Protein Catalytic Alpha Subunit 1 3
- GTPase-Activating Rap/Ran-GAP Domain-Like 1 4
- GTPase Activating RANGAP Domain-Like 1 2
- GAP-Related-Interacting Partner To E12 4
- DKFZp667F074 2
- RALGAPA1 5
- NEDHRIT 3
- Tulip1 2
External Ids for RALGAPA1 Gene
- HGNC: 17770
- Entrez Gene: 253959
- Ensembl: ENSG00000174373
- OMIM: 608884
- UniProtKB: Q6GYQ0
Previous HGNC Symbols for RALGAPA1 Gene
- GARNL1
Previous GeneCards Identifiers for RALGAPA1 Gene
- GC14M035080
- GC14M036008
- GC14M016121
Summaries for RALGAPA1 Gene
-
This gene encodes a major subunit of the RAL-GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14-3-3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9. [provided by RefSeq, Oct 2016]
GeneCards Summary for RALGAPA1 Gene
RALGAPA1 (Ral GTPase Activating Protein Catalytic Subunit Alpha 1) is a Protein Coding gene. Diseases associated with RALGAPA1 include Neurodevelopmental Disorder With Hypotonia, Neonatal Respiratory Insufficiency, And Thermodysregulation and Newborn Respiratory Distress Syndrome. Among its related pathways are Integrated Breast Cancer Pathway. Gene Ontology (GO) annotations related to this gene include protein heterodimerization activity and GTPase activator activity. An important paralog of this gene is RALGAPA2.
UniProtKB/Swiss-Prot Summary for RALGAPA1 Gene
-
Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.
Additional gene information for RALGAPA1 Gene
- HGNC(17770)
- Entrez Gene(253959)
- Ensembl(ENSG00000174373)
- OMIM(608884)
- UniProtKB(Q6GYQ0)
- Open Targets Platform(ENSG00000174373)
- Monarch Initiative
- Search for RALGAPA1 at DataMed
- Search for RALGAPA1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RALGAPA1 Gene
Genomics for RALGAPA1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RALGAPA1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RALGAPA1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RALGAPA1
Genomic Locations for RALGAPA1 Gene
Genomic Locations for RALGAPA1 Gene
- chr14:35,538,352-35,809,304
- (GRCh38/hg38)
- Size:
- 270,953 bases
- Orientation:
- Minus strand
- chr14:36,007,558-36,278,510
- (GRCh37/hg19)
- Size:
- 270,953 bases
- Orientation:
- Minus strand
Genomic View for RALGAPA1 Gene
Genes around RALGAPA1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q13.2 by HGNC
- 14q13.2 by Entrez Gene
- 14q13.2 by Ensembl
RALGAPA1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RALGAPA1 Gene
Proteins for RALGAPA1 Gene
-
Protein details for RALGAPA1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q6GYQ0-RGPA1_HUMAN
- Recommended name:
- Ral GTPase-activating protein subunit alpha-1
- Protein Accession:
- Q6GYQ0
- A6NMA4
- B9EK38
- C5NU19
- O94960
- Q6GYP9
- Q6ZT23
- Q86YF3
- Q86YF5
- Q8ND69
Protein attributes for RALGAPA1 Gene
- Size:
- 2036 amino acids
- Molecular mass:
- 229832 Da
- Quaternary structure:
-
- Component of the heterodimeric RalGAP1 complex with RALGAPB. Heterodimerization is required for activity. Interacts with the HLH region of TCF3/isoform E12 (By similarity).
- SequenceCaution:
-
- Sequence=BAC86772.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for RALGAPA1 Gene
Post-translational modifications for RALGAPA1 Gene
Other Protein References for RALGAPA1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- XP_005267549.1
- XP_005267555.1
- XP_006720161.1
- XP_006720162.1
- XP_006720163.1
- XP_006720164.1
- XP_006720167.1
- XP_011534917.1
- XP_011534918.1
- XP_016876632.1
- XP_016876635.1
- XP_016876636.1
- XP_024305291.1
- NP_001269972.1
- NP_001269973.1
- NP_001317004.1
- NP_001333172.1
- NP_001333174.1
- NP_001333175.1
- NP_001333176.1
- NP_001333177.1
- NP_001333178.1
- NP_055805.1
- NP_919277.2
Antibody Products
- G Biosciences Immunotag™ RALGAPA1 Antibody
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-
Abcam antibodies for RALGAPA1
- Invitrogen Antibodies for RALGAPA1 (AFLGC-RALGAPA1)
-
Boster Bio Antibodies for RALGAPA1
-
Santa Cruz Biotechnology (SCBT) Antibodies for RALGAPA1
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RALGAPA1
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- Novus Biologicals proteins for RALGAPA1
- antibodies-online: Show 3 available RALGAPA1 Proteins ranked by validation data
- Compare Top RALGAPA1 Proteins
-
Quality Products:
-
Abcam proteins for RALGAPA1
No data available for DME Specific Peptides for RALGAPA1 Gene
Domains & Families for RALGAPA1 Gene
Gene Families for RALGAPA1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for RALGAPA1 Gene
- InterPro:
- Blocks:
-
- Rap/ran-GAP
- ProtoNet:
Suggested Antigen Peptide Sequences for RALGAPA1 Gene
- GenScript: Design optimal peptide antigens:
-
- GARNL1 protein (A0PJ59_HUMAN)
- p240 (RGPA1_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RALGAPA1 Gene
Function for RALGAPA1 Gene
Molecular function for RALGAPA1 Gene
- UniProtKB/Swiss-Prot Function:
- Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.
Phenotypes From GWAS Catalog for RALGAPA1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IBA,ISS | -- |
| GO:0046982 | protein heterodimerization activity | IPI | 19520869 |
Phenotypes for RALGAPA1 Gene
- GenomeRNAi human phenotypes for RALGAPA1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RALGAPA1 - Select products 50% OFF >
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miRNA for RALGAPA1 Gene
- miRTarBase miRNAs that target RALGAPA1
-
- hsa-miR-17-5p (MIRT051044)
- hsa-miR-4659b-3p (MIRT662431)
- hsa-miR-4659a-3p (MIRT662432)
- hsa-miR-6875-3p (MIRT662433)
- hsa-miR-6868-3p (MIRT662434)
- hsa-miR-2355-5p (MIRT662435)
- hsa-miR-361-5p (MIRT662436)
- hsa-miR-627-3p (MIRT662437)
- hsa-miR-4778-3p (MIRT662438)
- hsa-miR-1248 (MIRT662439)
- hsa-miR-1237-3p (MIRT662440)
- hsa-miR-2115-3p (MIRT662441)
- hsa-miR-3074-3p (MIRT662442)
- hsa-miR-4282 (MIRT662443)
miRNA Products
Inhibitory RNA Products
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Clone Products
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- Sino Biological Human cDNA Clone for RALGAPA1
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Cell Line Products
-
Horizon Cell Lines for RALGAPA1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RALGAPA1 Gene
Localization for RALGAPA1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RALGAPA1 Gene
- Cytoplasm. Nucleus. Note=Translocated to the nucleus, when associated with TCF3/E12. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 3 |
| mitochondrion | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| golgi apparatus | 1 |
- Cytosol (2)
- Mitochondria (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | ISS | -- |
| GO:0005737 | cytoplasm | IBA,ISS | -- |
Pathways & Interactions for RALGAPA1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Integrated Breast Cancer Pathway | ||
Pathways by source for RALGAPA1 Gene
1 BioSystems pathway for RALGAPA1 Gene
1 GeneTex pathway for RALGAPA1 Gene
Interacting Proteins for RALGAPA1 Gene
| Symbol | External ID(s) | Details |
|---|---|---|
| AGAP2 | ||
| DUSP23 | ||
| ENSG00000272822 | ||
| GFOD1 | ||
| MAPK3 |
GPS-Prot Interaction Network for RALGAPA1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0043547 | positive regulation of GTPase activity | IEA | -- |
| GO:0051056 | regulation of small GTPase mediated signal transduction | IEA | -- |
| GO:0090630 | activation of GTPase activity | ISS | -- |
No data available for SIGNOR curated interactions for RALGAPA1 Gene
Drugs & Compounds for RALGAPA1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| RBC8 | Pharma | 0 |
(1) ApexBio Compounds for RALGAPA1 Gene
| Compound | Action | Cas Number |
|---|---|---|
| RBC8 | 361185-42-4 |
Transcripts for RALGAPA1 Gene
mRNA/cDNA for RALGAPA1 Gene
- 11 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 19 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000307138 7911 nts (view in UCSC)
- ENST00000382366 6328 nts (view in UCSC)
- ENST00000389698 7864 nts (view in UCSC)
- ENST00000553892 6271 nts (view in UCSC)
- ENST00000553917 723 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RALGAPA1 - Select products 50% OFF >
- * RALGAPA1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RALGAPA1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RALGAPA1
-
Santa Cruz Biotechnology (SCBT) CRISPR for RALGAPA1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RALGAPA1
- Browse OriGene Inhibitory RNA Products For RALGAPA1
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Clone Products
- Applied Biological Materials (abm): Clones for RALGAPA1 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for RALGAPA1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RALGAPA1
Relevant External Links for RALGAPA1 Gene
- GeneLoc Exon Structure for
- RALGAPA1
Expression for RALGAPA1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Liver (23.4) and Esophagus (8.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RALGAPA1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RALGAPA1
SOURCE GeneReport for Unigene cluster for RALGAPA1 Gene:
Hs.113150mRNA Expression by UniProt/SwissProt for RALGAPA1 Gene:
Q6GYQ0-RGPA1_HUMAN
Tissue specificity:
Widely expressed.
Evidence on tissue expression from TISSUES for RALGAPA1 Gene
- Nervous system(4.6)
- Skin(4.4)
- Liver(4.3)
- Lymph node(4.1)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs for RALGAPA1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RALGAPA1 Gene
Orthologs for RALGAPA1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RALGAPA1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GARNL1 31 |
|
OneToOne | |
| RALGAPA1 30 |
|
||||
| Rat (Rattus norvegicus) |
Mammalia | Ralgapa1 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RALGAPA1 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Ralgapa1 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RALGAPA1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RALGAPA1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Zebrafish (Danio rerio) |
Actinopterygii | ralgapa1 30 31 |
|
OneToOne | |
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG5521 30 31 |
|
OneToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP004143 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | Y18H1A.3 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for RALGAPA1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
Evolution for RALGAPA1 Gene
- ENSEMBL:
- Gene Tree for RALGAPA1 (if available)
- TreeFam:
- Gene Tree for RALGAPA1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RALGAPA1: view image
Paralogs for RALGAPA1 Gene
(3) SIMAP similar genes for RALGAPA1 Gene using alignment to 4 proteins:
- RGPA1_HUMAN
- H0YJ04_HUMAN
- H0YJB5_HUMAN
- L8EAR6_HUMAN
Pseudogenes.org Pseudogenes for RALGAPA1 Gene
Variants for RALGAPA1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RALGAPA1 Gene
| SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 691794 | Pathogenic: Generalized hypotonia; Respiratory distress; Feeding difficulties; Infantile spasms; NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA, NEONATAL RESPIRATORY INSUFFICIENCY, AND THERMODYSREGULATION | 35,748,710(-) | G/A | NONSENSE | |
| 691795 | Pathogenic: Generalized hypotonia; Respiratory distress; Feeding difficulties; Infantile spasms; NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA, NEONATAL RESPIRATORY INSUFFICIENCY, AND THERMODYSREGULATION | 35,627,436(-) | TA/T | FRAMESHIFT_VARIANT | |
| 691796 | Pathogenic: Generalized hypotonia; Respiratory distress; Feeding difficulties; Infantile spasms; NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA, NEONATAL RESPIRATORY INSUFFICIENCY, AND THERMODYSREGULATION | 35,756,846(-) | C/A | NONSENSE | |
| 691797 | Pathogenic: Generalized hypotonia; Respiratory distress; Feeding difficulties; Infantile spasms; NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA, NEONATAL RESPIRATORY INSUFFICIENCY, AND THERMODYSREGULATION | 35,572,678(-) | G/C | NONSENSE | |
| 691798 | Pathogenic: Generalized hypotonia; Respiratory distress; Feeding difficulties; Infantile spasms; NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA, NEONATAL RESPIRATORY INSUFFICIENCY, AND THERMODYSREGULATION | 35,674,589(-) | T/C | MISSENSE_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2549342 | CNV | deletion | 19546169 |
| esv3307851 | CNV | mobile element insertion | 20981092 |
| esv3338357 | CNV | insertion | 20981092 |
| esv3634063 | CNV | loss | 21293372 |
| esv3634066 | CNV | loss | 21293372 |
| nsv1241 | CNV | insertion | 18451855 |
| nsv456206 | CNV | loss | 19166990 |
| nsv507742 | OTHER | sequence alteration | 20534489 |
| nsv525294 | CNV | loss | 19592680 |
| nsv564341 | CNV | loss | 21841781 |
| nsv564342 | CNV | loss | 21841781 |
| nsv564343 | CNV | loss | 21841781 |
| nsv976331 | CNV | duplication | 23825009 |
Residual Variation Intolerance Score:
7.94% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.80;
86.82% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RALGAPA1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RALGAPA1 Gene
Disorders for RALGAPA1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| neurodevelopmental disorder with hypotonia, neonatal respiratory insufficiency, and thermodysregulation |
|
|
| newborn respiratory distress syndrome |
|
|
| west syndrome |
|
|
| holoprosencephaly 8 |
|
|
| retinitis pigmentosa 42 |
|
|
Search RALGAPA1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RALGAPA1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RALGAPA1 Gene
Publications for RALGAPA1 Gene
- Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. (PMID: 19520869) Shirakawa R … Horiuchi H (The Journal of biological chemistry 2009) 2 3 4
- Cloning, genomic structure, and expression profiles of TULIP1 (GARNL1), a brain-expressed candidate gene for 14q13-linked neurological phenotypes, and its murine homologue. (PMID: 15498464) Schwarzbraun T … Petek E (Genomics 2004) 3 4 23
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
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- Browse Recombinant Antibodies
- Invitrogen Antibodies for RALGAPA1 (AFLGC-RALGAPA1)
- ApexBio compounds for RALGAPA1
- VectorBuilder Custom and pre-made DNA vectors for RALGAPA1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for RALGAPA1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for RALGAPA1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for RALGAPA1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RALGAPA1
- antibodies-online: Show 4 available RALGAPA1 Antibodies ranked by validation data
- Compare Top RALGAPA1 Antibodies
- antibodies-online: Search results for available RALGAPA1 related products ranked by validation data
- antibodies-online: Show 3 available RALGAPA1 Proteins ranked by validation data
- Compare Top RALGAPA1 Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for RALGAPA1
- Search Santa Cruz Biotechnology (SCBT) for RALGAPA1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RALGAPA1
- Horizon Cell Lines for RALGAPA1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RALGAPA1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RALGAPA1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RALGAPA1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RALGAPA1
- Boster Bio Antibodies for RALGAPA1
- Browse Boster Bio ELISA Kits
Sources for RALGAPA1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB