Aliases for RALBP1 Gene
Aliases for RALBP1 Gene
External Ids for RALBP1 Gene
- HGNC: 9841
- Entrez Gene: 10928
- Ensembl: ENSG00000017797
- OMIM: 605801
- UniProtKB: Q15311
Previous GeneCards Identifiers for RALBP1 Gene
- GC18P009629
Summaries for RALBP1 Gene
-
RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 [PubMed 12888294]).[supplied by OMIM, Nov 2010]
GeneCards Summary for RALBP1 Gene
RALBP1 (RalA Binding Protein 1) is a Protein Coding gene. Diseases associated with RALBP1 include Lung Cancer. Among its related pathways are EGF/EGFR Signaling Pathway and Cytoskeletal Signaling. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and Rac GTPase binding. An important paralog of this gene is ARHGAP32.
UniProtKB/Swiss-Prot for RALBP1 Gene
-
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Additional gene information for RALBP1 Gene
- Monarch Initiative
- Search for RALBP1 at DataMed
- Search for RALBP1 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for RALBP1 Gene
Genomics for RALBP1 Gene
GeneHancer (GH) Regulatory Elements for RALBP1 Gene
Promoters and enhancers for RALBP1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around RALBP1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the RALBP1 gene promoter:
-
- p53
- Sp1
- Pax-4a
- AP-2alpha
- AP-2alphaA
- AP-2beta
- AP-2gamma
- AREB6
Regulatory Element Products
Genomic Locations for RALBP1 Gene
Genomic Locations for RALBP1 Gene
- chr18:9,475,009-9,538,116
- (GRCh38/hg38)
- Size:
- 63,108 bases
- Orientation:
- Plus strand
- chr18:9,475,007-9,538,114
- (GRCh37/hg19)
- Size:
- 63,108 bases
- Orientation:
- Plus strand
Genomic View for RALBP1 Gene
Genes around RALBP1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 18p11.22 by Entrez Gene
- 18p11.22 by HGNC
- 18p11.22 by Ensembl
RALBP1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RALBP1 Gene
Proteins for RALBP1 Gene
-
Protein details for RALBP1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q15311-RBP1_HUMAN
- Recommended name:
- RalA-binding protein 1
- Protein Accession:
- Q15311
- D3DUI0
Protein attributes for RALBP1 Gene
- Size:
- 655 amino acids
- Molecular mass:
- 76063 Da
- Quaternary structure:
-
- Interacts with the GTP-bound form of RALA, RALB, CDC42 and RAC1. Interacts with REPS1 and REPS2 and this does not affect the Ral-binding activity. Interacts with DAB2IP. Interacts with catalytically active CCNB1 and CDK1 during mitosis. Interacts with EPN1, NUMB and TFAP2A during interphase and mitosis.
Protein Expression for RALBP1 Gene
Post-translational modifications for RALBP1 Gene
Other Protein References for RALBP1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for RALBP1
-
Abcam antibodies for RALBP1
- Invitrogen Antibodies for RALBP1
- GeneTex RALBP1 Antibody for RALBP1
-
Boster Bio Antibodies for RALBP1
-
Santa Cruz Biotechnology (SCBT) Antibodies for RALBP1
Protein Products
-
OriGene Purified Proteins for RALBP1
- Search Origene for MassSpec and Protein Over-expression Lysates for RALBP1
- Origene Custom Protein Services for RALBP1
- Search GeneTex for Proteins for RALBP1
Assay Products
- antibodies-online: Search results for 7 available RALBP1 Elisa Kits ranked by validation data
- Compare Top RALBP1 Elisa Kits
-
Quality Products:
-
Abcam assays for RALBP1
No data available for DME Specific Peptides for RALBP1 Gene
Domains & Families for RALBP1 Gene
Gene Families for RALBP1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Transporters
Protein Domains for RALBP1 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for RALBP1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for RALBP1 Gene
Function for RALBP1 Gene
Molecular function for RALBP1 Gene
- UniProtKB/Swiss-Prot Function:
- Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 9422736 |
| GO:0015238 | drug transmembrane transporter activity | IDA | 10924126 |
| GO:0016887 | ATPase activity | IBA | -- |
| GO:0017160 | Ral GTPase binding | IPI | 7673236 |
Phenotypes for RALBP1 Gene
- MGI mutant phenotypes for RALBP1:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for RALBP1:
Animal Model Products
-
Taconic Biosciences Mouse Models for RALBP1
- Cyagen custom Knockout/knockin (KOKI) mouse models for RALBP1
-
CRISPR Products
-
OriGene CRISPR knockouts for RALBP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RALBP1
- genomics-online: gRNA clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- Applied Biological Materials CRISPR for RALBP1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RALBP1
- GenScript: Design CRISPR guide RNA sequences for RALBP1
miRNA for RALBP1 Gene
- miRTarBase miRNAs that target RALBP1
-
- hsa-mir-1914-5p (MIRT035794)
- hsa-mir-615-3p (MIRT040266)
- hsa-mir-125a-5p (MIRT045735)
- hsa-mir-10b-5p (MIRT047496)
- hsa-mir-10a-5p (MIRT047750)
- hsa-mir-185-5p (MIRT738261)
- hsa-mir-298 (MIRT739544)
- hsa-mir-3150b-3p (MIRT740327)
- hsa-mir-3158-5p (MIRT740481)
- hsa-mir-4306 (MIRT743918)
- hsa-mir-4418 (MIRT744159)
- hsa-mir-4428 (MIRT744312)
- hsa-mir-4481 (MIRT745118)
- hsa-mir-4640-5p (MIRT746337)
- hsa-mir-4644 (MIRT746390)
- hsa-mir-4693-3p (MIRT747150)
- hsa-mir-4726-5p (MIRT747766)
- hsa-mir-4745-5p (MIRT748189)
- hsa-mir-4784 (MIRT748844)
- hsa-mir-509-3-5p (MIRT749676)
- hsa-mir-509-5p (MIRT749712)
- hsa-mir-5192 (MIRT749952)
- hsa-mir-6508-3p (MIRT752975)
- hsa-mir-6758-5p (MIRT754885)
- hsa-mir-6856-5p (MIRT757731)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for RALBP1
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RALBP1
- genomics-online: shRNA clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for RALBP1
- VectorBuilder custom plasmid, inducible vectors for RALBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RALBP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RALBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RALBP1
- Applied Biological Materials Clones for RALBP1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for RALBP1
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RALBP1 Gene
Localization for RALBP1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for RALBP1 Gene
- Membrane; Peripheral membrane protein.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| endosome | 2 |
- Cytosol (2)
- Nuclear membrane (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0016020 | membrane | IDA,IEA | 10924126 |
Pathways & Interactions for RALBP1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Doxorubicin Pathway, Pharmacokinetics | ||
| 2 | Endometrial cancer | ||
| 3 | Pathways in cancer | ||
| 4 | Ras signaling pathway | ||
| 5 | Phenytoin Pathway, Pharmacokinetics | ||
Pathways by source for RALBP1 Gene
2 GeneTex pathways for RALBP1 Gene
4 BioSystems pathways for RALBP1 Gene
3 Reactome pathways for RALBP1 Gene
3 KEGG pathways for RALBP1 Gene
5 GeneGo (Thomson Reuters) pathways for RALBP1 Gene
3 Qiagen pathways for RALBP1 Gene
1 Cell Signaling Technology pathway for RALBP1 Gene
Interacting Proteins for RALBP1 Gene
Selected Interacting proteins:
Q15311-RBP1_HUMAN
ENSP00000019317
for RALBP1 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for RALBP1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006855 | drug transmembrane transport | IDA | 10924126 |
| GO:0006897 | endocytosis | IBA | -- |
| GO:0006935 | chemotaxis | TAS | 10848592 |
| GO:0007165 | signal transduction | IEA,TAS | 7673236 |
| GO:0007264 | small GTPase mediated signal transduction | IPI | 7673236 |
No data available for SIGNOR curated interactions for RALBP1 Gene
Drugs & Compounds for RALBP1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Doxorubicin | Approved, Investigational | Pharma | Transporter, substrate | Topo II inhibitor,immunosuppresive antineoplastic antibiotic | 1828 | |
| Carbamazepine | Approved, Investigational | Pharma | Transporter, substrate | Inhibitor of neuronal voltage-gated Na+ channels; anticonvulsant | 134 | |
| Sorafenib | Approved, Investigational | Pharma | Transporter, substrate | Raf kinases and tyrosine kinases inhibitor, RAF, VEGFR2, and PDGFR-beta inhibitors, Kinase Inhibitors, Vascular endothelial growth factor (VEGF) and VEGF receptor (VEGFR) inhibitors | 717 | |
| Vincristine | Approved, Investigational | Pharma | Transporter, substrate | Microtubule disrupter,antitumor agent | 965 | |
| Doxil | Approved June 1999 | Pharma | DNA intercalator and TOPO II inhibitor, Topoisomerase 2 Inhibitors | 1828 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
Transcripts for RALBP1 Gene
mRNA/cDNA for RALBP1 Gene
- (1) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (300) Selected AceView cDNA sequences:
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000019317 4368 bps (uc002kob.4)
- ENST00000585015 945 bps (uc060ngd.1)
- ENST00000609094 3676 bps (uc060ngh.1)
- ENST00000383432 4224 bps (uc002koc.4)
- ENST00000458039 836 bps (uc060nge.1)
Unigene Clusters for RALBP1 Gene
- RalA binding protein 1:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for RALBP1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RALBP1
- genomics-online: gRNA clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- Applied Biological Materials CRISPR for RALBP1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for RALBP1
- GenScript: Design CRISPR guide RNA sequences for RALBP1
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for RALBP1
- Browse OriGene Inhibitory RNA Products For RALBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RALBP1
- genomics-online: shRNA clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for RALBP1
- VectorBuilder custom plasmid, inducible vectors for RALBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RALBP1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RALBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RALBP1
- Applied Biological Materials Clones for RALBP1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - | - |
Expression for RALBP1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Granulocytes Peripheral Blood
This gene is overexpressed in Peripheral blood mononuclear cells (11.8) and Retina (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RALBP1 Gene
NURSA nuclear receptor signaling pathways regulating expression of RALBP1 Gene:
RALBP1SOURCE GeneReport for Unigene cluster for RALBP1 Gene:
Hs.528993mRNA Expression by UniProt/SwissProt for RALBP1 Gene:
Q15311-RBP1_HUMAN
Tissue specificity:
Expressed ubiquitously but at low levels. Shows a strong expression in the erythrocytes.
Evidence on tissue expression from TISSUES for RALBP1 Gene
- Liver(4.4)
- Nervous system(4.4)
- Blood(4.3)
- Bone marrow(4.2)
- Kidney(2.2)
- Lung(2.1)
- Heart(2)
- Intestine(2)
- Muscle(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for RALBP1
-
OriGene qPCR primer pairs for RALBP1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for RALBP1 Gene
Orthologs for RALBP1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | RALBP1 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | RALBP1 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| oppossum (Monodelphis domestica) |
Mammalia | RALBP1 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Ralbp1 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ralbp1 33 |
|
||
| cow (Bos Taurus) |
Mammalia | RALBP1 34 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | RALBP1 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | RALBP1 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ralbp1 33 |
|
||
| Str.11420 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | rlip1-A-prov 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ralbp1 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Rlip 34 35 |
|
OneToOne | |
| worm (Caenorhabditis elegans) |
Secernentea | rlbp-1 34 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RGD1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for RALBP1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for RALBP1 Gene
- ENSEMBL:
- Gene Tree for RALBP1 (if available)
- TreeFam:
- Gene Tree for RALBP1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RALBP1: view image
Paralogs for RALBP1 Gene
Paralogs for RALBP1 Gene
(1) SIMAP similar genes for RALBP1 Gene using alignment to 3 proteins:
- RBP1_HUMAN
- E7ENF8_HUMAN
- J3QLT3_HUMAN
Pseudogenes.org Pseudogenes for RALBP1 Gene
Variants for RALBP1 Gene
| SNP ID | Clin | Chr 18 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000089842 | -- | 9,512,804(+) | G/C/T | intron_variant | |
| rs1000091799 | -- | 9,498,484(+) | C/T | intron_variant | |
| rs1000115058 | -- | 9,487,584(+) | A/G | intron_variant | |
| rs1000146629 | -- | 9,529,070(+) | A/G | intron_variant | |
| rs1000229096 | -- | 9,509,604(+) | C/A/T | intron_variant |
Residual Variation Intolerance Score:
14.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.88;
35.08% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RALBP1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RALBP1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RALBP1 Gene
Disorders for RALBP1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lung cancer |
|
Search RALBP1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RALBP1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for RALBP1 Gene
Publications for RALBP1 Gene
- Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity. (PMID: 7673236) Jullien-Flores V … Camonis JH (The Journal of biological chemistry 1995) 2 3 4 22 58
- The association between polymorphisms in RLIP76 and drug response in epilepsy. (PMID: 18086001) Leschziner GD … Pirmohamed M (Pharmacogenomics 2007) 3 22 44 58
- RLIP76 is the major ATP-dependent transporter of glutathione-conjugates and doxorubicin in human erythrocytes. (PMID: 11437348) Sharma R … Awasthi YC (Archives of biochemistry and biophysics 2001) 3 4 22 58
- Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin. (PMID: 10924126) Awasthi S … Awasthi YC (Biochemistry 2000) 3 4 22 58
- Rlip76 transports sunitinib and sorafenib and mediates drug resistance in kidney cancer. (PMID: 19626587) Singhal SS … Awasthi S (International journal of cancer 2010) 3 22 58
Products for RALBP1 Gene
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- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for RALBP1
- Novus Biologicals lysates and proteins for RALBP1
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for RALBP1
- Abcam assays for RALBP1
- Find your target
- Browse Primary Antibodies
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- Browse ELISA Kits
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for RALBP1
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for RALBP1
- Cyagen custom Knockout/knockin (KOKI) mouse models for RALBP1
- VectorBuilder custom plasmid, inducible vectors for RALBP1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for RALBP1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for RALBP1
- antibodies-online: Search results for 120 available RALBP1 Antibodies ranked by validation data
- Compare Top RALBP1 Antibodies
- antibodies-online: Search results for 7 available RALBP1 Elisa Kits ranked by validation data
- Compare Top RALBP1 Elisa Kits
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- antibodies-online: Search results for 14 available RALBP1 Proteins ranked by validation data
- Compare Top RALBP1 Proteins
- GeneTex RALBP1 Antibody for RALBP1
- Search GeneTex for Proteins for RALBP1
- Santa Cruz Biotechnology (SCBT) Antibodies for RALBP1
- Search Santa Cruz Biotechnology (SCBT) for RALBP1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RALBP1
- Horizon Cell Lines for RALBP1
- genomics-online: cdna clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- orf clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- genomics-online: gRNA clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- genomics-online: primer clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- genomics-online: shRNA clones - Search results for 118 available RALBP1 gene related products
- Overview of 118 available RALBP1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RALBP1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RALBP1
- GeneCopoeia miRNA 3'UTR Target clone products for RALBP1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RALBP1
- Boster Bio Antibodies for RALBP1
- Browse Boster Bio ELISA Kits
Sources for RALBP1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt