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Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this retinoic acid-induced gene has not yet been determined but it may play a role in development. The chromosomal location of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked cogniti... See more...
Aliases for RAI2 Gene
External Ids for RAI2 Gene
- HGNC: 9835
- Entrez Gene: 10742
- Ensembl: ENSG00000131831
- OMIM: 300217
- UniProtKB: Q9Y5P3
Previous GeneCards Identifiers for RAI2 Gene
- GC0XM017362
- GC0XM016484
- GC0XM017020
- GC0XM017179
- GC0XM017578
- GC0XM017728
- GC0XM015576
Summaries for RAI2 Gene
-
Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this retinoic acid-induced gene has not yet been determined but it may play a role in development. The chromosomal location of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked cognitive disability, oral-facial-digital syndrome, and Fried syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
GeneCards Summary for RAI2 Gene
RAI2 (Retinoic Acid Induced 2) is a Protein Coding gene. Diseases associated with RAI2 include Nance-Horan Syndrome and Dextrocardia. Among its related pathways are Neuroscience. An important paralog of this gene is SOBP.
Additional gene information for RAI2 Gene
- HGNC(9835)
- Entrez Gene(10742)
- Ensembl(ENSG00000131831)
- OMIM(300217)
- UniProtKB(Q9Y5P3)
- Open Targets Platform(ENSG00000131831)
- Search for RAI2 at DataMed
- Search for RAI2 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RAI2 Gene
Genomics for RAI2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RAI2 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH0XJ017859 | Promoter/Enhancer | 1.4 | EPDnew Ensembl ENCODE | 600.7 | +0.8 | 845 | 2.6 | PRDM10 ZSCAN4 POLR2A PATZ1 EZH2 ZNF341 ZBTB20 SP2 RAD21 ZBTB10 | RAI2 lnc-BEND2-2 SCML1 | |
| GH0XJ017412 | Enhancer | 0.9 | ENCODE | 20.9 | +446.9 | 446864 | 4.5 | PRDM10 ZNF629 RFX1 ZNF692 PRDM1 ZSCAN4 PATZ1 IKZF2 ZNF148 CEBPB | RAI2 NHS CTPS2 TXLNG SCML1 RBBP7 RF00017-8185 piR-43105-686 | |
| GH0XJ017793 | Enhancer | 0.2 | Ensembl | 11.9 | +67.8 | 67845 | 0.6 | RAI2 SCML1 piR-46002-602 lnc-BEND2-2 | ||
| GH0XJ017735 | Promoter/Enhancer | 2.3 | UCNEbase EPDnew Ensembl ENCODE CraniofacialAtlas | 0.1 | +123.3 | 123265 | 5.8 | SP1 CREB1 GATAD2A PRDM10 ZNF629 KDM1A ZNF692 RCOR2 TARDBP FOXA1 | SCML1 lnc-RAI2-5 HSALNG0136860 RAI2 NHS | |
| GH0XJ017809 | Enhancer | 0.7 | Ensembl | 0.2 | +51.7 | 51745 | 0.8 | ZIC2 ZSCAN4 ZNF561 TCF7L2 ZXDB OSR2 ZNF580 ZNF423 SCRT1 ZBTB11 | piR-46002-602 lnc-BEND2-2 RAI2 SCML1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RAI2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RAI2
- Top Transcription factor binding sites by QIAGEN in the RAI2 gene promoter:
-
- C/EBPbeta
- CUTL1
- E2F-1
- FOXI1
- HFH-3
- HNF-1
- HNF-1A
- Lmo2
- RORalpha1
- Sox5
Genomic Locations for RAI2 Gene
Genomic Locations for RAI2 Gene
- chrX:17,800,049-17,861,346
- (GRCh38/hg38)
- Size:
- 61,298 bases
- Orientation:
- Minus strand
- chrX:17,818,169-17,879,457
- (GRCh37/hg19)
- Size:
- 61,289 bases
- Orientation:
- Minus strand
Genomic View for RAI2 Gene
Genes around RAI2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.13 by HGNC
- Xp22.13 by Entrez Gene
- Xp22.13 by Ensembl
RAI2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RAI2 Gene
Proteins for RAI2 Gene
-
Protein details for RAI2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y5P3-RAI2_HUMAN
- Recommended name:
- Retinoic acid-induced protein 2
- Protein Accession:
- Q9Y5P3
- B1B1K2
- B4DQM9
- E7EMN4
- Q8N6X7
Protein attributes for RAI2 Gene
- Size:
- 530 amino acids
- Molecular mass:
- 57180 Da
- Quaternary structure:
- No Data Available
Protein Expression for RAI2 Gene
Post-translational modifications for RAI2 Gene
Other Protein References for RAI2 Gene
Antibody Products
- Creative Diagnostics Anti-RAI2 monoclonal antibody
- Creative Biolabs rabbit Anti-RAI2 Recombinant Antibody (D4W9P)
-
Custom Antibody ServicesOriGene Antibodies for RAI2
- Novus Biologicals Antibodies for RAI2
-
Abcam antibodies for RAI2
- Invitrogen Antibodies for RAI2 (AFLGC-RAI2)
- antibodies-online: Show 11 available RAI2 Antibodies ranked by validation data
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-
Quality Products:
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for RAI2
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- antibodies-online: Show 5 available RAI2 Proteins ranked by validation data
- Compare Top RAI2 Proteins
-
Quality Products:
-
Abcam proteins for RAI2
No data available for DME Specific Peptides for RAI2 Gene
Domains & Families for RAI2 Gene
Gene Families for RAI2 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for RAI2 Gene
- GenScript: Design optimal peptide antigens:
-
- Retinoic acid-induced protein 2 (RAI2_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for RAI2 Gene
Function for RAI2 Gene
Molecular function for RAI2 Gene
- GENATLAS Biochemistry:
- retinoic acid induced 2,expressed in heart,brain,placenta,lung,skeletal muscle,kidney,pancreas and retina,excluded as causing-disease gene in Nance-Horan syndrome
Phenotypes From GWAS Catalog for RAI2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003674 | molecular_function | ND | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
Phenotypes for RAI2 Gene
- MGI mutant phenotypes for RAI2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RAI2:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RAI2 - Select products 50% OFF >
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-
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-
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miRNA for RAI2 Gene
- miRTarBase miRNAs that target RAI2
miRNA Products
Inhibitory RNA Products
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Clone Products
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- MG208484
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- RC206638
- RC206638L3
- RC206638L4
- RC230148
- RC230148L3
- RC230148L4
- RC230235
- RC230235L3
- RC230235L4
- RC230236
- RC230236L3
- RC230236L4
- RG206638
- RG230148
- RG230235
- RG230236
- RR213516
- RR213516L3
- RR213516L4
- MR208484L3V
- MR208484L4V
- MR215708L3V
- MR215708L4V
- RC206638L3V
- RC206638L4V
- RC230148L3V
- RC230148L4V
- RC230235L3V
- RC230235L4V
- RC230236L3V
- RC230236L4V
- RR213516L3V
- RR213516L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RAI2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RAI2
Cell Line Products
-
Horizon Cell Lines for RAI2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for RAI2 Gene
Localization for RAI2 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 2 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| peroxisome | 0 |
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005575 | cellular_component | ND | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for RAI2 Gene
Pathways & Interactions for RAI2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Neuroscience | ||
Pathways by source for RAI2 Gene
1 Cell Signaling Technology pathway for RAI2 Gene
Interacting Proteins for RAI2 Gene
Selected Interacting proteins:
Q9Y5P3-RAI2_HUMAN
ENSP00000444210
for RAI2 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RAI2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0009792 | embryo development ending in birth or egg hatching | NAS | 10049581 |
No data available for SIGNOR curated interactions for RAI2 Gene
Transcripts for RAI2 Gene
mRNA/cDNA for RAI2 Gene
- 4 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000331511 2317 nts (view in UCSC)
- ENST00000360011 2377 nts (view in UCSC)
- ENST00000415486 2037 nts (view in UCSC)
- ENST00000451717 2187 nts (view in UCSC)
- ENST00000509491 463 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RAI2 - Select products 50% OFF >
- * RAI2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for RAI2
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-
Santa Cruz Biotechnology (SCBT) CRISPR for RAI2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RAI2
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RAI2
Clone Products
- Applied Biological Materials (abm): Clones for RAI2 - Select products 50% OFF >
- * RAI2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG208484
- MG215708
- MR208484
- MR208484L3
- MR208484L4
- MR215708
- MR215708L3
- MR215708L4
- RC206638
- RC206638L3
- RC206638L4
- RC230148
- RC230148L3
- RC230148L4
- RC230235
- RC230235L3
- RC230235L4
- RC230236
- RC230236L3
- RC230236L4
- RG206638
- RG230148
- RG230235
- RG230236
- RR213516
- RR213516L3
- RR213516L4
- MR208484L3V
- MR208484L4V
- MR215708L3V
- MR215708L4V
- RC206638L3V
- RC206638L4V
- RC230148L3V
- RC230148L4V
- RC230235L3V
- RC230235L4V
- RC230236L3V
- RC230236L4V
- RR213516L3V
- RR213516L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for RAI2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RAI2
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||
| SP6: | - | - | - | - |
Relevant External Links for RAI2 Gene
- GeneLoc Exon Structure for
- RAI2
Expression for RAI2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Metanephric Mesenchyme Cells Metanephric Mesenchyme
-
Blood (Hematopoietic System)
- Hematopoietic Stem Cells Hematopoietic Bone Marrow
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for RAI2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RAI2
SOURCE GeneReport for Unigene cluster for RAI2 Gene:
Hs.446680Evidence on tissue expression from TISSUES for RAI2 Gene
- Lung(4.2)
- Nervous system(2.3)
Primer Products
-
OriGene qPCR primer pairs for RAI2
-
OriGene qPCR primer pairs and template standards for RAI2
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for RAI2 Gene
Orthologs for RAI2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RAI2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RAI2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rai2 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rai2 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | RAI2 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | RAI2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RAI2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RAI2 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rai2 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC101885820 30 |
|
||
| RAI2 31 |
|
OneToOne |
- Species where no ortholog for RAI2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for RAI2 Gene
- ENSEMBL:
- Gene Tree for RAI2 (if available)
- TreeFam:
- Gene Tree for RAI2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RAI2: view image
Paralogs for RAI2 Gene
Variants for RAI2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RAI2 Gene
| SNP ID | Clinical significance and condition | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 719850 | Benign: not provided | 17,800,748(-) | T/C | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 727508 | Benign: not provided | 17,801,789(-) | C/T | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT,INTRON_VARIANT | |
| 737181 | Likely Benign: not provided | 17,801,480(-) | C/A | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 740738 | Likely Benign: not provided | 17,800,625(-) | G/A | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 780685 | Benign: not provided | 17,801,238(-) | G/A | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv1144318 | CNV | deletion | 24896259 |
Residual Variation Intolerance Score:
76% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.96;
19.88% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RAI2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- RAI2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAI2 Gene
Disorders for RAI2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| nance-horan syndrome |
|
|
| dextrocardia |
|
|
| colon lymphoma |
|
|
| decubitus ulcer |
|
|
| chronic ulcer of skin |
|
|
Search RAI2 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RAI2
No data available for UniProtKB/Swiss-Prot and Genatlas for RAI2 Gene
Publications for RAI2 Gene
- Identification and characterization of the human homologue (RAI2) of a mouse retinoic acid-induced gene in Xp22. (PMID: 10049581) Walpole SM … Trump D (Genomics 1999) 2 3 4
- Exclusion of RAI2 as the causative gene for Nance-Horan syndrome. (PMID: 10394933) Walpole SM … Toutain A (Human genetics 1999) 2 3 23
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
ExternalLinks
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- OriGene qPCR primer pairs for RAI2
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- MG208484
- MG215708
- MR208484
- MR208484L3
- MR208484L4
- MR215708
- MR215708L3
- MR215708L4
- RC206638
- RC206638L3
- RC206638L4
- RC230148
- RC230148L3
- RC230148L4
- RC230235
- RC230235L3
- RC230235L4
- RC230236
- RC230236L3
- RC230236L4
- RG206638
- RG230148
- RG230235
- RG230236
- RR213516
- RR213516L3
- RR213516L4
- MR208484L3V
- MR208484L4V
- MR215708L3V
- MR215708L4V
- RC206638L3V
- RC206638L4V
- RC230148L3V
- RC230148L4V
- RC230235L3V
- RC230235L4V
- RC230236L3V
- RC230236L4V
- RR213516L3V
- RR213516L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- antibodies-online: Show 11 available RAI2 Antibodies ranked by validation data
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- antibodies-online: Show 5 available RAI2 Proteins ranked by validation data
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RAI2
Sources for RAI2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB