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The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which sugg... See more...
Aliases for RAD54B Gene
Aliases for RAD54B Gene
External Ids for RAD54B Gene
- HGNC: 17228
- Entrez Gene: 25788
- Ensembl: ENSG00000197275
- OMIM: 604289
- UniProtKB: Q9Y620
Previous GeneCards Identifiers for RAD54B Gene
- GC08M094130
- GC08M095230
- GC08M095052
- GC08M095340
- GC08M095453
- GC08M095384
- GC08M090593
Summaries for RAD54B Gene
-
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]
GeneCards Summary for RAD54B Gene
RAD54B (RAD54 Homolog B) is a Protein Coding gene. Diseases associated with RAD54B include Lymphoma, Non-Hodgkin, Familial and Colorectal Cancer. Among its related pathways are Resolution of D-loop Structures through Holliday Junction Intermediates. Gene Ontology (GO) annotations related to this gene include hydrolase activity and RNA helicase activity. An important paralog of this gene is RAD54L.
UniProtKB/Swiss-Prot Summary for RAD54B Gene
-
Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
Additional gene information for RAD54B Gene
- HGNC(17228)
- Entrez Gene(25788)
- Ensembl(ENSG00000197275)
- OMIM(604289)
- UniProtKB(Q9Y620)
- Open Targets Platform(ENSG00000197275)
- Monarch Initiative
- Search for RAD54B at DataMed
- Search for RAD54B at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for RAD54B Gene
Genomics for RAD54B Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for RAD54B Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around RAD54B on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for RAD54B
- Top Transcription factor binding sites by QIAGEN in the RAD54B gene promoter:
-
- aMEF-2
- AML1a
- Evi-1
- FOXJ2
- FOXJ2 (long isoform)
- GATA-1
- MEF-2
- MEF-2A
- Pbx1a
- POU2F1a
Genomic Locations for RAD54B Gene
Genomic Locations for RAD54B Gene
- chr8:94,371,960-94,475,115
- (GRCh38/hg38)
- Size:
- 103,156 bases
- Orientation:
- Minus strand
- chr8:95,384,188-95,487,343
- (GRCh37/hg19)
- Size:
- 103,156 bases
- Orientation:
- Minus strand
Genomic View for RAD54B Gene
Genes around RAD54B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q22.1 by HGNC
- 8q22.1 by Entrez Gene
- 8q22.1 by Ensembl
RAD54B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for RAD54B Gene
Proteins for RAD54B Gene
-
Protein details for RAD54B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y620-RA54B_HUMAN
- Recommended name:
- DNA repair and recombination protein RAD54B
- Protein Accession:
- Q9Y620
- F6WBS8
Protein attributes for RAD54B Gene
- Size:
- 910 amino acids
- Molecular mass:
- 102967 Da
- Quaternary structure:
-
- Interacts with RAD51 through the NH2-terminal domain. Immunoprecipitation experiments show that the interaction is constitutive and not induced by ionizing radiation. The interaction may be indirect.
Protein Expression for RAD54B Gene
Selected DME Specific Peptides for RAD54B Gene
- Q9Y620:
-
- GTIEEKI
- IYRLLTT
- DEMGLGKT
- KEFQKWL
- GGVGLNL
- MGLGKTL
- RVWRDGQK
Post-translational modifications for RAD54B Gene
Other Protein References for RAD54B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ RAD54B Antibody
- Novus Biologicals Antibodies for RAD54B
-
Abcam antibodies for RAD54B
- Invitrogen Antibodies for RAD54B (AFLGC-RAD54B)
-
Biorbyt antibodies for RAD54B
-
Boster Bio Antibodies for RAD54B
-
Santa Cruz Biotechnology (SCBT) Antibodies for RAD54B
- Sino Biological Antibodies for RAD54B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for RAD54B
- Origene Custom Protein Services for RAD54B
- antibodies-online: Show 4 available RAD54B Proteins ranked by validation data
- Compare Top RAD54B Proteins
-
Quality Products:
Domains & Families for RAD54B Gene
Gene Families for RAD54B Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for RAD54B Gene
- InterPro:
- Blocks:
-
- SNF2 related domain
- ProtoNet:
Suggested Antigen Peptide Sequences for RAD54B Gene
- GenScript: Design optimal peptide antigens:
-
- RAD54 homolog B (RA54B_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y620- Family:
-
- Belongs to the SNF2/RAD54 helicase family.
Function for RAD54B Gene
Molecular function for RAD54B Gene
- UniProtKB/Swiss-Prot Function:
- Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
- GENATLAS Biochemistry:
- yeast (S cerevisiae) RAD54 homolog,recombination gene,highly expressed in testis and spleen,homozygously mutated in primary lymphoma and colon cancer
Enzyme Numbers (IUBMB) for RAD54B Gene
Phenotypes From GWAS Catalog for RAD54B Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003678 | DNA helicase activity | TAS | 10362364 |
| GO:0003724 | RNA helicase activity | TAS | 10362364 |
| GO:0004386 | helicase activity | IEA | -- |
Phenotypes for RAD54B Gene
- MGI mutant phenotypes for RAD54B:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for RAD54B:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased viability
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- Increased viability with MLN4924 (a NAE inhibitor)
- Resistant to vaccinia virus (VACV-A4L) infection
- Decreased vaccinia virus (VACV) infection
- Decreased human papilloma virus 16 (HPV16) pseudovirus infection
- Upregulation of Wnt pathway
- Decreased ionizing radiation sensitivity
Animal Models for RAD54B Gene
- MGI Knock Outs for RAD54B:
-
- Rad54b Rad54b<tm1Roka>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RAD54B - Select products 50% OFF >
- * RAD54B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for RAD54B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RAD54B
-
Santa Cruz Biotechnology (SCBT) CRISPR for RAD54B
miRNA for RAD54B Gene
- miRTarBase miRNAs that target RAD54B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RAD54B
- Browse OriGene Inhibitory RNA Products For RAD54B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RAD54B
Clone Products
- Applied Biological Materials (abm): Clones for RAD54B - Select products 50% OFF >
- * RAD54B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RAD54B
- Addgene plasmids for RAD54B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RAD54B
Cell Line Products
-
Horizon Cell Lines for RAD54B
No data available for Transcription Factor Targets and HOMER Transcription for RAD54B Gene
Localization for RAD54B Gene
Subcellular locations from UniProtKB/Swiss-Prot for RAD54B Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytosol | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for RAD54B Gene
Pathways & Interactions for RAD54B Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Resolution of D-loop Structures through Holliday Junction Intermediates | ||
Pathways by source for RAD54B Gene
1 BioSystems pathway for RAD54B Gene
1 KEGG pathway for RAD54B Gene
Interacting Proteins for RAD54B Gene
Selected Interacting proteins:
Q9Y620-RA54B_HUMAN
ENSP00000336606
for RAD54B Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for RAD54B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000724 | double-strand break repair via homologous recombination | IDA | 16428451 |
| GO:0006281 | DNA repair | IEA | -- |
| GO:0006312 | mitotic recombination | TAS | 10362364 |
| GO:0006974 | cellular response to DNA damage stimulus | IEA | -- |
| GO:0007131 | reciprocal meiotic recombination | TAS,IBA | 21873635 |
No data available for SIGNOR curated interactions for RAD54B Gene
Transcripts for RAD54B Gene
mRNA/cDNA for RAD54B Gene
- 5 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000297592 1879 nts (view in UCSC)
- ENST00000336148 3074 nts (view in UCSC)
- ENST00000463267 1699 nts (view in UCSC)
- ENST00000518358 583 nts (view in UCSC)
- ENST00000518998 599 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for RAD54B - Select products 50% OFF >
- * RAD54B CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for RAD54B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RAD54B
-
Santa Cruz Biotechnology (SCBT) CRISPR for RAD54B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for RAD54B
- Browse OriGene Inhibitory RNA Products For RAD54B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RAD54B
Clone Products
- Applied Biological Materials (abm): Clones for RAD54B - Select products 50% OFF >
- * RAD54B as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for RAD54B
- Addgene plasmids for RAD54B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RAD54B
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | ||||||||||||||||||||||||||||||||||||||
| SP6: |
Relevant External Links for RAD54B Gene
- GeneLoc Exon Structure for
- RAD54B
Expression for RAD54B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Adult Endothelial Cells Blood Brain Barrier
- Hypothalamus
- Pituitary Gland
- Thalamus
- Striatum
- Neural Tube (Nervous System)
-
Testis (Reproductive System)
- XY Germ Cells Testis Cord
-
Gonad
- XY Germ Cells Testis Cord
-
Endothelium (Cardiovascular System)
- Adult Endothelial Cells Blood Brain Barrier
- Kidney (Urinary System)
- Thymus (Hematopoietic System)
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for RAD54B Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for RAD54B
SOURCE GeneReport for Unigene cluster for RAD54B Gene:
Hs.744229mRNA Expression by UniProt/SwissProt for RAD54B Gene:
Q9Y620-RA54B_HUMAN
Tissue specificity:
Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon.
Phenotype-based relationships between genes and organs from Gene ORGANizer for RAD54B Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- immune
- reproductive
- urinary
Regions:
Abdomen:
- intestine
- kidney
- large intestine
- stomach
Pelvis:
- anus
- rectum
- ureter
- urethra
- urinary bladder
- uterus
General:
- blood
- white blood cell
Primer Products
-
OriGene qPCR primer pairs for RAD54B
-
OriGene qPCR primer pairs and template standards for RAD54B
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners and Evidence on tissue expression from TISSUES for RAD54B Gene
Orthologs for RAD54B Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | RAD54B 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | RAD54B 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | RAD54B 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Rad54b 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Rad54b 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | RAD54B 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | RAD54B 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | RAD54B 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | RAD54B 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rad54b 30 |
|
||
| Str.5565 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.32066 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | rad54b 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP006945 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | Y116A8C.13 32 |
|
|
|
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F11814g 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RDH54 30 33 |
|
||
| RAD54 31 |
|
OneToMany | |||
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AGL212W 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | rdh54 30 |
|
- Species where no ortholog for RAD54B was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for RAD54B Gene
- ENSEMBL:
- Gene Tree for RAD54B (if available)
- TreeFam:
- Gene Tree for RAD54B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for RAD54B: view image
Paralogs for RAD54B Gene
Paralogs for RAD54B Gene
- RAD54L 5
- CHD3 5
- CHD5 5
- ATRX 5
- CHD4 5
- CHD2 5
- CHD8 5
- ERCC6 5
- ENSG00000285238 5
- ENSG00000282034 5
- SRCAP 5
- SMARCA4 5
- SMARCA2 5
- CHD1 5
- CHD7 5
- EP400 5
- CHD9 5
- ERCC6L2 5
- BTAF1 5
- ERCC6L 5
- CHD6 5
- SMARCAD1 5
- RAD54L2 5
- CHD1L 5
- INO80 5
- SMARCA1 5
- TTF2 5
- SMARCA5 5
- HELLS 5
- HLTF 5
- ZRANB3 5
- SHPRH 5
- SMARCAL1 5
- ENSG00000279765 5
(2) SIMAP similar genes for RAD54B Gene using alignment to 4 proteins:
- RA54B_HUMAN
- E5RHN9_HUMAN
- E5RI14_HUMAN
- E5RJF7_HUMAN
Variants for RAD54B Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for RAD54B Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 722063 | Likely Benign: not provided | 94,378,363(-) | T/C | MISSENSE_VARIANT | |
| 722601 | Likely Benign: not provided | 94,372,169(-) | AC/A | STOP_LOST,FRAMESHIFT_VARIANT | |
| 728955 | Benign: not provided | 94,407,566(-) | C/T | SYNONYMOUS_VARIANT | |
| 774245 | Likely Benign: not provided | 94,372,264(-) | T/C | MISSENSE_VARIANT | |
| 784135 | Benign: not provided | 94,400,394(-) | C/T | SYNONYMOUS_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2104e212 | CNV | loss | 25503493 |
| dgv2105e212 | CNV | loss | 25503493 |
| esv3572904 | CNV | loss | 25503493 |
| esv3572905 | CNV | loss | 25503493 |
| esv3572908 | CNV | loss | 25503493 |
| esv3618077 | CNV | loss | 21293372 |
| nsv1031480 | CNV | gain | 25217958 |
| nsv611749 | CNV | loss | 21841781 |
| nsv6313 | CNV | insertion | 18451855 |
| nsv831401 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
68.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.05;
50.50% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for RAD54B Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for RAD54B Gene
Disorders for RAD54B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| lymphoma, non-hodgkin, familial |
|
|
| colorectal cancer |
|
|
| lymphoma |
|
|
Search RAD54B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for RAD54B
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for RAD54B Gene
Publications for RAD54B Gene
- A novel human rad54 homologue, Rad54B, associates with Rad51. (PMID: 10851248) Tanaka K … Miyagawa K (The Journal of biological chemistry 2000) 2 3 4 23
- Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer. (PMID: 10362364) Hiramoto T … Kamiya K (Oncogene 1999) 2 3 4 23
- Human Rad54B is a double-stranded DNA-dependent ATPase and has biochemical properties different from its structural homolog in yeast, Tid1/Rdh54. (PMID: 11884632) Tanaka K … Miyagawa K (Nucleic acids research 2002) 3 4 23
- Variation within DNA repair pathway genes and risk of multiple sclerosis. (PMID: 20522537) Briggs FB … International Multiple Sclerosis Genetics Consortium (American journal of epidemiology 2010) 3 41
- Gamma-radiation sensitivity and polymorphisms in RAD51L1 modulate glioma risk. (PMID: 20610542) Liu Y … Bondy ML (Carcinogenesis 2010) 3 41
ExternalLinks
Products for RAD54B Gene
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- OriGene qPCR primer pairs for RAD54B
- OriGene qPCR primer pairs and template standards for RAD54B
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- High-throughput Antibody Production Service
- Protein Production Service
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- Novus Biologicals proteins and lysates for RAD54B
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- Find your target
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- Invitrogen Antibodies for RAD54B (AFLGC-RAD54B)
- VectorBuilder Custom and pre-made DNA vectors for RAD54B (ie. gene expression, shRNA knockdown, CRISPR)
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- VectorBuilder Virus packaging for RAD54B CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for RAD54B
- Addgene plasmids for RAD54B
- antibodies-online: Show 11 available RAD54B Antibodies ranked by validation data
- Compare Top RAD54B Antibodies
- antibodies-online: Search results for available RAD54B related products ranked by validation data
- antibodies-online: Show 4 available RAD54B Proteins ranked by validation data
- Compare Top RAD54B Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for RAD54B
- Search Santa Cruz Biotechnology (SCBT) for RAD54B siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for RAD54B
- Horizon Cell Lines for RAD54B
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for RAD54B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for RAD54B
- Search GeneCopoeia for miRNA 3'UTR Target clone products for RAD54B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for RAD54B
- Boster Bio Antibodies for RAD54B
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for RAD54B
Sources for RAD54B Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB