Aliases for RABEP2 Gene
External Ids for RABEP2 Gene
Previous GeneCards Identifiers for RABEP2 Gene
GeneCards Summary for RABEP2 Gene
RABEP2 (Rabaptin, RAB GTPase Binding Effector Protein 2) is a Protein Coding gene. Diseases associated with RABEP2 include Brody Myopathy and Koolen-De Vries Syndrome. Gene Ontology (GO) annotations related to this gene include GTPase activator activity and growth factor activity. An important paralog of this gene is RABEP1.
UniProtKB/Swiss-Prot Summary for RABEP2 Gene
Plays a role in membrane trafficking and in homotypic early endosome fusion (PubMed:9524116). Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100). By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062).