Aliases for RAB40B Gene
External Ids for RAB40B Gene
Previous GeneCards Identifiers for RAB40B Gene
The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008]
GeneCards Summary for RAB40B Gene
RAB40B (RAB40B, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB40B include Epilepsy, Familial Temporal Lobe, 4. Among its related pathways are Metabolism of proteins and RAB geranylgeranylation. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB40AL.
UniProtKB/Swiss-Prot Summary for RAB40B Gene
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.