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RAB3D (RAB3D, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB3D include Esophageal Varix and Scleral Staphyloma. Among its related pathways are Metabolism of proteins and Autophagy Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase binding. An important paralog of this gene is RAB3A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0003924 | GTPase activity | TAS | -- |
GO:0005525 | GTP binding | IEA | -- |
GO:0030742 | GTP-dependent protein binding | IEA | -- |
GO:0031489 | myosin V binding | IPI | 24006491 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005768 | endosome | IBA | 21873635 |
GO:0005881 | cytoplasmic microtubule | IDA | 21262767 |
GO:0005886 | plasma membrane | TAS | -- |
GO:0008021 | synaptic vesicle | IBA | 21873635 |
GO:0012505 | endomembrane system | IBA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Innate Immune System |
.61
|
|
2 | Metabolism of proteins | ||
3 | Pancreatic secretion | ||
4 | Autophagy Pathway | ||
5 | Sertoli-Sertoli Cell Junction Dynamics |
Epithelial Tight Junctions
.36
|
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006886 | intracellular protein transport | IBA | -- |
GO:0006887 | exocytosis | IEA | -- |
GO:0006904 | vesicle docking involved in exocytosis | IBA | 21873635 |
GO:0009306 | protein secretion | IBA | 21873635 |
GO:0015031 | protein transport | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RAB3D 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RAB3D 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RAB3D 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | RAB3D 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Rab3d 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Rab3d 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | RAB3D 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RAB3D 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | rab3d 30 |
|
||
Str.4787 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | rab3db 31 |
|
OneToMany | |
rab3da 30 31 |
|
OneToMany | |||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4063 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | Rab3 31 32 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | rab-3 31 32 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
Disorder | Aliases | PubMed IDs |
---|---|---|
esophageal varix |
|
|
scleral staphyloma |
|
|
meckel diverticulum |
|
|
shoulder impingement syndrome |
|
|
vein disease |
|
|