Aliases for RAB39A Gene
External Ids for RAB39A Gene
Previous HGNC Symbols for RAB39A Gene
Previous GeneCards Identifiers for RAB39A Gene
GeneCards Summary for RAB39A Gene
RAB39A (RAB39A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Vesicle-mediated transport and RAB GEFs exchange GTP for GDP on RABs. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB39B.
UniProtKB/Swiss-Prot Summary for RAB39A Gene
Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in vesicular trafficking. Plays a role in the fusion of phagosomes with lysosomes. Negatively regulates LPS-induced autophagosome formation in macrophages possibly by implicating PI3K (PubMed:24349490). May be involved in multiple neurite formation (By similarity).