Aliases for RAB38 Gene
External Ids for RAB38 Gene
Previous GeneCards Identifiers for RAB38 Gene
GeneCards Summary for RAB38 Gene
RAB38 (RAB38, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB38 include Oculocutaneous Albinism and Hermansky-Pudlak Syndrome. Among its related pathways are Metabolism of proteins and RAB GEFs exchange GTP for GDP on RABs. Gene Ontology (GO) annotations related to this gene include GTP binding. An important paralog of this gene is RAB32.
UniProtKB/Swiss-Prot Summary for RAB38 Gene
May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).