Aliases for RAB30 Gene
External Ids for RAB30 Gene
Previous GeneCards Identifiers for RAB30 Gene
GeneCards Summary for RAB30 Gene
RAB30 (RAB30, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB30 include B-Lymphoblastic Leukemia/Lymphoma With Etv6-Runx1. Among its related pathways are Vesicle-mediated transport and Sertoli-Sertoli Cell Junction Dynamics. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB43.
UniProtKB/Swiss-Prot Summary for RAB30 Gene
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). Required for maintaining the structural integrity of the Golgi apparatus, possibly by mediating interactions with cytoplasmic scaffolding proteins.