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RAB29 (RAB29, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB29 include Kufor-Rakeb Syndrome and Frontotemporal Dementia. Among its related pathways are Metabolism of proteins and RAB geranylgeranylation. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RAB38.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000166 | nucleotide binding | IEA | -- |
GO:0003924 | GTPase activity | TAS,IBA | 21873635 |
GO:0005515 | protein binding | IPI | 24510904 |
GO:0005525 | GTP binding | IDA | 24510904 |
GO:0017137 | Rab GTPase binding | IDA | 26021297 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IEA,IDA | 24788816 |
GO:0005739 | mitochondrion | IDA | 25767741 |
GO:0005769 | early endosome | IDA | 26021297 |
GO:0005773 | vacuole | IEA | -- |
GO:0005794 | Golgi apparatus | IDA | 22042847 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Metabolism of proteins | ||
2 | RAB geranylgeranylation |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001921 | positive regulation of receptor recycling | IMP | 26021297 |
GO:0006886 | intracellular protein transport | IBA | 21873635 |
GO:0006888 | NOT ER to Golgi vesicle-mediated transport | IMP | 24788816 |
GO:0007005 | mitochondrion organization | IMP | 25767741 |
GO:0007030 | Golgi organization | IMP | 24510904 |
ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | · | 1g | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | · | 4d | · | 4e | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP8: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
SP9: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP10: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP11: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
SP12: | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
SP13: | - | ||||||||||||||||||||||||||||||||||||||||||||||||
SP14: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | RAB7L1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | RAB7L1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | RAB7L1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Rab7l1 30 31 |
|
OneToOne | |
Rab29 17 |
|
||||
Rat (Rattus norvegicus) |
Mammalia | Rab7l1 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | RAB7L1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | RAB7L1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | RAB7L1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | RAB7L1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100135159 30 |
|
||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.32195 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | si:ch73-173m3.3 31 |
|
ManyToMany |
Disorder | Aliases | PubMed IDs |
---|---|---|
kufor-rakeb syndrome |
|
|
frontotemporal dementia |
|
|
parkinson disease, late-onset |
|
|