Aliases for RAB26 Gene
External Ids for RAB26 Gene
Previous GeneCards Identifiers for RAB26 Gene
Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010]
GeneCards Summary for RAB26 Gene
RAB26 (RAB26, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB26 include Warburg Micro Syndrome. Among its related pathways are Metabolism of proteins and Autophagy Pathway. Gene Ontology (GO) annotations related to this gene include GTP binding and GMP binding. An important paralog of this gene is RAB37.
UniProtKB/Swiss-Prot Summary for RAB26 Gene
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland.