Aliases for RAB11FIP1 Gene
External Ids for RAB11FIP1 Gene
Previous GeneCards Identifiers for RAB11FIP1 Gene
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
GeneCards Summary for RAB11FIP1 Gene
RAB11FIP1 (RAB11 Family Interacting Protein 1) is a Protein Coding gene. Diseases associated with RAB11FIP1 include Griscelli Syndrome. Among its related pathways are Endocytosis and wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF). Gene Ontology (GO) annotations related to this gene include Rab GTPase binding. An important paralog of this gene is RAB11FIP5.
UniProtKB/Swiss-Prot Summary for RAB11FIP1 Gene
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in phagocytosis.