This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this ge... See more...

Aliases for QSOX1 Gene

Aliases for QSOX1 Gene

  • Quiescin Sulfhydryl Oxidase 1 2 3 5
  • Quiescin Q6 Sulfhydryl Oxidase 1 2 3
  • Sulfhydryl Oxidase 1 3 4
  • Thiol Oxidase 1 2 3
  • Quiescin Q6 2 4
  • EC 1.8.3.2 4 51
  • QSCN6 3 4
  • Testis Tissue Sperm-Binding Protein Li 62n 3
  • QSOX1 5
  • HQSOX 4
  • Q6 3

External Ids for QSOX1 Gene

Previous HGNC Symbols for QSOX1 Gene

  • QSCN6

Previous GeneCards Identifiers for QSOX1 Gene

  • GC01P178391
  • GC01P180123
  • GC01P151355

Summaries for QSOX1 Gene

Entrez Gene Summary for QSOX1 Gene

  • This gene encodes a protein that contains domains of thioredoxin and ERV1, members of two long-standing gene families. The gene expression is induced as fibroblasts begin to exit the proliferative cycle and enter quiescence, suggesting that this gene plays an important role in growth regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for QSOX1 Gene

QSOX1 (Quiescin Sulfhydryl Oxidase 1) is a Protein Coding gene. Diseases associated with QSOX1 include Breast Cancer. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include protein disulfide isomerase activity and flavin-linked sulfhydryl oxidase activity. An important paralog of this gene is QSOX2.

UniProtKB/Swiss-Prot Summary for QSOX1 Gene

  • Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:30367560, PubMed:23867277). Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:17331072, PubMed:30367560, PubMed:22801504, PubMed:23867277). In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:23704371, PubMed:30367560, PubMed:23867277).

Gene Wiki entry for QSOX1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for QSOX1 Gene

Genomics for QSOX1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for QSOX1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J180150 Promoter/Enhancer 2.5 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 649.7 +0.0 14 8.8 SP1 CREB1 GATAD2A ATF7 PRDM10 REST SOX13 IKZF1 ZNF692 POLR2A QSOX1 LOC105371636 lnc-ACBD6-3 LHX4-AS1 ENSG00000261831 AXDND1 ENSG00000260360 TOR1AIP1 CEP350 MN308835
GH01J180165 Enhancer 1.1 ENCODE dbSUPER 43.8 +13.5 13476 6 HNRNPL CREB1 CTCF PRDM10 ZNF692 ZHX2 JUND ZIC2 PKNOX1 PATZ1 piR-34309 QSOX1 piR-54514 LHX4
GH01J180130 Enhancer 1.2 Ensembl ENCODE dbSUPER 21.5 -25.5 -25532 8.6 GATAD2A SOX13 FOXA1 MTA2 PKNOX1 RXRB SP1 CEBPA CEBPB ZNF316 QSOX1 ENSG00000261831 LHX4 ENSG00000260360 lnc-CEP350-1 ENSG00000261817 lnc-ACBD6-3 CEP350
GH01J180173 Enhancer 0.7 Ensembl ENCODE dbSUPER 27.2 +19.2 19247 1.3 POLR2A SMARCA4 QSOX1 TOR1AIP2 TOR1AIP1 piR-54514 piR-34309 LHX4
GH01J180252 Enhancer 1.1 Ensembl ENCODE 16 +99.0 98968 3.2 HNRNPL GATAD2A CTCF FOXA1 MTA2 ZNF143 ZIC2 ZSCAN4 ZNF24 RXRB QSOX1 LHX4 RF00017-414 ACBD6
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around QSOX1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for QSOX1

Top Transcription factor binding sites by QIAGEN in the QSOX1 gene promoter:
  • AML1a
  • Cart-1
  • IRF-1
  • IRF-2
  • Pax-4a
  • POU2F1
  • POU2F1a
  • Spz1

Genomic Locations for QSOX1 Gene

Genomic Locations for QSOX1 Gene
chr1:180,154,833-180,204,030
(GRCh38/hg38)
Size:
49,198 bases
Orientation:
Plus strand
chr1:180,123,968-180,173,165
(GRCh37/hg19)
Size:
49,198 bases
Orientation:
Plus strand

Genomic View for QSOX1 Gene

Genes around QSOX1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
QSOX1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for QSOX1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for QSOX1 Gene

Proteins for QSOX1 Gene

  • Protein details for QSOX1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O00391-QSOX1_HUMAN
    Recommended name:
    Sulfhydryl oxidase 1
    Protein Accession:
    O00391
    Secondary Accessions:
    • Q59G29
    • Q5T2X0
    • Q8TDL6
    • Q8WVP4

    Protein attributes for QSOX1 Gene

    Size:
    747 amino acids
    Molecular mass:
    82578 Da
    Cofactor:
    Name=FAD; Xref=ChEBI:CHEBI:57692;
    Quaternary structure:
    • Monomer.
    SequenceCaution:
    • Sequence=BAD92517.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
    Miscellaneous:
    • 'Quiescin Q6' means that it was the sixth clone to be found at a higher level of expression in quiescent fibroblasts.

    Three dimensional structures from OCA and Proteopedia for QSOX1 Gene

    Alternative splice isoforms for QSOX1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for QSOX1 Gene

Selected DME Specific Peptides for QSOX1 Gene

O00391:
  • EDPQFPK
  • SWCGHCI
  • LFHFLTVQA
  • FPKVQWP
  • HFRGFPCSLW
  • ADRSKIYMADLESALHYILR

Post-translational modifications for QSOX1 Gene

  • N-glycosylated (PubMed:17331072, PubMed:29757379). O-glycosylated on Thr and Ser residues (PubMed:29757379).
  • Glycosylation at Asn130, Asn243, Thr276, Thr277, Thr281, Thr282, Thr289, Ser493, Ser549, Asn575, Ser576, Thr577, Ser588, Thr590, Asn591, Thr592, Thr593, Ser604, Ser643, Thr647, and Ser655
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • QSOX1_HUMAN (1774)

Other Protein References for QSOX1 Gene

Domains & Families for QSOX1 Gene

Gene Families for QSOX1 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Predicted secreted proteins

Protein Domains for QSOX1 Gene

Suggested Antigen Peptide Sequences for QSOX1 Gene

GenScript: Design optimal peptide antigens:
  • Bone-derived growth factor (Q13876_HUMAN)
  • Quiescin Q6 sulfhydryl oxidase 1 (Q5T2X6_HUMAN)
  • Quiescin Q6 (QSOX1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

O00391

UniProtKB/Swiss-Prot:

QSOX1_HUMAN :
  • Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
Family:
  • Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
genes like me logo Genes that share domains with QSOX1: view

Function for QSOX1 Gene

Molecular function for QSOX1 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:17331072, PubMed:18393449, PubMed:23704371, PubMed:30367560, PubMed:23867277). Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:17331072, PubMed:30367560, PubMed:22801504, PubMed:23867277). In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:23704371, PubMed:30367560, PubMed:23867277).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=O2 + 2 R'C(R)SH = H2O2 + R'C(R)S-S(R)CR'; Xref=Rhea:RHEA:17357, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:16520, ChEBI:CHEBI:17412; EC=1.8.3.2; Evidence={ECO:0000269|PubMed:18393449, ECO:0000269|PubMed:22801504, ECO:0000269|PubMed:23704371, ECO:0000269|PubMed:23867277, ECO:0000269|PubMed:26819240, ECO:0000269|PubMed:29757379, ECO:0000269|PubMed:30367560};.
UniProtKB/Swiss-Prot Induction:
Induced in quiescent cells just as fibroblasts begin to leave the proliferative cycle and enter quiescence.

Enzyme Numbers (IUBMB) for QSOX1 Gene

Phenotypes From GWAS Catalog for QSOX1 Gene

Gene Ontology (GO) - Molecular Function for QSOX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003756 protein disulfide isomerase activity IBA,IDA 17331072
GO:0016491 oxidoreductase activity IEA --
GO:0016971 flavin-linked sulfhydryl oxidase activity IBA,IDA 17331072
GO:0016972 thiol oxidase activity IEA --
GO:0071949 FAD binding IDA 20211621
genes like me logo Genes that share ontologies with QSOX1: view
genes like me logo Genes that share phenotypes with QSOX1: view

Animal Model Products

CRISPR Products

miRNA for QSOX1 Gene

miRTarBase miRNAs that target QSOX1

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for QSOX1

Clone Products

  • Addgene plasmids for QSOX1

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for QSOX1 Gene

Localization for QSOX1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for QSOX1 Gene

[Isoform 1]: Golgi apparatus membrane. Single-pass membrane protein. Secreted. Note=A small proportion is secreted, probably via a proteolytic cleavage that removes the membrane anchor. {ECO:0000305 PubMed:29757379}.
[Isoform 2]: Secreted. Note=Found in the extracellular medium of quiescent cells but is not found in proliferating cells. {ECO:0000269 PubMed:10708601}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for QSOX1 gene
Compartment Confidence
extracellular 5
golgi apparatus 5
endoplasmic reticulum 4
plasma membrane 1
cytoskeleton 1
mitochondrion 1
nucleus 1
endosome 1
cytosol 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Golgi apparatus (3)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for QSOX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA,IDA 29757379
GO:0005576 extracellular region TAS --
GO:0005615 extracellular space IBA,IDA 10708601
GO:0005623 cell IEA --
GO:0005788 endoplasmic reticulum lumen TAS --
genes like me logo Genes that share ontologies with QSOX1: view

Pathways & Interactions for QSOX1 Gene

genes like me logo Genes that share pathways with QSOX1: view

Gene Ontology (GO) - Biological Process for QSOX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002576 platelet degranulation TAS --
GO:0006457 protein folding IBA 21873635
GO:0016242 negative regulation of macroautophagy IMP 24475161
GO:0043312 neutrophil degranulation TAS --
GO:0043687 post-translational protein modification TAS --
genes like me logo Genes that share ontologies with QSOX1: view

No data available for SIGNOR curated interactions for QSOX1 Gene

Drugs & Compounds for QSOX1 Gene

(4) Drugs for QSOX1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
FAD Approved Pharma 0
Hydrogen peroxide Approved, Vet_approved Pharma 115
Oxygen Approved, Vet_approved Pharma 0
Water Approved Pharma 0
genes like me logo Genes that share compounds with QSOX1: view

Transcripts for QSOX1 Gene

mRNA/cDNA for QSOX1 Gene

2 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for QSOX1

Clone Products

  • Addgene plasmids for QSOX1

Alternative Splicing Database (ASD) splice patterns (SP) for QSOX1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12a · 12b ^ 13a · 13b · 13c ^ 14a · 14b
SP1: - - -
SP2: -
SP3: -
SP4: - - - - - - -
SP5: - -
SP6: - - -
SP7: -
SP8:
SP9: -

Relevant External Links for QSOX1 Gene

GeneLoc Exon Structure for
QSOX1

Expression for QSOX1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for QSOX1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for QSOX1 Gene

This gene is overexpressed in Amniocyte (19.2), Milk (10.4), and Serum (7.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for QSOX1 Gene



Protein tissue co-expression partners for QSOX1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for QSOX1

SOURCE GeneReport for Unigene cluster for QSOX1 Gene:

Hs.744925

mRNA Expression by UniProt/SwissProt for QSOX1 Gene:

O00391-QSOX1_HUMAN
Tissue specificity: Expressed in heart, placenta, lung, liver, skeletal muscle, pancreas and very weakly in brain and kidney.

Evidence on tissue expression from TISSUES for QSOX1 Gene

  • Lung(5)
  • Nervous system(4.9)
  • Kidney(4.8)
  • Bone marrow(4.4)
  • Stomach(3.8)
  • Intestine(3.5)
  • Skin(3.5)
  • Pancreas(2.7)
  • Heart(2.4)
  • Muscle(2.3)
  • Liver(2)
genes like me logo Genes that share expression patterns with QSOX1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for QSOX1 Gene

Orthologs for QSOX1 Gene

This gene was present in the common ancestor of animals.

Orthologs for QSOX1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia QSOX1 30 31
  • 99.28 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia QSOX1 30 31
  • 85.38 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Qsox1 30
  • 79.18 (n)
Mouse
(Mus musculus)
Mammalia Qsox1 30 17 31
  • 78.59 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia QSOX1 31
  • 74 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia QSOX1 31
  • 54 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia QSOX1 31
  • 53 (a)
OneToOne
Chicken
(Gallus gallus)
Aves QSOX1 30 31
  • 62.31 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia QSOX1 31
  • 42 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia qsox1 30
  • 51.78 (n)
Zebrafish
(Danio rerio)
Actinopterygii qsox1 30 31
  • 53.4 (n)
OneToOne
sbcb840 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP007491 30
  • 47.46 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta CG4670 30 31
  • 46.57 (n)
ManyToMany
CG17843 31
  • 29 (a)
ManyToMany
CG31413 31
  • 25 (a)
ManyToMany
CG6690 31
  • 25 (a)
ManyToMany
Worm
(Caenorhabditis elegans)
Secernentea T10H10.2 30 31
  • 43.01 (n)
ManyToMany
F47B7.2 31
  • 22 (a)
ManyToMany
F35G2.1 31
  • 22 (a)
ManyToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 24 (a)
OneToMany
Species where no ortholog for QSOX1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for QSOX1 Gene

ENSEMBL:
Gene Tree for QSOX1 (if available)
TreeFam:
Gene Tree for QSOX1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for QSOX1: view image

Paralogs for QSOX1 Gene

Paralogs for QSOX1 Gene

(4) SIMAP similar genes for QSOX1 Gene using alignment to 3 proteins:

  • QSOX1_HUMAN
  • A8MXT8_HUMAN
  • H0Y5Z8_HUMAN
genes like me logo Genes that share paralogs with QSOX1: view

Variants for QSOX1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for QSOX1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
709336 Benign: not provided 180,196,252(+) C/T INTRON_VARIANT
720745 Benign: not provided 180,196,812(+) C/A SYNONYMOUS_VARIANT,INTRON_VARIANT
746984 Likely Benign: not provided 180,190,513(+) G/A SYNONYMOUS_VARIANT
747248 Likely Benign: not provided 180,178,787(+) C/T INTRON_VARIANT
773117 Benign: not provided 180,186,188(+) C/A INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for QSOX1 Gene

Structural Variations from Database of Genomic Variants (DGV) for QSOX1 Gene

Variant ID Type Subtype PubMed ID
dgv474n100 CNV gain 25217958
dgv475n100 CNV gain 25217958
dgv476n100 CNV gain 25217958
nsv1001565 CNV loss 25217958
nsv1119737 CNV deletion 24896259
nsv466239 CNV gain 19166990
nsv472946 CNV novel sequence insertion 20440878
nsv522045 CNV loss 19592680
nsv528041 CNV loss 19592680
nsv548345 CNV gain 21841781
nsv832004 CNV gain 17160897
nsv952285 CNV deletion 24416366

Variation tolerance for QSOX1 Gene

Residual Variation Intolerance Score: 36% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.57; 77.96% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for QSOX1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
QSOX1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for QSOX1 Gene

Disorders for QSOX1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for QSOX1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
breast cancer
  • breast lobular carcinoma
- elite association - COSMIC cancer census association via MalaCards
Search QSOX1 in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with QSOX1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for QSOX1 Gene

Publications for QSOX1 Gene

  1. The quiescin Q6 gene (QSCN6) is a fusion of two ancient gene families: thioredoxin and ERV1. (PMID: 9878249) Coppock DL … Gilleran S (Genomics 1998) 2 3 4 23
  2. Sulfhydryl oxidases: emerging catalysts of protein disulfide bond formation in eukaryotes. (PMID: 12176051) Thorpe C … Coppock DL (Archives of biochemistry and biophysics 2002) 2 3 4
  3. Regulation of the quiescence-induced genes: quiescin Q6, decorin, and ribosomal protein S29. (PMID: 10708601) Coppock D … Cina-Poppe DA (Biochemical and biophysical research communications 2000) 3 4 23
  4. Preferential gene expression in quiescent human lung fibroblasts. (PMID: 8396966) Coppock DL … Gilleran S (Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993) 2 3 23
  5. cis-Proline mutants of quiescin sulfhydryl oxidase 1 with altered redox properties undermine extracellular matrix integrity and cell adhesion in fibroblast cultures. (PMID: 30367560) Javitt G … Fass D (Protein science : a publication of the Protein Society 2019) 3 4

Products for QSOX1 Gene

Sources for QSOX1 Gene