Aliases for QRFP Gene
External Ids for QRFP Gene
Previous GeneCards Identifiers for QRFP Gene
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015]
GeneCards Summary for QRFP Gene
QRFP (Pyroglutamylated RFamide Peptide) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include neuropeptide hormone activity and orexigenic neuropeptide QRFP receptor binding.
UniProtKB/Swiss-Prot Summary for QRFP Gene
Stimulates feeding behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland (By similarity).