Aliases for PXN-AS1 Gene

Subcategory (RNA class) for PXN-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for PXN-AS1 Gene

  • PXN Antisense RNA 1 2 3 5
  • PXN Antisense RNA 1 (Non-Protein Coding) 2 3
  • PXN-AS1 2 168
  • HSALNG0094500 167
  • NONHSAG012505 92
  • EyeLinc4 3

External Ids for PXN-AS1 Gene

Previous GeneCards Identifiers for PXN-AS1 Gene

  • GC12P120641

Summaries for PXN-AS1 Gene

GeneCards Summary for PXN-AS1 Gene

PXN-AS1 (PXN Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class.

Additional gene information for PXN-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PXN-AS1 Gene

Genomics for PXN-AS1 Gene

GeneHancer (GH) Regulatory Elements for PXN-AS1 Gene

Promoters and enhancers for PXN-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J120193 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas 510.9 +0.6 587 4.6 HNRNPK ZBTB40 ZNF217 EP300 SIN3A MYC POLR2G GTF2E2 PHF8 ZFX GCN1 PXN-AS1 lnc-GCN1-1 RAB35 RPL31P52 PXN RPLP0 PRKAB1 SIRT4 RF00017-1304
GH12J120115 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 12 -76.0 -76018 7.8 FOXK2 ZBTB40 EP300 SIN3A NRF1 USF1 POLR2G SP1 NCOR1 PHF8 RAB35 ENSG00000277283 GCN1 RPLP0 PXN PXN-AS1 COQ5 lnc-RAB35-1 RF00017-1304
GH12J120223 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.8 +36.6 36589 15.9 EP300 ZNF217 CTCF TCF12 MYC POLR2G USF1 NCOR1 JUND TEAD4 PXN SIRT4 RPLP0 RNU4-1 RNU4-2 PXN-AS1 PLA2G1B GCN1 RAB35 MSI1
GH12J120430 Enhancer 1.1 Ensembl ENCODE 10.3 +235.8 235837 1.1 CTCF MYC SP1 REST KLF7 USF2 RAD21 CTBP1 TRIM22 SMC3 RPL31P52 GATC RAB35 MSI1 RPS27P25 PLA2G1B SRSF9 DYNLL1 RNU6-1088P GCN1
GH12J120125 Enhancer 0.8 ENCODE dbSUPER 11.6 -68.1 -68062 2.2 POLR2G RFX1 CTBP1 POLR2A RBM22 SPI1 FOS SUPT5H EBF1 MAX PXN-AS1 RPLP0 GCN1 PXN RAB35 lnc-RAB35-1 RF00017-1304
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PXN-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PXN-AS1 Gene

Genomic Locations for PXN-AS1 Gene
chr12:120,194,917-120,213,231
(GRCh38/hg38)
Size:
18,315 bases
Orientation:
Plus strand
chr12:120,639,094-120,650,941
(GRCh37/hg19)
Size:
11,848 bases
Orientation:
Plus strand

Genomic View for PXN-AS1 Gene

Genes around PXN-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PXN-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PXN-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PXN-AS1 Gene

Proteins for PXN-AS1 Gene

Post-translational modifications for PXN-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PXN-AS1 Gene

Domains & Families for PXN-AS1 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for PXN-AS1 Gene

Function for PXN-AS1 Gene

Phenotypes From GWAS Catalog for PXN-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PXN-AS1 Gene

Localization for PXN-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PXN-AS1 Gene

Pathways & Interactions for PXN-AS1 Gene

PathCards logo

SuperPathways for PXN-AS1 Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for PXN-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for PXN-AS1 Gene

Drugs & Compounds for PXN-AS1 Gene

No Compound Related Data Available

Transcripts for PXN-AS1 Gene

mRNA/cDNA for PXN-AS1 Gene

23 RNACentral transcripts :
1 REFSEQ mRNAs :
2 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
8 NONCODE transcripts :
12 LncBook transcripts :
10 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for PXN-AS1 Gene

No ASD Table

Relevant External Links for PXN-AS1 Gene

GeneLoc Exon Structure for
PXN-AS1

Expression for PXN-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PXN-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for PXN-AS1 Gene

This gene is overexpressed in Whole Blood (x8.3).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PXN-AS1

SOURCE GeneReport for Unigene cluster for PXN-AS1 Gene:

Hs.569205
genes like me logo Genes that share expression patterns with PXN-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PXN-AS1 Gene

Orthologs for PXN-AS1 Gene

Evolution for PXN-AS1 Gene

ENSEMBL:
Gene Tree for PXN-AS1 (if available)
TreeFam:
Gene Tree for PXN-AS1 (if available)

No data available for Orthologs for PXN-AS1 Gene

Paralogs for PXN-AS1 Gene

No data available for Paralogs for PXN-AS1 Gene

Variants for PXN-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PXN-AS1 Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
715656 Benign: not provided 120,212,569(+) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for PXN-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for PXN-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv519657 CNV loss 19592680
nsv560433 CNV loss 21841781
nsv832530 CNV loss 17160897

Additional Variant Information for PXN-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PXN-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PXN-AS1 Gene

Disorders for PXN-AS1 Gene

Additional Disease Information for PXN-AS1

No disorders were found for PXN-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PXN-AS1 Gene

Publications for PXN-AS1 Gene

  1. Long noncoding RNA PXN-AS1-L promotes the malignancy of nasopharyngeal carcinoma cells via upregulation of SAPCD2. (PMID: 31173488) Jia X … Liu H (Cancer medicine 2019) 2 3 54
  2. RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination. (PMID: 29117863) Choudhury NR … Michlewski G (BMC biology 2017) 3 54
  3. Long non-coding RNA PXN-AS1 suppresses pancreatic cancer progression by acting as a competing endogenous RNA of miR-3064 to upregulate PIP4K2B expression. (PMID: 31488171) Yan J … Zhou X (Journal of experimental & clinical cancer research : CR 2019) 3

Products for PXN-AS1 Gene

Sources for PXN-AS1 Gene