Aliases for PXK Gene
External Ids for PXK Gene
Previous GeneCards Identifiers for PXK Gene
This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
GeneCards Summary for PXK Gene
PXK (PX Domain Containing Serine/Threonine Kinase Like) is a Protein Coding gene. Diseases associated with PXK include Systemic Lupus Erythematosus. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and nucleotide binding.
UniProtKB/Swiss-Prot for PXK Gene
Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.