Aliases for PWP1 Gene
External Ids for PWP1 Gene
Previous GeneCards Identifiers for PWP1 Gene
The protein encoded by this gene contains several WD-40 repeats and is found mostly in the nucleus. The expression and localization of this protein are cell cycle dependent. Expression of this gene is upregulated in pancreatic adenocarcinoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]
GeneCards Summary for PWP1 Gene
PWP1 (PWP1 Homolog, Endonuclein) is a Protein Coding gene.
UniProtKB/Swiss-Prot for PWP1 Gene
Chromatin-associated factor that regulates transcription (PubMed:29065309). Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription (PubMed:29065309). Regulates the epigenetic status of rDNA (PubMed:29065309).