Aliases for PVALEF Gene

Aliases for PVALEF Gene

  • Parvalbumin Like EF-Hand Containing 2 3 5
  • Parvalbumin-Like EF-Hand-Containing Protein 3 4
  • AATK Antisense RNA 1 (Non-Protein Coding) 2 3
  • AATK Antisense RNA 1 2
  • AATK-AS1 3
  • PVALEF 5

External Ids for PVALEF Gene

Previous HGNC Symbols for PVALEF Gene

  • AATK-AS1

Summaries for PVALEF Gene

GeneCards Summary for PVALEF Gene

PVALEF (Parvalbumin Like EF-Hand Containing) is a Protein Coding gene.

Additional gene information for PVALEF Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PVALEF Gene

Genomics for PVALEF Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PVALEF Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PVALEF on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PVALEF

Genomic Locations for PVALEF Gene

Genomic Locations for PVALEF Gene
chr17:81,165,507-81,183,166
(GRCh38/hg38)
Size:
17,660 bases
Orientation:
Plus strand
chr17:79,139,307-79,156,964
(GRCh37/hg19)
Size:
17,658 bases
Orientation:
Plus strand

Genomic View for PVALEF Gene

Genes around PVALEF on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PVALEF Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PVALEF Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PVALEF Gene

Proteins for PVALEF Gene

  • Protein details for PVALEF Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A1B0GWK0-PVLEF_HUMAN
    Recommended name:
    Parvalbumin-like EF-hand-containing protein
    Protein Accession:
    A0A1B0GWK0

    Protein attributes for PVALEF Gene

    Size:
    134 amino acids
    Molecular mass:
    15275 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PVALEF Gene

Post-translational modifications for PVALEF Gene

No Post-translational modifications

Other Protein References for PVALEF Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PVALEF Gene

Domains & Families for PVALEF Gene

Gene Families for PVALEF Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for PVALEF Gene

Graphical View of Domain Structure for InterPro Entry

A0A1B0GWK0

UniProtKB/Swiss-Prot:

PVLEF_HUMAN :
  • Belongs to the parvalbumin family.
Family:
  • Belongs to the parvalbumin family.
genes like me logo Genes that share domains with PVALEF: view

No data available for Suggested Antigen Peptide Sequences for PVALEF Gene

Function for PVALEF Gene

Phenotypes From GWAS Catalog for PVALEF Gene

Gene Ontology (GO) - Molecular Function for PVALEF Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005509 calcium ion binding IEA --
GO:0046872 metal ion binding IEA --
GO:0048306 calcium-dependent protein binding IBA 21873635
GO:0051015 actin filament binding IBA 21873635
genes like me logo Genes that share ontologies with PVALEF: view

Phenotypes for PVALEF Gene

GenomeRNAi human phenotypes for PVALEF:
genes like me logo Genes that share phenotypes with PVALEF: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PVALEF

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PVALEF Gene

Localization for PVALEF Gene

Gene Ontology (GO) - Cellular Components for PVALEF Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005861 troponin complex IBA 21873635
genes like me logo Genes that share ontologies with PVALEF: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for PVALEF Gene

Pathways & Interactions for PVALEF Gene

PathCards logo

SuperPathways for PVALEF Gene

No Data Available

Interacting Proteins for PVALEF Gene

Gene Ontology (GO) - Biological Process for PVALEF Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003009 skeletal muscle contraction IBA 21873635
GO:0006937 regulation of muscle contraction IBA 21873635
genes like me logo Genes that share ontologies with PVALEF: view

No data available for Pathways by source and SIGNOR curated interactions for PVALEF Gene

Drugs & Compounds for PVALEF Gene

No Compound Related Data Available

Transcripts for PVALEF Gene

mRNA/cDNA for PVALEF Gene

2 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PVALEF

Alternative Splicing Database (ASD) splice patterns (SP) for PVALEF Gene

No ASD Table

Relevant External Links for PVALEF Gene

GeneLoc Exon Structure for
PVALEF

Expression for PVALEF Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PVALEF

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PVALEF Gene

Orthologs for PVALEF Gene

Evolution for PVALEF Gene

ENSEMBL:
Gene Tree for PVALEF (if available)
TreeFam:
Gene Tree for PVALEF (if available)

No data available for Orthologs for PVALEF Gene

Paralogs for PVALEF Gene

No data available for Paralogs for PVALEF Gene

Variants for PVALEF Gene

Additional dbSNP identifiers (rs#s) for PVALEF Gene

Structural Variations from Database of Genomic Variants (DGV) for PVALEF Gene

Variant ID Type Subtype PubMed ID
dgv3292n100 CNV gain 25217958
dgv46n68 CNV loss 17160897
esv26223 CNV gain+loss 19812545
esv2758707 CNV gain 17122850
esv3353282 CNV duplication 20981092
esv3554876 CNV deletion 23714750
nsv1057306 CNV loss 25217958
nsv1064123 CNV gain 25217958
nsv1065052 CNV gain 25217958
nsv1066947 CNV loss 25217958
nsv1127605 CNV deletion 24896259
nsv1143868 CNV deletion 24896259
nsv428351 CNV gain 18775914
nsv470619 CNV loss 18288195
nsv473977 CNV novel sequence insertion 20440878
nsv828128 CNV loss 20364138
nsv828133 CNV loss 20364138
nsv952389 CNV deletion 24416366

Additional Variant Information for PVALEF Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PVALEF

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for PVALEF Gene

Disorders for PVALEF Gene

Additional Disease Information for PVALEF

No disorders were found for PVALEF Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PVALEF Gene

Publications for PVALEF Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3
  2. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3

Products for PVALEF Gene

Sources for PVALEF Gene