This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq... See more...

Aliases for PUM2 Gene

Aliases for PUM2 Gene

  • Pumilio RNA Binding Family Member 2 2 3 5
  • PUMH2 2 3 4
  • Pumilio Homolog 2 3 4
  • Pumilio-2 3 4
  • KIAA0235 2 4
  • Pumilio Homolog 2 (Drosophila) 2
  • PUML2 3
  • PUM2 5

External Ids for PUM2 Gene

Previous GeneCards Identifiers for PUM2 Gene

  • GC02M020339
  • GC02M020516
  • GC02M020416
  • GC02M020432
  • GC02M020370
  • GC02M020311
  • GC02M020448
  • GC02M020205
  • GC02M020249
  • GC02M020253
  • GC02M020260

Summaries for PUM2 Gene

Entrez Gene Summary for PUM2 Gene

  • This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

GeneCards Summary for PUM2 Gene

PUM2 (Pumilio RNA Binding Family Member 2) is a Protein Coding gene. Among its related pathways are Spinocerebellar ataxia and Translational Control. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is PUM1.

UniProtKB/Swiss-Prot Summary for PUM2 Gene

  • Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE) (, PubMed:21397187). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation (PubMed:22955276). Also mediates deadenylation-independent repression by promoting accessibility of miRNAs (PubMed:18776931, PubMed:22345517). Acts as a post-transcriptional repressor of E2F3 mRNAs by binding to its 3'-UTR and facilitating miRNA regulation (PubMed:22345517). Plays a role in cytoplasmic sensing of viral infection (PubMed:25340845). Represses a program of genes necessary to maintain genomic stability such as key mitotic, DNA repair and DNA replication factors. Its ability to repress those target mRNAs is regulated by the lncRNA NORAD (non-coding RNA activated by DNA damage) which, due to its high abundance and multitude of PUMILIO binding sites, is able to sequester a significant fraction of PUM1 and PUM2 in the cytoplasm (PubMed:26724866). May regulate DCUN1D3 mRNA levels (PubMed:25349211). May support proliferation and self-renewal of stem cells. Binds specifically to miRNA MIR199A precursor, with PUM1, regulates miRNA MIR199A expression at a postranscriptional level (PubMed:28431233).

Gene Wiki entry for PUM2 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PUM2 Gene

Genomics for PUM2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PUM2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PUM2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PUM2

Top Transcription factor binding sites by QIAGEN in the PUM2 gene promoter:
  • CUTL1
  • FOXO4
  • Gfi-1
  • HNF-3beta
  • Pbx1a
  • POU2F1
  • POU2F1a
  • SRF
  • SRF (504 AA)
  • TBP

Genomic Locations for PUM2 Gene

Latest Assembly
chr2:20,248,691-20,352,253
(GRCh38/hg38)
Size:
103,563 bases
Orientation:
Minus strand

Previous Assembly
chr2:20,448,452-20,552,014
(GRCh37/hg19 by Entrez Gene)
Size:
103,563 bases
Orientation:
Minus strand

chr2:20,448,452-20,551,995
(GRCh37/hg19 by Ensembl)
Size:
103,544 bases
Orientation:
Minus strand

Genomic View for PUM2 Gene

Genes around PUM2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PUM2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PUM2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PUM2 Gene

Proteins for PUM2 Gene

  • Protein details for PUM2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8TB72-PUM2_HUMAN
    Recommended name:
    Pumilio homolog 2
    Protein Accession:
    Q8TB72
    Secondary Accessions:
    • B3KSL0
    • B4E2B6
    • D6W527
    • O00234
    • Q53TV7
    • Q8WY43
    • Q9HAN2

    Protein attributes for PUM2 Gene

    Size:
    1066 amino acids
    Molecular mass:
    114216 Da
    Quaternary structure:
    • Homodimer; homodimerizes in vitro. Interacts with DAZ, DAZL and NANOS1 via its pumilio repeats. Interacts with NANOS3 (By similarity). Interacts with SNAPIN. Recruits the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. Interacts with DDX20. In case of viral infection, interacts with DHX58 (PubMed:25340845). Interacts with TRIM71 (via NHL repeats) in an RNA-dependent manner (PubMed:23125361).

    Three dimensional structures from OCA and Proteopedia for PUM2 Gene

    Alternative splice isoforms for PUM2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PUM2 Gene

Post-translational modifications for PUM2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for PUM2 Gene

Domains & Families for PUM2 Gene

Gene Families for PUM2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for PUM2 Gene

Suggested Antigen Peptide Sequences for PUM2 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ53521, highly similar to Pumilio homolog 2 (B4E2B6_HUMAN)
  • Pumilio homolog 2 (Drosophila), isoform CRA_b (B7ZL34_HUMAN)
  • Pumilio homolog 2 (PUM2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q8TB72

UniProtKB/Swiss-Prot:

PUM2_HUMAN :
  • The pumilio repeats mediate the association with RNA by packing together to form a right-handed superhelix that approximates a half donut. RNA-binding occurs on the concave side of the surface (PubMed:21397187). PUM2 is composed of 8 pumilio repeats of 36 residues; each repeat binds a single nucleotide in its RNA target. Residues at positions 12 and 16 of the pumilio repeat bind each RNA base via hydrogen bonding or van der Waals contacts with the Watson-Crick edge, while the amino acid at position 13 makes a stacking interaction. The recognition of RNA by pumilio repeats is base specific: cysteine and glutamine at position 12 and 16, respectively, bind adenine; asparagine and glutamine bind uracil; and serine and glutamate bind guanine.
Domain:
  • The pumilio repeats mediate the association with RNA by packing together to form a right-handed superhelix that approximates a half donut. RNA-binding occurs on the concave side of the surface (PubMed:21397187). PUM2 is composed of 8 pumilio repeats of 36 residues; each repeat binds a single nucleotide in its RNA target. Residues at positions 12 and 16 of the pumilio repeat bind each RNA base via hydrogen bonding or van der Waals contacts with the Watson-Crick edge, while the amino acid at position 13 makes a stacking interaction. The recognition of RNA by pumilio repeats is base specific: cysteine and glutamine at position 12 and 16, respectively, bind adenine; asparagine and glutamine bind uracil; and serine and glutamate bind guanine.
genes like me logo Genes that share domains with PUM2: view

Function for PUM2 Gene

Molecular function for PUM2 Gene

UniProtKB/Swiss-Prot Function:
Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE) (, PubMed:21397187). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation (PubMed:22955276). Also mediates deadenylation-independent repression by promoting accessibility of miRNAs (PubMed:18776931, PubMed:22345517). Acts as a post-transcriptional repressor of E2F3 mRNAs by binding to its 3'-UTR and facilitating miRNA regulation (PubMed:22345517). Plays a role in cytoplasmic sensing of viral infection (PubMed:25340845). Represses a program of genes necessary to maintain genomic stability such as key mitotic, DNA repair and DNA replication factors. Its ability to repress those target mRNAs is regulated by the lncRNA NORAD (non-coding RNA activated by DNA damage) which, due to its high abundance and multitude of PUMILIO binding sites, is able to sequester a significant fraction of PUM1 and PUM2 in the cytoplasm (PubMed:26724866). May regulate DCUN1D3 mRNA levels (PubMed:25349211). May support proliferation and self-renewal of stem cells. Binds specifically to miRNA MIR199A precursor, with PUM1, regulates miRNA MIR199A expression at a postranscriptional level (PubMed:28431233).
UniProtKB/Swiss-Prot Induction:
Down-regulated in keratinocytes upon UVB irradiation.

Phenotypes From GWAS Catalog for PUM2 Gene

Gene Ontology (GO) - Molecular Function for PUM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IDA 26724866
GO:0003729 mRNA binding IBA 21873635
GO:0003730 mRNA 3'-UTR binding IDA 18776931
GO:0005515 protein binding IPI 12511597
GO:0035198 miRNA binding IDA 28431233
genes like me logo Genes that share ontologies with PUM2: view
genes like me logo Genes that share phenotypes with PUM2: view

Animal Models for PUM2 Gene

MGI Knock Outs for PUM2:
  • Pum2 Pum2<tm1b(KOMP)Wtsi>

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PUM2

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PUM2 Gene

Localization for PUM2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PUM2 Gene

Cytoplasm. Cytoplasmic granule. Cytoplasm, perinuclear region. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Colocalizes with NANOS3 in the stress granules. Colocalizes with NANOS1 and SNAPIN in the perinuclear region of germ cells. {ECO:0000269 PubMed:25340845}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PUM2 gene
Compartment Confidence
nucleus 5
cytosol 5
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for PUM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA 21873635
GO:0005829 cytosol IDA --
GO:0010494 cytoplasmic stress granule IEA,ISS --
GO:0031965 nuclear membrane IDA --
GO:0048471 perinuclear region of cytoplasm IEA,IDA 19168546
genes like me logo Genes that share ontologies with PUM2: view

Pathways & Interactions for PUM2 Gene

PathCards logo

SuperPathways for PUM2 Gene

genes like me logo Genes that share pathways with PUM2: view

Pathways by source for PUM2 Gene

1 KEGG pathway for PUM2 Gene
1 Cell Signaling Technology pathway for PUM2 Gene

Gene Ontology (GO) - Biological Process for PUM2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006417 regulation of translation IEA --
GO:0010608 posttranscriptional regulation of gene expression IEA,IMP 28431233
GO:0034063 stress granule assembly IEA --
GO:0035196 production of miRNAs involved in gene silencing by miRNA IMP 28431233
GO:0043488 regulation of mRNA stability IBA,IDA 26724866
genes like me logo Genes that share ontologies with PUM2: view

No data available for SIGNOR curated interactions for PUM2 Gene

Drugs & Compounds for PUM2 Gene

No Compound Related Data Available

Transcripts for PUM2 Gene

mRNA/cDNA for PUM2 Gene

15 REFSEQ mRNAs :
13 NCBI additional mRNA sequence :
9 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PUM2

Alternative Splicing Database (ASD) splice patterns (SP) for PUM2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17a · 17b ^ 18a · 18b ^ 19a ·
SP1: - - - -
SP2: -
SP3: - - -
SP4:
SP5: - - -
SP6: -
SP7:
SP8: - - -
SP9:

ExUns: 19b ^ 20a · 20b ^ 21 ^ 22 ^ 23 ^ 24 ^ 25a · 25b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:

Relevant External Links for PUM2 Gene

GeneLoc Exon Structure for
PUM2

Expression for PUM2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PUM2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for PUM2 Gene

This gene is overexpressed in Placenta (15.1), NK cells (9.2), and Tlymphocyte (9.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PUM2 Gene



Protein tissue co-expression partners for PUM2 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PUM2

SOURCE GeneReport for Unigene cluster for PUM2 Gene:

Hs.467824

mRNA Expression by UniProt/SwissProt for PUM2 Gene:

Q8TB72-PUM2_HUMAN
Tissue specificity: Expressed in male germ cells of adult testis (at protein level). Highly expressed in testis and ovary. Predominantly expressed in stem cells and germ cells. Expressed at lower level in brain, heart, kidney, liver, muscle, placenta, intestine and stomach Expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested.

Evidence on tissue expression from TISSUES for PUM2 Gene

  • Nervous system(4.8)
  • Liver(4.4)
  • Lung(4.4)
  • Skin(2.5)
  • Kidney(2.4)
  • Muscle(2.3)
  • Heart(2.1)
genes like me logo Genes that share expression patterns with PUM2: view

Primer products for research

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for PUM2 Gene

Orthologs for PUM2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for PUM2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia PUM2 29 30
  • 99.69 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia PUM2 29 30
  • 96.48 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia PUM2 29 30
  • 96.2 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 30
  • 96 (a)
OneToMany
-- 30
  • 94 (a)
OneToMany
-- 30
  • 73 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Pum2 29 16 30
  • 94.31 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Pum2 29
  • 93.93 (n)
Oppossum
(Monodelphis domestica)
Mammalia PUM2 30
  • 91 (a)
OneToOne
Chicken
(Gallus gallus)
Aves PUM2 29 30
  • 86.57 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia PUM2 30
  • 93 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia pum2 29
  • 76.94 (n)
Zebrafish
(Danio rerio)
Actinopterygii pum2 30
  • 68 (a)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta pum 30 31
  • 30 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea puf-9 31
  • 59 (a)
puf-8 31
  • 43 (a)
puf-3 30
  • 25 (a)
ManyToMany
puf-11 30
  • 22 (a)
ManyToMany
fbf-2 30
  • 21 (a)
ManyToMany
puf-7 30
  • 21 (a)
ManyToMany
fbf-1 30
  • 21 (a)
ManyToMany
puf-6 30
  • 20 (a)
ManyToMany
puf-5 30
  • 20 (a)
ManyToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PUF3 30 32
  • 29 (a)
OneToMany
Soybean
(Glycine max)
eudicotyledons Gma.2466 29
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.9347 30
  • 68 (a)
OneToMany
Species where no ortholog for PUM2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for PUM2 Gene

ENSEMBL:
Gene Tree for PUM2 (if available)
TreeFam:
Gene Tree for PUM2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for PUM2: view image
Alliance of Genome Resources:
Additional Orthologs for PUM2

Paralogs for PUM2 Gene

Paralogs for PUM2 Gene

(1) SIMAP similar genes for PUM2 Gene using alignment to 6 proteins:

  • PUM2_HUMAN
  • B7ZL34_HUMAN
  • C9JE24_HUMAN
  • C9JW01_HUMAN
  • F2Z366_HUMAN
  • F8WD57_HUMAN

Pseudogenes.org Pseudogenes for PUM2 Gene

genes like me logo Genes that share paralogs with PUM2: view

Variants for PUM2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PUM2 Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
rs34032508 -- p.Asn367Ser

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for PUM2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for PUM2 Gene

Variant ID Type Subtype PubMed ID
esv29979 CNV loss 17803354
esv3328571 CNV insertion 20981092
nsv1005366 CNV loss 25217958
nsv477862 CNV novel sequence insertion 20440878
nsv524207 CNV gain 19592680
nsv999153 CNV loss 25217958

Variation tolerance for PUM2 Gene

Residual Variation Intolerance Score: 1.85% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.08; 21.93% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PUM2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PUM2
Leiden Open Variation Database (LOVD)
PUM2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PUM2 Gene

Disorders for PUM2 Gene

Additional Disease Information for PUM2

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform

No disorders were found for PUM2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PUM2 Gene

Publications for PUM2 Gene

  1. The SNARE-associated component SNAPIN binds PUMILIO2 and NANOS1 proteins in human male germ cells. (PMID: 19168546) Ginter-Matuszewska B … Jaruzelska J (Molecular human reproduction 2009) 3 4 22
  2. Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. (PMID: 12511597) Moore FL … Pera RA (Proceedings of the National Academy of Sciences of the United States of America 2003) 2 3 4
  3. Conservation of a Pumilio-Nanos complex from Drosophila germ plasm to human germ cells. (PMID: 12690449) Jaruzelska J … Reijo Pera RA (Development genes and evolution 2003) 3 4 22
  4. Cloning and comparative sequence analysis of PUM1 and PUM2 genes, human members of the Pumilio family of RNA-binding proteins. (PMID: 12459267) Spassov DS … Jurecic R (Gene 2002) 2 3 4
  5. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T … Nomura N (DNA research : an international journal for rapid publication of reports on genes and genomes 1996) 2 3 4

Products for PUM2 Gene

Sources for PUM2 Gene