The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic d... See more...

Aliases for PTPRR Gene

Aliases for PTPRR Gene

  • Protein Tyrosine Phosphatase Receptor Type R 2 3 5
  • Receptor-Type Tyrosine-Protein Phosphatase R 3 4
  • Protein-Tyrosine Phosphatase PCPTP1 3 4
  • EC 3.1.3.48 4 50
  • NC-PTPCOM1 3 4
  • Ch-1PTPase 3 4
  • R-PTP-R 3 4
  • EC-PTP 2 3
  • PCPTP1 2 3
  • PTP-SL 2 3
  • PTPBR7 2 3
  • PTPRQ 3 4
  • Protein-Tyrosine Phosphatase NC-PTPCOM1 3
  • Protein Tyrosine Phosphatase Cr1PTPase 3
  • Ch-1 PTPase 3
  • PTPRR 5
  • ECPTP 4

External Ids for PTPRR Gene

Previous HGNC Symbols for PTPRR Gene

  • PTPRQ

Previous GeneCards Identifiers for PTPRR Gene

  • GC12M070903
  • GC12M070748
  • GC12M069318
  • GC12M071031
  • GC12M068081

Summaries for PTPRR Gene

Entrez Gene Summary for PTPRR Gene

  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]

GeneCards Summary for PTPRR Gene

PTPRR (Protein Tyrosine Phosphatase Receptor Type R) is a Protein Coding gene. Diseases associated with PTPRR include Deafness, Autosomal Recessive 84A and Refractive Error. Among its related pathways are Signal transduction_Erk Interactions- Inhibition of Erk and MAPK signaling pathway. Gene Ontology (GO) annotations related to this gene include protein kinase binding and protein tyrosine phosphatase activity. An important paralog of this gene is PTPN5.

UniProtKB/Swiss-Prot Summary for PTPRR Gene

  • Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).

Gene Wiki entry for PTPRR Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PTPRR Gene

Genomics for PTPRR Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PTPRR Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH12J070663 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE dbSUPER 250.1 +256.2 256230 1.2 ZNF592 FEZF1 TBP CTCF NRF1 ZNF664 GLIS1 SP7 OSR2 ZNF24 lnc-PTPRB-3 PTPRR FAHD2P1 RF00017-1078 HSALNG0092325 PTPRB
GH12J070755 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE dbSUPER 250.1 +166.3 166337 0.8 IRF2 TAL1 REST ZEB2 ARID1B CBFA2T2 CBFA2T3 ZNF335 PTPRR piR-47086-092 RF00998-032 PTPRB
GH12J070920 Promoter/Enhancer 1.1 EPDnew Ensembl ENCODE 250.7 -0.1 -62 0.4 SIN3A NRF1 EGR1 SP1 RAD21 EZH2 PTPRR HSALNG0092328 LGR5
GH12J070919 Enhancer 0.5 Ensembl 250.7 +1.0 968 0.3 REST SIN3A PKNOX1 ZNF384 MIER2 SP1 ZNF143 PTPRR HSALNG0092327 PTPRB
GH12J070923 Enhancer 0.2 Ensembl 250.7 -0.6 -563 0.2 PTPRR HSALNG0092328 LGR5
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PTPRR on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PTPRR

Top Transcription factor binding sites by QIAGEN in the PTPRR gene promoter:
  • aMEF-2
  • Gfi-1
  • MEF-2A
  • Nkx2-2
  • NRSF form 1
  • NRSF form 2
  • RSRFC4

Genomic Locations for PTPRR Gene

Latest Assembly
chr12:70,638,073-70,920,738
(GRCh38/hg38)
Size:
282,666 bases
Orientation:
Minus strand

Previous Assembly
chr12:71,031,853-71,314,518
(GRCh37/hg19 by Entrez Gene)
Size:
282,666 bases
Orientation:
Minus strand

chr12:71,031,853-71,314,623
(GRCh37/hg19 by Ensembl)
Size:
282,771 bases
Orientation:
Minus strand

Genomic View for PTPRR Gene

Genes around PTPRR on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PTPRR Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PTPRR Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PTPRR Gene

Proteins for PTPRR Gene

  • Protein details for PTPRR Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q15256-PTPRR_HUMAN
    Recommended name:
    Receptor-type tyrosine-protein phosphatase R
    Protein Accession:
    Q15256
    Secondary Accessions:
    • B2R5Z7
    • B7Z3J1
    • F5GXR7
    • O00342
    • Q92682
    • Q9UE65

    Protein attributes for PTPRR Gene

    Size:
    657 amino acids
    Molecular mass:
    73834 Da
    Quaternary structure:
    • Interacts with MAPKs.
    SequenceCaution:
    • Sequence=CAA57957.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=CAB01957.1; Type=Frameshift; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for PTPRR Gene

    Alternative splice isoforms for PTPRR Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PTPRR Gene

Selected DME Specific Peptides for PTPRR Gene

Q15256:
  • LMLDVEE
  • VVHCSAG
  • RYKTILPNP
  • GRTGCFI
  • GPVVVHCS
  • HCSAGIGR
  • LQERRGS

Post-translational modifications for PTPRR Gene

  • Glycosylation at Asn129
  • Modification sites at PhosphoSitePlus

Domains & Families for PTPRR Gene

Gene Families for PTPRR Gene

HGNC:
IUPHAR :
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for PTPRR Gene

Suggested Antigen Peptide Sequences for PTPRR Gene

GenScript: Design optimal peptide antigens:
  • Protein-tyrosine phosphatase PCPTP1 (PTPRR_HUMAN)
  • PTPRR protein (Q05B41_HUMAN)
  • PTPRR protein (Q0VD90_HUMAN)
  • PTPRR protein (Q2TAJ3_HUMAN)
  • PTPRR protein (Q569H9_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q15256

UniProtKB/Swiss-Prot:

PTPRR_HUMAN :
  • Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
Family:
  • Belongs to the protein-tyrosine phosphatase family. Receptor class 7 subfamily.
genes like me logo Genes that share domains with PTPRR: view

Function for PTPRR Gene

Molecular function for PTPRR Gene

UniProtKB/Swiss-Prot Function:
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus (By similarity).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858, ChEBI:CHEBI:82620; EC=3.1.3.48; Evidence={ECO:0000255|PROSITE-ProRule:PRU10044};.

Enzyme Numbers (IUBMB) for PTPRR Gene

Phenotypes From GWAS Catalog for PTPRR Gene

Gene Ontology (GO) - Molecular Function for PTPRR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004721 phosphoprotein phosphatase activity IEA --
GO:0004725 protein tyrosine phosphatase activity TAS 7836467
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS 7836467
GO:0005515 protein binding IPI 10601328
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with PTPRR: view
genes like me logo Genes that share phenotypes with PTPRR: view

Animal Models for PTPRR Gene

MGI Knock Outs for PTPRR:

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTPRR

Clone products for research

  • Addgene plasmids for PTPRR

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PTPRR Gene

Localization for PTPRR Gene

Subcellular locations from UniProtKB/Swiss-Prot for PTPRR Gene

[Isoform Alpha]: Cell membrane. Single-pass type I membrane protein.
[Isoform Delta]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.
[Isoform Gamma]: Cytoplasm, perinuclear region. Note=Locates to the perinuclear areas within the cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PTPRR gene
Compartment Confidence
plasma membrane 5
extracellular 4
cytosol 4
cytoskeleton 2
nucleus 2
endoplasmic reticulum 2
mitochondrion 1
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cell Junctions (3)
  • Cytosol (3)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for PTPRR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space HDA 22664934
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane IDA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with PTPRR: view

Pathways & Interactions for PTPRR Gene

genes like me logo Genes that share pathways with PTPRR: view

Pathways by source for PTPRR Gene

1 Sino Biological pathway for PTPRR Gene
2 BioSystems pathways for PTPRR Gene
1 KEGG pathway for PTPRR Gene
1 GeneGo (Thomson Reuters) pathway for PTPRR Gene
  • Signal transduction_Erk Interactions- Inhibition of Erk
1 Qiagen pathway for PTPRR Gene
  • Epithelial Adherens Junctions

SIGNOR curated interactions for PTPRR Gene

Inactivates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for PTPRR Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001701 in utero embryonic development IEP 10601328
GO:0006470 protein dephosphorylation TAS 7836467
GO:0010633 negative regulation of epithelial cell migration IMP 21724833
GO:0016311 dephosphorylation IEA --
GO:0035335 peptidyl-tyrosine dephosphorylation IEA --
genes like me logo Genes that share ontologies with PTPRR: view

Drugs & Compounds for PTPRR Gene

(3) Drugs for PTPRR Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Water Approved Pharma 0
Phosphate Experimental Pharma 0
genes like me logo Genes that share compounds with PTPRR: view

Transcripts for PTPRR Gene

mRNA/cDNA for PTPRR Gene

4 REFSEQ mRNAs :
22 NCBI additional mRNA sequence :
11 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTPRR

Clone products for research

  • Addgene plasmids for PTPRR

Alternative Splicing Database (ASD) splice patterns (SP) for PTPRR Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b · 14c ^ 15 ^ 16 ^ 17
SP1: - - - - - -
SP2: - - - -
SP3: - - - - -
SP4: -
SP5: -

Relevant External Links for PTPRR Gene

GeneLoc Exon Structure for
PTPRR

Expression for PTPRR Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PTPRR Gene

mRNA differential expression in normal tissues according to GTEx for PTPRR Gene

This gene is overexpressed in Brain - Cerebellum (x8.2), Brain - Cerebellar Hemisphere (x7.5), Brain - Anterior cingulate cortex (BA24) (x5.1), Brain - Cortex (x4.1), and Brain - Frontal Cortex (BA9) (x4.0).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PTPRR

SOURCE GeneReport for Unigene cluster for PTPRR Gene:

Hs.506076

mRNA Expression by UniProt/SwissProt for PTPRR Gene:

Q15256-PTPRR_HUMAN
Tissue specificity: Expressed in brain, placenta, small intestine, stomach, uterus and weakly in the prostate. Isoform alpha has been observed only in the brain. Isoform gamma is expressed in brain, placenta and uterus. Isoform delta is expressed in brain, kidney, placenta, prostate, small intestine and uterus.

Evidence on tissue expression from TISSUES for PTPRR Gene

  • Nervous system(4.7)
  • Intestine(4.4)
  • Kidney(2.3)
  • Adrenal gland(2.1)
genes like me logo Genes that share expression patterns with PTPRR: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTPRR Gene

Orthologs for PTPRR Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PTPRR Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia PTPRR 29 30
  • 99.59 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia PTPRR 29 30
  • 92.22 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia PTPRR 29 30
  • 91.55 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Ptprr 29
  • 86.69 (n)
Mouse
(Mus musculus)
Mammalia Ptprr 29 16 30
  • 86.64 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia PTPRR 30
  • 86 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia PTPRR 30
  • 79 (a)
OneToOne
Chicken
(Gallus gallus)
Aves PTPRR 29 30
  • 78.52 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia PTPRR 30
  • 79 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia ptprr 29
  • 72.8 (n)
African clawed frog
(Xenopus laevis)
Amphibia LOC398636 29
Zebrafish
(Danio rerio)
Actinopterygii PTPRR 30
  • 62 (a)
OneToOne
ptprr 29
  • 61.16 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta CG42327 30
  • 12 (a)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PTP1 30
  • 28 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 35 (a)
OneToMany
Species where no ortholog for PTPRR was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for PTPRR Gene

ENSEMBL:
Gene Tree for PTPRR (if available)
TreeFam:
Gene Tree for PTPRR (if available)
Aminode:
Evolutionary constrained regions (ECRs) for PTPRR: view image
Alliance of Genome Resources:
Additional Orthologs for PTPRR

Paralogs for PTPRR Gene

(41) SIMAP similar genes for PTPRR Gene using alignment to 7 proteins:

  • PTPRR_HUMAN
  • F8VU63_HUMAN
  • F8VVE9_HUMAN
  • Q05B41_HUMAN
  • Q0VD90_HUMAN
  • Q2TAJ3_HUMAN
  • Q569H9_HUMAN

Pseudogenes.org Pseudogenes for PTPRR Gene

genes like me logo Genes that share paralogs with PTPRR: view

Variants for PTPRR Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PTPRR Gene

SNP ID Clinical significance and condition Chr 12 pos Variation AA Info Type
rs144705265 Benign: not provided 70,764,673(-) G/A
NM_002849.4(PTPRR):c.463C>T (p.Arg155Cys)
MISSENSE
rs35387004 -- p.Val386Ile
rs35390084 -- p.Val439Ile
rs35987017 -- p.Tyr249His
rs3803036 -- p.Lys314Arg

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for PTPRR Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for PTPRR Gene

Variant ID Type Subtype PubMed ID
esv1004350 CNV insertion 20482838
esv2082743 CNV deletion 18987734
esv2664329 CNV deletion 23128226
esv2677966 CNV deletion 23128226
esv2746025 CNV deletion 23290073
esv2746026 CNV deletion 23290073
esv2746027 CNV deletion 23290073
esv2746028 CNV deletion 23290073
esv2746032 CNV deletion 23290073
esv32743 CNV gain 17666407
esv3549370 CNV deletion 23714750
esv3629901 CNV loss 21293372
esv3629902 CNV loss 21293372
esv3629903 CNV loss 21293372
esv3629904 CNV loss 21293372
nsv1041247 CNV gain 25217958
nsv1152209 CNV insertion 26484159
nsv436048 CNV insertion 17901297
nsv474136 CNV novel sequence insertion 20440878
nsv509472 CNV insertion 20534489
nsv518982 CNV loss 19592680
nsv53686 CNV deletion 16902084
nsv983347 CNV duplication 23825009

Variation tolerance for PTPRR Gene

Residual Variation Intolerance Score: 68.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.21; 69.88% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PTPRR Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PTPRR
Leiden Open Variation Database (LOVD)
PTPRR

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PTPRR Gene

Disorders for PTPRR Gene

MalaCards: The human disease database

(9) MalaCards diseases for PTPRR Gene - From: COP and GCD

- elite association - COSMIC cancer census association via MalaCards
Search PTPRR in MalaCards View complete list of genes associated with diseases

Additional Disease Information for PTPRR

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with PTPRR: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PTPRR Gene

Publications for PTPRR Gene

  1. Type 2 diabetes locus on 12q15. Further mapping and mutation screening of two candidate genes. (PMID: 11147789) Bektas A … Doria A (Diabetes 2001) 3 4 22
  2. Protein tyrosine phosphatase (PC12, Br7,S1) family: expression characterization in the adult human and mouse. (PMID: 10705342) Augustine KA … Medlock ES (The Anatomical record 2000) 3 4 22
  3. Cloning and expression of PCPTP1 encoding protein tyrosine phosphatase. (PMID: 7557444) Shiozuka K … Kawashima H (Gene 1995) 2 3 4
  4. Human variation in alcohol response is influenced by variation in neuronal signaling genes. (PMID: 20201926) Joslyn G … White RL (Alcoholism, clinical and experimental research 2010) 3 40
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 40

Products for PTPRR Gene

Sources for PTPRR Gene