The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic cataly... See more...

Aliases for PTPRG Gene

Aliases for PTPRG Gene

  • Protein Tyrosine Phosphatase Receptor Type G 2 3 5
  • Receptor-Type Tyrosine-Protein Phosphatase Gamma 3 4
  • EC 4 50
  • RPTPG 2 3
  • PTPG 3 4
  • Protein Tyrosine Phosphatase, Receptor Type, Gamma Polypeptide 3
  • Receptor Type Protein Tyrosine Phosphatase Gamma 3
  • Receptor-Type Protein Phosphatase Gamma 3
  • Receptor Tyrosine Phosphatase Gamma 3
  • Protein Tyrosine Phosphatase Gamma 3
  • Protein-Tyrosine Phosphatase Gamma 4
  • H_RG317H01.1 3
  • R-PTP-Gamma 4
  • HPTPG 3
  • PTPRG 5

External Ids for PTPRG Gene

Previous HGNC Symbols for PTPRG Gene

  • PTPG

Previous GeneCards Identifiers for PTPRG Gene

  • GC03P060412
  • GC03P060949
  • GC03P061402
  • GC03P061504
  • GC03P061522

Summaries for PTPRG Gene

Entrez Gene Summary for PTPRG Gene

  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for PTPRG Gene

PTPRG (Protein Tyrosine Phosphatase Receptor Type G) is a Protein Coding gene. Diseases associated with PTPRG include Infantile Myofibromatosis and Schizoaffective Disorder. Among its related pathways are PAK Pathway. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein tyrosine phosphatase activity. An important paralog of this gene is PTPRZ1.

UniProtKB/Swiss-Prot Summary for PTPRG Gene

Gene Wiki entry for PTPRG Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PTPRG Gene

Genomics for PTPRG Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for PTPRG Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J061558 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 264.9 +0.6 626 6.4 ZNF654 ZNF600 ZNF580 ZMYM3 POLR2A CEBPA ZNF223 ZIC2 CHD4 ZBTB10 PTPRG lnc-FHIT-4 RF00017-3637 C3orf14
GH03J061871 Enhancer 1.2 Ensembl ENCODE CraniofacialAtlas 11.6 +313.1 313132 8.2 ZNF600 ATF2 ATF3 ZIC2 ETS1 TRIM22 ZNF639 CTCF ZNF217 SIN3A PTPRG RNU2-10P RF00951-108 piR-43105-466 C3orf14
GH03J061894 Enhancer 1.1 Ensembl ENCODE 11.6 +333.5 333453 3.2 ZNF207 ZNF600 JUND ZNF580 ATF2 ZNF10 ZSCAN16 NFIC ZIC2 YY1 PTPRG RF00951-108 piR-43105-466 C3orf14
GH03J061903 Enhancer 1 Ensembl ENCODE CraniofacialAtlas 11.6 +341.6 341632 4.4 ZNF600 PAX8 PRDM6 BHLHE40 ZNF24 IKZF1 CSDE1 MNT ZNF366 HLF PTPRG RF00951-108 piR-43105-466 C3orf14
GH03J061649 Enhancer 1 Ensembl ENCODE 11.7 +88.7 88702 1.4 LARP7 ZNF580 ATF2 ZNF10 ZSCAN16 FEZF1 ZNF513 KLF9 ZNF610 ZNF843 PTPRG RPL10AP6 piR-56759-398 LOC107986016 C3orf14
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around PTPRG on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PTPRG

Top Transcription factor binding sites by QIAGEN in the PTPRG gene promoter:
  • C/EBPalpha
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • NF-kappaB
  • NF-kappaB1
  • Spz1

Genomic Locations for PTPRG Gene

Latest Assembly
736,041 bases
Plus strand

Previous Assembly
(GRCh37/hg19 by Entrez Gene)
736,040 bases
Plus strand

(GRCh37/hg19 by Ensembl)
736,046 bases
Plus strand

Genomic View for PTPRG Gene

Genes around PTPRG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PTPRG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PTPRG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PTPRG Gene

Proteins for PTPRG Gene

  • Protein details for PTPRG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Receptor-type tyrosine-protein phosphatase gamma
    Protein Accession:
    Secondary Accessions:
    • B2RU12
    • B7ZLX5
    • Q15623
    • Q59EE0
    • Q68DU5

    Protein attributes for PTPRG Gene

    1445 amino acids
    Molecular mass:
    162003 Da
    Quaternary structure:
    • Monomer; active form. Homodimer; inactive form (Probable). Interacts with CNTN3, CNTN4, CNTN5 and CNTN6.
    • Sequence=BAD93108.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for PTPRG Gene

    Alternative splice isoforms for PTPRG Gene


neXtProt entry for PTPRG Gene

Selected DME Specific Peptides for PTPRG Gene


Post-translational modifications for PTPRG Gene

  • Glycosylation at Asn109, Asn113, Asn156, Asn359, Asn444, Asn619, Asn631, Thr633, Thr640, Thr649, Thr653, Thr656, Thr715, Asn722, and Asn813
  • Modification sites at PhosphoSitePlus
  • Glycosylation from GlyConnect
    • PTPRG_HUMAN (1970)

Other Protein References for PTPRG Gene

Domains & Families for PTPRG Gene

Protein Domains for PTPRG Gene

  • Protein tyrosine phosphatase signature
  • Carbonic anhydrase, eukaryotic

Suggested Antigen Peptide Sequences for PTPRG Gene

GenScript: Design optimal peptide antigens:
  • PTPRG protein (B7ZLX5_HUMAN)
  • Protein tyrosine phosphatase gamma (O60420_HUMAN)
  • Receptor-type tyrosine-protein phosphatase gamma (PTPRG_HUMAN)
  • PTPRG protein (Q49A02_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
  • Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
genes like me logo Genes that share domains with PTPRG: view

Function for PTPRG Gene

Molecular function for PTPRG Gene

UniProtKB/Swiss-Prot Function:
Possesses tyrosine phosphatase activity.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate; Xref=Rhea:RHEA:10684, Rhea:RHEA-COMP:10136, Rhea:RHEA-COMP:10137, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:46858, ChEBI:CHEBI:82620; EC=; Evidence={ECO:0000255|PROSITE-ProRule:PRU10044, ECO:0000269|PubMed:19167335};.
GENATLAS Biochemistry:
protein tyrosine phosphatase,receptor-type,gamma polypeptide,deleted in benign proliferative breast disease,associated with familial breast cancer

Enzyme Numbers (IUBMB) for PTPRG Gene

Phenotypes From GWAS Catalog for PTPRG Gene

Gene Ontology (GO) - Molecular Function for PTPRG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004721 phosphoprotein phosphatase activity IEA --
GO:0004725 protein tyrosine phosphatase activity IBA,IDA 19167335
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS 8382771
GO:0005515 protein binding IPI 19167335
GO:0016787 hydrolase activity IEA --
genes like me logo Genes that share ontologies with PTPRG: view
genes like me logo Genes that share phenotypes with PTPRG: view

Animal Models for PTPRG Gene

MGI Knock Outs for PTPRG:

Animal Models for research

  • Taconic Biosciences Mouse Models for PTPRG

miRNA for PTPRG Gene

miRTarBase miRNAs that target PTPRG

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTPRG

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PTPRG Gene

Localization for PTPRG Gene

Subcellular locations from UniProtKB/Swiss-Prot for PTPRG Gene

Membrane. Single-pass type I membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PTPRG gene
Compartment Confidence
plasma membrane 5
extracellular 4
cytoskeleton 1
mitochondrion 1
peroxisome 1
nucleus 1
endoplasmic reticulum 1
endosome 1
cytosol 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for PTPRG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IEA --
GO:0005887 integral component of plasma membrane TAS 8382771
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070062 extracellular exosome HDA 23533145
genes like me logo Genes that share ontologies with PTPRG: view

Pathways & Interactions for PTPRG Gene

PathCards logo

SuperPathways for PTPRG Gene

SuperPathway Contained pathways
1 PAK Pathway
genes like me logo Genes that share pathways with PTPRG: view

Pathways by source for PTPRG Gene

1 Qiagen pathway for PTPRG Gene
  • Epithelial Adherens Junctions

SIGNOR curated interactions for PTPRG Gene

Gene Ontology (GO) - Biological Process for PTPRG Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006470 protein dephosphorylation IBA 21873635
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway TAS 8382771
GO:0007420 brain development IEA --
GO:0010633 negative regulation of epithelial cell migration IMP 21724833
GO:0010977 negative regulation of neuron projection development IEA --
genes like me logo Genes that share ontologies with PTPRG: view

Drugs & Compounds for PTPRG Gene

(4) Drugs for PTPRG Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Water Approved Pharma 0
Phosphate Experimental Pharma 0
genes like me logo Genes that share compounds with PTPRG: view

Transcripts for PTPRG Gene

mRNA/cDNA for PTPRG Gene

12 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTPRG

Alternative Splicing Database (ASD) splice patterns (SP) for PTPRG Gene

No ASD Table

Relevant External Links for PTPRG Gene

GeneLoc Exon Structure for

Expression for PTPRG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for PTPRG Gene

Protein differential expression in normal tissues from HIPED for PTPRG Gene

This gene is overexpressed in Serum (38.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PTPRG Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PTPRG

SOURCE GeneReport for Unigene cluster for PTPRG Gene:


mRNA Expression by UniProt/SwissProt for PTPRG Gene:

Tissue specificity: Found in a variety of tissues.

Evidence on tissue expression from TISSUES for PTPRG Gene

  • Nervous system(4.7)
  • Bone marrow(4.2)
  • Kidney(2.2)
genes like me logo Genes that share expression patterns with PTPRG: view

Primer products for research

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTPRG Gene

Orthologs for PTPRG Gene

This gene was present in the common ancestor of animals.

Orthologs for PTPRG Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PTPRG 29 30
  • 99.45 (n)
(Canis familiaris)
Mammalia PTPRG 29 30
  • 92.56 (n)
(Monodelphis domestica)
Mammalia PTPRG 30
  • 91 (a)
(Bos Taurus)
Mammalia PTPRG 29 30
  • 90.93 (n)
(Rattus norvegicus)
Mammalia Ptprg 29
  • 89.89 (n)
(Mus musculus)
Mammalia Ptprg 29 16 30
  • 89.41 (n)
(Ornithorhynchus anatinus)
Mammalia PTPRG 30
  • 80 (a)
(Gallus gallus)
Aves PTPRG 29 30
  • 81.59 (n)
(Anolis carolinensis)
Reptilia PTPRG 30
  • 87 (a)
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia ptprg 29
  • 75.13 (n)
(Danio rerio)
Actinopterygii ptprga 29 30
  • 69.87 (n)
ca16b 30
  • 67 (a)
Fruit Fly
(Drosophila melanogaster)
Insecta CG6906 31
  • 35 (a)
Ptp69D 31
  • 32 (a)
Ptp99A 30 31
  • 27 (a)
(Caenorhabditis elegans)
Secernentea ZK616.7 31
  • 37 (a)
M04G7.2 31
  • 36 (a)
C17H12.3 31
  • 34 (a)
F47B3.7 31
  • 33 (a)
ZK484.7 31
  • 32 (a)
K07F5.8 31
  • 32 (a)
K04D7.4 31
  • 32 (a)
C55B7.3 31
  • 31 (a)
T27A3.5 31
  • 31 (a)
F47B3.1 31
  • 30 (a)
F47B3.6 31
  • 30 (a)
F10G8.1 31
  • 28 (a)
Species where no ortholog for PTPRG was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for PTPRG Gene

Gene Tree for PTPRG (if available)
Gene Tree for PTPRG (if available)
Evolutionary constrained regions (ECRs) for PTPRG: view image
Alliance of Genome Resources:
Additional Orthologs for PTPRG

Paralogs for PTPRG Gene

(26) SIMAP similar genes for PTPRG Gene using alignment to 6 proteins:

  • L8E7E6_HUMAN
  • O60420_HUMAN
  • Q49A02_HUMAN
  • Q86TJ8_HUMAN
genes like me logo Genes that share paralogs with PTPRG: view

Variants for PTPRG Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PTPRG Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
rs112710255 Likely Benign: not provided 62,195,130(+) C/T
NM_002841.4(PTPRG):c.1287C>T (p.Asn429=)
rs148186037 Benign: not provided 62,273,025(+) G/A
NM_002841.4(PTPRG):c.3262G>A (p.Val1088Ile)
rs760188470 Likely Benign: not provided 62,157,158(+) A/G
NM_002841.4(PTPRG):c.774A>G (p.Thr258=)
rs763904315 Likely Benign: not provided 62,195,142(+) C/T
NM_002841.4(PTPRG):c.1299C>T (p.Ser433=)
rs7650104 Benign: not provided 62,195,079(+) T/C
NM_002841.4(PTPRG):c.1236T>C (p.His412=)

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for PTPRG Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for PTPRG Gene

Variant ID Type Subtype PubMed ID
dgv1381e212 CNV loss 25503493
dgv1382e212 CNV loss 25503493
dgv4755n100 CNV gain 25217958
dgv895e214 CNV gain 21293372
dgv896e214 CNV gain 21293372
dgv897e214 CNV loss 21293372
esv1001407 CNV deletion 20482838
esv1005605 CNV deletion 20482838
esv1217921 CNV deletion 17803354
esv1631216 CNV deletion 17803354
esv2223333 CNV deletion 18987734
esv22782 CNV loss 19812545
esv23804 CNV loss 19812545
esv2386760 CNV deletion 18987734
esv2548031 CNV insertion 19546169
esv2554644 CNV deletion 19546169
esv2599998 CNV deletion 19546169
esv2658385 CNV deletion 23128226
esv2667638 CNV deletion 23128226
esv2672277 CNV deletion 23128226
esv2673237 CNV deletion 23128226
esv2725334 CNV deletion 23290073
esv2725335 CNV deletion 23290073
esv2725336 CNV deletion 23290073
esv2725337 CNV deletion 23290073
esv2725338 CNV deletion 23290073
esv2759153 CNV gain 17122850
esv3302772 CNV tandem duplication 20981092
esv3384448 CNV insertion 20981092
esv3407063 CNV insertion 20981092
esv35004 CNV gain 17911159
esv3561968 CNV deletion 23714750
esv3561976 CNV deletion 23714750
esv3568804 CNV loss 25503493
esv3568808 CNV loss 25503493
esv3568810 CNV loss 25503493
esv3568811 CNV loss 25503493
esv3568812 CNV loss 25503493
esv3596347 CNV loss 21293372
esv3596349 CNV loss 21293372
esv3596352 CNV loss 21293372
esv3596354 CNV gain 21293372
esv3596357 CNV loss 21293372
esv3596358 CNV loss 21293372
esv3596361 CNV loss 21293372
esv3596362 CNV gain 21293372
esv3596363 CNV loss 21293372
esv3596365 CNV loss 21293372
esv3596368 CNV loss 21293372
esv3596369 CNV loss 21293372
esv3893713 CNV loss 25118596
nsv1000965 CNV gain 25217958
nsv1008615 CNV gain 25217958
nsv1009361 CNV loss 25217958
nsv1012600 CNV gain 25217958
nsv1013884 CNV loss 25217958
nsv1072694 CNV deletion 25765185
nsv1072695 CNV deletion 25765185
nsv1114384 CNV deletion 24896259
nsv1123658 CNV deletion 24896259
nsv1127964 CNV deletion 24896259
nsv1131705 CNV deletion 24896259
nsv1133321 CNV tandem duplication 24896259
nsv1148938 CNV deletion 26484159
nsv236686 CNV deletion 16902084
nsv437862 CNV loss 16468122
nsv460575 CNV gain 19166990
nsv471782 CNV loss 16327809
nsv471908 CNV novel sequence insertion 20440878
nsv478900 CNV novel sequence insertion 20440878
nsv516255 CNV loss 19592680
nsv517920 CNV loss 19592680
nsv522606 CNV loss 19592680
nsv523876 CNV loss 19592680
nsv590438 CNV loss 21841781
nsv590439 CNV loss 21841781
nsv590440 CNV gain 21841781
nsv590441 CNV loss 21841781
nsv822105 CNV gain 20364138
nsv822106 CNV gain 20364138
nsv834711 CNV loss 17160897
nsv834712 CNV gain 17160897
nsv979838 CNV duplication 23825009

Variation tolerance for PTPRG Gene

Residual Variation Intolerance Score: 5.42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.39; 77.03% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for PTPRG Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for
Leiden Open Variation Database (LOVD)

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PTPRG Gene

Disorders for PTPRG Gene

MalaCards: The human disease database

(9) MalaCards diseases for PTPRG Gene - From: COP and GCD

Disorder Aliases PubMed IDs
infantile myofibromatosis
  • lipofibromatosis
schizoaffective disorder
  • schizo-affective psychosis
corneal dystrophy
breast disease
  • breast diseases
lynch syndrome
  • coca 1
- elite association - COSMIC cancer census association via MalaCards
Search PTPRG in MalaCards View complete list of genes associated with diseases

Additional Disease Information for PTPRG

Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with PTPRG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PTPRG Gene

Publications for PTPRG Gene

  1. Structure of the human receptor tyrosine phosphatase gamma gene (PTPRG) and relation to the familial RCC t(3;8) chromosome translocation. (PMID: 8833149) Kastury K … Huebner K (Genomics 1996) 3 4 22
  2. Receptor protein-tyrosine phosphatase gamma is a candidate tumor suppressor gene at human chromosome region 3p21. (PMID: 1711217) LaForgia S … Weston A (Proceedings of the National Academy of Sciences of the United States of America 1991) 2 3 22
  3. Genome-wide association study of recurrent early-onset major depressive disorder. (PMID: 20125088) Shi J … Levinson DF (Molecular psychiatry 2011) 3 40
  4. Genome-wide association study identifies five new schizophrenia loci. (PMID: 21926974) Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (Nature genetics 2011) 3 40
  5. The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules. (PMID: 20133774) Bouyain S … Watkins DJ (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 4

Products for PTPRG Gene

Sources for PTPRG Gene