Aliases for PTPN9 Gene
External Ids for PTPN9 Gene
Previous GeneCards Identifiers for PTPN9 Gene
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008]
GeneCards Summary for PTPN9 Gene
PTPN9 (Protein Tyrosine Phosphatase Non-Receptor Type 9) is a Protein Coding gene. Diseases associated with PTPN9 include Breast Cancer. Among its related pathways are PAK Pathway. Gene Ontology (GO) annotations related to this gene include phosphatase activity and non-membrane spanning protein tyrosine phosphatase activity. An important paralog of this gene is PTPRG.
UniProtKB/Swiss-Prot Summary for PTPN9 Gene
Protein-tyrosine phosphatase that could participate in the transfer of hydrophobic ligands or in functions of the Golgi apparatus.