Aliases for PTPN4 Gene
External Ids for PTPN4 Gene
Previous GeneCards Identifiers for PTPN4 Gene
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008]
GeneCards Summary for PTPN4 Gene
PTPN4 (Protein Tyrosine Phosphatase, Non-Receptor Type 4) is a Protein Coding gene. Among its related pathways are Activated TLR4 signalling and Innate Immune System. Gene Ontology (GO) annotations related to this gene include phosphatase activity and cytoskeletal protein binding. An important paralog of this gene is PTPN3.
UniProtKB/Swiss-Prot for PTPN4 Gene
May act at junctions between the membrane and the cytoskeleton.