Aliases for PTOV1 Gene
External Ids for PTOV1 Gene
Previous GeneCards Identifiers for PTOV1 Gene
This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]
GeneCards Summary for PTOV1 Gene
PTOV1 (PTOV1 Extended AT-Hook Containing Adaptor Protein) is a Protein Coding gene. Diseases associated with PTOV1 include Neuropathy, Hereditary, With Liability To Pressure Palsies. An important paralog of this gene is MED25.
UniProtKB/Swiss-Prot Summary for PTOV1 Gene
May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.