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PTMA (Prothymosin Alpha) is a Protein Coding gene. Diseases associated with PTMA include Hepatitis B and Invasive Malignant Thymoma. Among its related pathways are Validated targets of C-MYC transcriptional activation.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 15607035 |
GO:0033613 | activating transcription factor binding | IPI | 11897665 |
GO:0042393 | histone binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IDA | 8485135 |
GO:0005654 | nucleoplasm | IDA | -- |
GO:0005829 | cytosol | IDA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Validated targets of C-MYC transcriptional activation |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006351 | transcription, DNA-templated | TAS | 10854063 |
GO:0043066 | negative regulation of apoptotic process | IMP | 16478804 |
GO:0043486 | histone exchange | IEA | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
Thymalfasin | Investigational | Pharma | 34 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
---|
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | ||||||||||||||||
SP2: | |||||||||||||||||||
SP3: | - | ||||||||||||||||||
SP4: | - | - |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PTMA 30 |
|
||
Cow (Bos Taurus) |
Mammalia | PTMA 31 31 |
|
OneToMany | |
Mouse (Mus musculus) |
Mammalia | Ptma 31 |
|
OneToMany | |
Gm6625 31 |
|
OneToMany | |||
Dog (Canis familiaris) |
Mammalia | PTMA 30 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Platypus (Ornithorhynchus anatinus) |
Mammalia | PTMA 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PTMA 31 |
|
OneToOne | |
African clawed frog (Xenopus laevis) |
Amphibia | ptma-prov 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | ptma 30 |
|
Disorder | Aliases | PubMed IDs |
---|---|---|
hepatitis b |
|
|
invasive malignant thymoma |
|
|
viral hepatitis |
|
|
thymoma |
|