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Aliases for PTMA Gene
Aliases for PTMA Gene
External Ids for PTMA Gene
- HGNC: 9623
- Entrez Gene: 5757
- Ensembl: ENSG00000187514
- OMIM: 188390
- UniProtKB: P06454
Previous HGNC Symbols for PTMA Gene
- TMSA
Previous GeneCards Identifiers for PTMA Gene
- GC02P230632
- GC02P231306
- GC02P232536
- GC02P232775
- GC02P232398
- GC02P232281
- GC02P232571
Summaries for PTMA Gene
GeneCards Summary for PTMA Gene
PTMA (Prothymosin Alpha) is a Protein Coding gene. Diseases associated with PTMA include Hepatitis B and Invasive Malignant Thymoma. Among its related pathways are Validated targets of C-MYC transcriptional activation.
UniProtKB/Swiss-Prot Summary for PTMA Gene
-
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Additional gene information for PTMA Gene
- HGNC(9623)
- Entrez Gene(5757)
- Ensembl(ENSG00000187514)
- OMIM(188390)
- UniProtKB(P06454)
- Open Targets Platform(ENSG00000187514)
- Monarch Initiative
- Search for PTMA at DataMed
- Search for PTMA at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PTMA Gene
Genomics for PTMA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for PTMA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PTMA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PTMA
- Top Transcription factor binding sites by QIAGEN in the PTMA gene promoter:
-
- Egr-3
- FOXI1
- HFH-3
- HNF-3beta
- Meis-1
- p53
- Pax-4a
- Sp1
- STAT3
Genomic Locations for PTMA Gene
Genomic Locations for PTMA Gene
- chr2:231,706,895-231,713,551
- (GRCh38/hg38)
- Size:
- 6,657 bases
- Orientation:
- Plus strand
- chr2:232,571,605-232,578,251
- (GRCh37/hg19)
- Size:
- 6,647 bases
- Orientation:
- Plus strand
Genomic View for PTMA Gene
Genes around PTMA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q37.1 by HGNC
- 2q37.1 by Entrez Gene
- 2q37.1 by Ensembl
PTMA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PTMA Gene
Proteins for PTMA Gene
-
Protein details for PTMA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P06454-PTMA_HUMAN
- Recommended name:
- Prothymosin alpha
- Protein Accession:
- P06454
- Q15249
- Q15592
Protein attributes for PTMA Gene
- Size:
- 111 amino acids
- Molecular mass:
- 12203 Da
- Quaternary structure:
-
- Interacts with NUPR1; regulates apoptotic process.
Protein Expression for PTMA Gene
Post-translational modifications for PTMA Gene
- Covalently linked to a small RNA of about 20 nucleotides.
-
Ubiquitination at Lys15 and Lys103
- NX_P06454 (NX_P06454-1)
- Modification sites at PhosphoSitePlus
Other Protein References for PTMA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences PTMA / Prothymosin Alplha Antibody and PTMA / Prothymosin Alplha Monoclonal Antibody
- RayBiotech Rabbit anti-Thymosin alpha 1 antibody
- Creative Diagnostics Anti-PTMA (aa 99-111) polyclonal antibody
- Creative Biolabs Recombinant Anti-Human PTMA Antibody
- Novus Biologicals Antibodies for PTMA
-
Abcam antibodies for PTMA
- Invitrogen Antibodies for PTMA (AFLGC-PTMA)
-
Biorbyt antibodies for PTMA
-
Boster Bio Antibodies for PTMA
- Sino Biological Antibodies for PTMA
Protein Products
-
OriGene Purified Proteins for PTMA
- Search Origene for MassSpec and Protein Over-expression Lysates for PTMA
- Origene Custom Protein Services for PTMA
- Novus Biologicals proteins for PTMA
- Sino Biological Recombinant Proteins for PTMA
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for PTMA
-
Abcam proteins for PTMA
Assay Products
- RayBiotech Custom Human PTMA ELISA
- Aviva Systems Biology PTMA ELISA Kit (Human) (OKEH01154) and PTMA ELISA Kit (Human) (OKCD08419)
- antibodies-online: Show 26 available PTMA Elisa Kits ranked by validation data
- Compare Top PTMA Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for PTMA
No data available for DME Specific Peptides for PTMA Gene
Domains & Families for PTMA Gene
Gene Families for PTMA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for PTMA Gene
- InterPro:
- Blocks:
-
- Prothymosin/parathymosin
- ProtoNet:
Suggested Antigen Peptide Sequences for PTMA Gene
- GenScript: Design optimal peptide antigens:
-
- Prothymosin alpha (PTMA_HUMAN)
- Prothymosin alpha (Q15254_HUMAN)
- PTMA protein (Q7KZ52_HUMAN)
- Prothymosin, alpha (Q8TBK9_HUMAN)
- Prothymosin alpha (Q9NYD3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P06454- Family:
-
- Belongs to the pro/parathymosin family.
Function for PTMA Gene
Molecular function for PTMA Gene
- UniProtKB/Swiss-Prot Function:
- Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
- GENATLAS Biochemistry:
- prothymosin alpha,widely expressed,abundant audic nuclear protein potential modulator of the interaction of histone 1 with chromatin
Phenotypes From GWAS Catalog for PTMA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 15607035 |
| GO:0033613 | activating transcription factor binding | IPI | 11897665 |
| GO:0042393 | histone binding | IEA | -- |
Phenotypes for PTMA Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PTMA - Select products 50% OFF >
- * PTMA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PTMA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTMA
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTMA
miRNA for PTMA Gene
- miRTarBase miRNAs that target PTMA
-
- hsa-miR-1-3p (MIRT001343)
- hsa-miR-760 (MIRT036715)
- hsa-miR-744-5p (MIRT037427)
- hsa-miR-423-5p (MIRT038123)
- hsa-miR-130b-5p (MIRT038335)
- hsa-miR-296-3p (MIRT038484)
- hsa-miR-615-3p (MIRT039670)
- hsa-miR-598-3p (MIRT040486)
- hsa-miR-378a-3p (MIRT043921)
- hsa-miR-3613-3p (MIRT087575)
- hsa-miR-4445-5p (MIRT087576)
- hsa-miR-548at-5p (MIRT087578)
- hsa-miR-6128 (MIRT087579)
- hsa-miR-367-5p (MIRT205613)
- hsa-miR-1267 (MIRT205614)
- hsa-miR-4652-3p (MIRT205615)
- hsa-miR-4743-3p (MIRT205616)
- hsa-miR-651-3p (MIRT205619)
- hsa-miR-3148 (MIRT205620)
- hsa-miR-1249-5p (MIRT301135)
- hsa-miR-4795-5p (MIRT301137)
- hsa-miR-5585-3p (MIRT301139)
- hsa-miR-6515-5p (MIRT301140)
- hsa-miR-6797-5p (MIRT301141)
- hsa-miR-6804-5p (MIRT301142)
- hsa-miR-7847-3p (MIRT301143)
- hsa-let-7c-3p (MIRT301144)
- hsa-miR-3163 (MIRT301146)
- hsa-miR-3662 (MIRT301147)
- hsa-miR-4495 (MIRT301148)
- hsa-miR-5587-5p (MIRT301153)
- hsa-miR-129-5p (MIRT301154)
- hsa-miR-153-5p (MIRT301155)
- hsa-miR-329-5p (MIRT301156)
- hsa-miR-616-3p (MIRT301158)
- hsa-miR-624-3p (MIRT301159)
- hsa-miR-1250-3p (MIRT301160)
- hsa-miR-3140-3p (MIRT301161)
- hsa-miR-6755-3p (MIRT301167)
- hsa-miR-6885-3p (MIRT301168)
- hsa-miR-370-5p (MIRT352591)
- hsa-miR-376a-5p (MIRT352592)
- hsa-miR-483-5p (MIRT352593)
- hsa-miR-4329 (MIRT352595)
- hsa-miR-4681 (MIRT352596)
- hsa-miR-4760-5p (MIRT352597)
- hsa-miR-8061 (MIRT352600)
- hsa-miR-889-5p (MIRT407503)
- hsa-miR-5694 (MIRT407505)
- hsa-miR-3919 (MIRT407506)
- hsa-miR-3925-5p (MIRT407507)
- hsa-miR-4303 (MIRT492527)
- hsa-miR-6761-5p (MIRT492528)
- hsa-miR-4251 (MIRT492529)
- hsa-miR-7-2-3p (MIRT498250)
- hsa-miR-7-1-3p (MIRT498251)
- hsa-miR-5692a (MIRT498252)
- hsa-miR-423-3p (MIRT501476)
- hsa-miR-1243 (MIRT501477)
- hsa-miR-3654 (MIRT501478)
- hsa-miR-206 (MIRT501479)
- hsa-miR-613 (MIRT501480)
- hsa-miR-4801 (MIRT546939)
- hsa-miR-4731-3p (MIRT546940)
- hsa-miR-2681-5p (MIRT561712)
- hsa-miR-4520-2-3p (MIRT566202)
- hsa-miR-7152-5p (MIRT566203)
- hsa-miR-4520-3p (MIRT566204)
- hsa-miR-5701 (MIRT566205)
- hsa-miR-5687 (MIRT566206)
- hsa-miR-1468-3p (MIRT566207)
- hsa-miR-1266-3p (MIRT566208)
- hsa-miR-545-3p (MIRT566209)
- hsa-miR-548p (MIRT566210)
- hsa-miR-4773 (MIRT566211)
- hsa-miR-512-5p (MIRT566212)
- hsa-miR-499b-3p (MIRT566213)
- hsa-miR-499a-3p (MIRT566214)
- hsa-miR-4789-3p (MIRT566215)
- hsa-miR-4282 (MIRT566216)
- hsa-miR-377-3p (MIRT566217)
- hsa-miR-629-3p (MIRT566218)
- hsa-miR-4279 (MIRT566219)
- hsa-miR-374b-5p (MIRT566220)
- hsa-miR-374a-5p (MIRT566221)
- hsa-miR-5087 (MIRT566222)
- hsa-miR-5186 (MIRT566223)
- hsa-miR-4725-5p (MIRT566224)
- hsa-miR-29b-1-5p (MIRT566225)
- hsa-miR-4750-3p (MIRT566226)
- hsa-miR-3121-5p (MIRT566227)
- hsa-miR-4671-5p (MIRT566228)
- hsa-miR-1228-3p (MIRT566229)
- hsa-miR-125b-2-3p (MIRT566230)
- hsa-miR-1197 (MIRT566231)
- hsa-miR-6507-3p (MIRT566232)
- hsa-miR-548c-3p (MIRT566233)
- hsa-miR-133a-3p (MIRT566234)
- hsa-miR-133b (MIRT566235)
- hsa-miR-1193 (MIRT735924)
- hsa-miR-1262 (MIRT736672)
- hsa-miR-1293 (MIRT737160)
- hsa-miR-185-5p (MIRT738259)
- hsa-miR-3165 (MIRT740561)
- hsa-miR-3621 (MIRT741755)
- hsa-miR-363-5p (MIRT741841)
- hsa-miR-3656 (MIRT741930)
- hsa-miR-3940-5p (MIRT743146)
- hsa-miR-4306 (MIRT743915)
- hsa-miR-4483 (MIRT745157)
- hsa-miR-4507 (MIRT745552)
- hsa-miR-452-3p (MIRT745830)
- hsa-miR-4644 (MIRT746387)
- hsa-miR-4701-3p (MIRT747296)
- hsa-miR-4734 (MIRT747978)
- hsa-miR-5192 (MIRT749951)
- hsa-miR-5571-5p (MIRT750905)
- hsa-miR-6736-5p (MIRT754215)
- hsa-miR-6740-5p (MIRT754333)
- hsa-miR-6741-5p (MIRT754344)
- hsa-miR-6745 (MIRT754468)
- hsa-miR-6756-5p (MIRT754812)
- hsa-miR-6766-5p (MIRT755120)
- hsa-miR-6839-3p (MIRT757299)
- hsa-miR-6880-5p (MIRT758325)
- hsa-miR-8071 (MIRT760100)
- hsa-miR-92a-1-5p (MIRT760526)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTMA
- Browse OriGene Inhibitory RNA Products For PTMA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTMA
Clone Products
- Applied Biological Materials (abm): Clones for PTMA - Select products 50% OFF >
- * PTMA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PTMA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTMA
Cell Line Products
-
Horizon Cell Lines for PTMA
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PTMA Gene
Localization for PTMA Gene
Subcellular locations from UniProtKB/Swiss-Prot for PTMA Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
- Nucleoplasm (3)
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 8485135 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for PTMA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Validated targets of C-MYC transcriptional activation | ||
Pathways by source for PTMA Gene
1 BioSystems pathway for PTMA Gene
Interacting Proteins for PTMA Gene
Selected Interacting proteins:
P06454-PTMA_HUMAN
ENSP00000344547
for PTMA Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for PTMA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | TAS | 10854063 |
| GO:0043066 | negative regulation of apoptotic process | IMP | 16478804 |
| GO:0043486 | histone exchange | IEA | -- |
Drugs & Compounds for PTMA Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Thymalfasin | Investigational | Pharma | 34 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for PTMA Gene
mRNA/cDNA for PTMA Gene
- 2 REFSEQ mRNAs :
- 21 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000341369 1212 nts (view in UCSC)
- ENST00000409115 1221 nts (view in UCSC)
- ENST00000409321 735 nts (view in UCSC)
- ENST00000409683 933 nts (view in UCSC)
- ENST00000410064 814 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PTMA - Select products 50% OFF >
- * PTMA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PTMA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTMA
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTMA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTMA
- Browse OriGene Inhibitory RNA Products For PTMA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTMA
Clone Products
- Applied Biological Materials (abm): Clones for PTMA - Select products 50% OFF >
- * PTMA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PTMA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTMA
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: | - | ||||||||||||||||||
| SP4: | - | - |
Relevant External Links for PTMA Gene
- GeneLoc Exon Structure for
- PTMA
Expression for PTMA Gene
This gene is overexpressed in Oral epithelium (12.7), Fetal Brain (11.4), and Nasal epithelium (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PTMA Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PTMA
SOURCE GeneReport for Unigene cluster for PTMA Gene:
Hs.459927Evidence on tissue expression from TISSUES for PTMA Gene
- Nervous system(5)
- Skin(4.9)
- Liver(4.9)
- Lung(4.9)
- Eye(4.7)
- Pancreas(4.4)
- Intestine(4.4)
- Blood(4.1)
- Stomach(3.9)
- Kidney(3.8)
- Spleen(3.8)
- Heart(3.3)
- Lymph node(3.3)
- Muscle(3.2)
- Thyroid gland(3)
- Bone marrow(3)
- Bone(3)
- Adrenal gland(2.7)
- Gall bladder(2.7)
Primer Products
-
OriGene qPCR primer pairs for PTMA
-
OriGene qPCR primer pairs and template standards for PTMA
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTMA Gene
Orthologs for PTMA Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | PTMA 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | PTMA 31 31 |
|
OneToMany | |
| Mouse (Mus musculus) |
Mammalia | Ptma 31 |
|
OneToMany | |
| Gm6625 31 |
|
OneToMany | |||
| Dog (Canis familiaris) |
Mammalia | PTMA 30 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | PTMA 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | PTMA 31 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | ptma-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | ptma 30 |
|
- Species where no ortholog for PTMA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for PTMA Gene
- ENSEMBL:
- Gene Tree for PTMA (if available)
- TreeFam:
- Gene Tree for PTMA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PTMA: view image
Paralogs for PTMA Gene
(1) SIMAP similar genes for PTMA Gene using alignment to 11 proteins:
- PTMA_HUMAN
- B8ZZA1_HUMAN
- B8ZZQ6_HUMAN
- B8ZZW7_HUMAN
- F8WCE8_HUMAN
- H7C031_HUMAN
- H7C2N1_HUMAN
- Q15254_HUMAN
- Q7KZ52_HUMAN
- Q8TBK9_HUMAN
- Q9NYD3_HUMAN
No data available for Paralogs for PTMA Gene
Variants for PTMA Gene
Residual Variation Intolerance Score:
54.5% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PTMA Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PTMA
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PTMA Gene
Disorders for PTMA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hepatitis b |
|
|
| invasive malignant thymoma |
|
|
| viral hepatitis |
|
|
| thymoma |
|
Search PTMA in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PTMA
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for PTMA Gene
Publications for PTMA Gene
- Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson DF … Stefansson K (Nature genetics 2008) 3 41
- Effects of zinc binding on the structure and dynamics of the intrinsically disordered protein prothymosin alpha: evidence for metalation as an entropic switch. (PMID: 17929838) Yi S … Choy WY (Biochemistry 2007) 3 23
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4
- Regulation of apoptosis by the p8/prothymosin alpha complex. (PMID: 16478804) Malicet C … Iovanna JL (Proceedings of the National Academy of Sciences of the United States of America 2006) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for PTMA Gene
- Custom Antibody ServicesOriGene Antibodies for PTMA
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PTMA
- Search Origene for MassSpec and Protein Over-expression Lysates for PTMA
- Origene Custom Protein Services for PTMA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTMA
- Browse OriGene Inhibitory RNA Products For PTMA
- OriGene qPCR primer pairs for PTMA
- OriGene qPCR primer pairs and template standards for PTMA
- OriGene CRISPR knockouts for PTMA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PTMA
- Sino Biological Human cDNA Clone for PTMA
- Sino Biological Recombinant Proteins for PTMA
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for PTMA
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for PTMA
- Novus Biologicals proteins for PTMA
- Browse Antibodies
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- Browse Lysates
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- Abcam antibodies for PTMA
- Abcam proteins for PTMA
- Find your target
- Browse Primary Antibodies
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- Search Knockout (KO) Validated Antibodies
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- VectorBuilder Custom and pre-made DNA vectors for PTMA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for PTMA (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for PTMA (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for PTMA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for PTMA
- antibodies-online: Show 39 available PTMA Antibodies ranked by validation data
- Compare Top PTMA Antibodies
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- antibodies-online: Show 26 available PTMA Elisa Kits ranked by validation data
- Compare Top PTMA Elisa Kits
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- antibodies-online: Show 18 available PTMA Proteins ranked by validation data
- Compare Top PTMA Proteins
- Browse Santa Cruz Biotechnology (SCBT) Antibodies
- Search Santa Cruz Biotechnology (SCBT) for PTMA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PTMA
- Horizon Cell Lines for PTMA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTMA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTMA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for PTMA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTMA
- Boster Bio Antibodies for PTMA
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for PTMA
Sources for PTMA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB