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Aliases for PTMA Gene
Aliases for PTMA Gene
External Ids for PTMA Gene
- HGNC: 9623
- Entrez Gene: 5757
- Ensembl: ENSG00000187514
- OMIM: 188390
- UniProtKB: P06454
Previous HGNC Symbols for PTMA Gene
- TMSA
Previous GeneCards Identifiers for PTMA Gene
- GC02P230632
- GC02P231306
- GC02P232536
- GC02P232775
- GC02P232398
- GC02P232281
- GC02P232571
Summaries for PTMA Gene
GeneCards Summary for PTMA Gene
PTMA (Prothymosin Alpha) is a Protein Coding gene. Diseases associated with PTMA include Hepatitis B and Invasive Malignant Thymoma. Among its related pathways are Validated targets of C-MYC transcriptional activation.
UniProtKB/Swiss-Prot Summary for PTMA Gene
-
Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
Additional gene information for PTMA Gene
- Monarch Initiative
- Search for PTMA at DataMed
- Search for PTMA at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for PTMA Gene
Genomics for PTMA Gene
GeneHancer (GH) Regulatory Elements for PTMA Gene
Promoters and enhancers for PTMA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around PTMA on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for PTMA
- Top Transcription factor binding sites by QIAGEN in the PTMA gene promoter:
-
- Egr-3
- FOXI1
- HFH-3
- HNF-3beta
- Meis-1
- p53
- Pax-4a
- Sp1
- STAT3
Genomic Locations for PTMA Gene
Genomic Locations for PTMA Gene
- chr2:231,706,895-231,713,541
- (GRCh38/hg38)
- Size:
- 6,647 bases
- Orientation:
- Plus strand
- chr2:232,571,605-232,578,251
- (GRCh37/hg19)
- Size:
- 6,647 bases
- Orientation:
- Plus strand
Genomic View for PTMA Gene
Genes around PTMA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q37.1 by HGNC
- 2q37.1 by Entrez Gene
- 2q37.1 by Ensembl
PTMA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PTMA Gene
Proteins for PTMA Gene
-
Protein details for PTMA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P06454-PTMA_HUMAN
- Recommended name:
- Prothymosin alpha
- Protein Accession:
- P06454
- Q15249
- Q15592
Protein attributes for PTMA Gene
- Size:
- 111 amino acids
- Molecular mass:
- 12203 Da
- Quaternary structure:
-
- Interacts with NUPR1; regulates apoptotic process.
Protein Expression for PTMA Gene
Post-translational modifications for PTMA Gene
- Covalently linked to a small RNA of about 20 nucleotides.
-
Ubiquitination at Lys15 and Lys103
- NX_P06454 (NX_P06454-1)
- Modification sites at PhosphoSitePlus
Other Protein References for PTMA Gene
Antibody Products
- LifeSpan BioSciences PTMA / Prothymosin Alplha Antibody and PTMA / Prothymosin Alplha Monoclonal Antibody
- RayBiotech Rabbit anti-Thymosin alpha 1 antibody
- Creative Diagnostics Anti-PTMA (aa 99-111) polyclonal antibody
- Creative Biolabs Recombinant Anti-Human PTMA Antibody
- Novus Biologicals Antibodies for PTMA
-
Abcam antibodies for PTMA
- Invitrogen Antibodies for PTMA (AFLGC-PTMA)
- Sino Biological Antibodies for PTMA
Protein Products
-
OriGene Purified Proteins for PTMA
- Search Origene for MassSpec and Protein Over-expression Lysates for PTMA
- Origene Custom Protein Services for PTMA
- Novus Biologicals proteins for PTMA
- Sino Biological Recombinant Proteins for PTMA
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for PTMA
-
Abcam proteins for PTMA
Assay Products
- RayBiotech Custom Human PTMA ELISA
- Aviva Systems Biology PTMA ELISA Kit (Human) (OKEH01154) and PTMA ELISA Kit (Human) (OKCD08419)
- antibodies-online: Show 26 available PTMA Elisa Kits ranked by validation data
- Compare Top PTMA Elisa Kits
-
Quality Products:
-
Signalway ELISA kits for PTMA
No data available for DME Specific Peptides for PTMA Gene
Domains & Families for PTMA Gene
Gene Families for PTMA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for PTMA Gene
- Blocks:
-
- Prothymosin/parathymosin
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for PTMA Gene
- GenScript: Design optimal peptide antigens:
-
- Prothymosin alpha (PTMA_HUMAN)
- Prothymosin alpha (Q15254_HUMAN)
- PTMA protein (Q7KZ52_HUMAN)
- Prothymosin, alpha (Q8TBK9_HUMAN)
- Prothymosin alpha (Q9NYD3_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P06454- Family:
-
- Belongs to the pro/parathymosin family.
Function for PTMA Gene
Molecular function for PTMA Gene
- UniProtKB/Swiss-Prot Function:
- Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections.
- GENATLAS Biochemistry:
- prothymosin alpha,widely expressed,abundant audic nuclear protein potential modulator of the interaction of histone 1 with chromatin
Phenotypes From GWAS Catalog for PTMA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 15607035 |
| GO:0033613 | activating transcription factor binding | IPI | 11897665 |
| GO:0042393 | histone binding | IEA | -- |
Phenotypes for PTMA Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PTMA - Select products 50% OFF >
- * PTMA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PTMA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTMA
- genomics-online: gRNA clones - Search for available PTMA gRNA products
- Overview of 202 available PTMA gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTMA
miRNA for PTMA Gene
- miRTarBase miRNAs that target PTMA
-
- hsa-mir-1-3p (MIRT001343)
- hsa-mir-760 (MIRT036715)
- hsa-mir-744-5p (MIRT037427)
- hsa-mir-423-5p (MIRT038123)
- hsa-mir-130b-5p (MIRT038335)
- hsa-mir-296-3p (MIRT038484)
- hsa-mir-615-3p (MIRT039670)
- hsa-mir-598-3p (MIRT040486)
- hsa-mir-378a-3p (MIRT043921)
- hsa-mir-3613-3p (MIRT087575)
- hsa-mir-4445-5p (MIRT087576)
- hsa-mir-548at-5p (MIRT087578)
- hsa-mir-6128 (MIRT087579)
- hsa-mir-367-5p (MIRT205613)
- hsa-mir-1267 (MIRT205614)
- hsa-mir-4652-3p (MIRT205615)
- hsa-mir-4743-3p (MIRT205616)
- hsa-mir-651-3p (MIRT205619)
- hsa-mir-3148 (MIRT205620)
- hsa-mir-1249-5p (MIRT301135)
- hsa-mir-4795-5p (MIRT301137)
- hsa-mir-5585-3p (MIRT301139)
- hsa-mir-6515-5p (MIRT301140)
- hsa-mir-6797-5p (MIRT301141)
- hsa-mir-6804-5p (MIRT301142)
- hsa-mir-7847-3p (MIRT301143)
- hsa-let-7c-3p (MIRT301144)
- hsa-mir-3163 (MIRT301146)
- hsa-mir-3662 (MIRT301147)
- hsa-mir-4495 (MIRT301148)
- hsa-mir-5587-5p (MIRT301153)
- hsa-mir-129-5p (MIRT301154)
- hsa-mir-153-5p (MIRT301155)
- hsa-mir-329-5p (MIRT301156)
- hsa-mir-616-3p (MIRT301158)
- hsa-mir-624-3p (MIRT301159)
- hsa-mir-1250-3p (MIRT301160)
- hsa-mir-3140-3p (MIRT301161)
- hsa-mir-6755-3p (MIRT301167)
- hsa-mir-6885-3p (MIRT301168)
- hsa-mir-370-5p (MIRT352591)
- hsa-mir-376a-5p (MIRT352592)
- hsa-mir-483-5p (MIRT352593)
- hsa-mir-4329 (MIRT352595)
- hsa-mir-4681 (MIRT352596)
- hsa-mir-4760-5p (MIRT352597)
- hsa-mir-8061 (MIRT352600)
- hsa-mir-889-5p (MIRT407503)
- hsa-mir-5694 (MIRT407505)
- hsa-mir-3919 (MIRT407506)
- hsa-mir-3925-5p (MIRT407507)
- hsa-mir-4303 (MIRT492527)
- hsa-mir-6761-5p (MIRT492528)
- hsa-mir-4251 (MIRT492529)
- hsa-mir-7-2-3p (MIRT498250)
- hsa-mir-7-1-3p (MIRT498251)
- hsa-mir-5692a (MIRT498252)
- hsa-mir-423-3p (MIRT501476)
- hsa-mir-1243 (MIRT501477)
- hsa-mir-3654 (MIRT501478)
- hsa-mir-206 (MIRT501479)
- hsa-mir-613 (MIRT501480)
- hsa-mir-4801 (MIRT546939)
- hsa-mir-4731-3p (MIRT546940)
- hsa-mir-2681-5p (MIRT561712)
- hsa-mir-4520-2-3p (MIRT566202)
- hsa-mir-7152-5p (MIRT566203)
- hsa-mir-4520-3p (MIRT566204)
- hsa-mir-5701 (MIRT566205)
- hsa-mir-5687 (MIRT566206)
- hsa-mir-1468-3p (MIRT566207)
- hsa-mir-1266-3p (MIRT566208)
- hsa-mir-545-3p (MIRT566209)
- hsa-mir-548p (MIRT566210)
- hsa-mir-4773 (MIRT566211)
- hsa-mir-512-5p (MIRT566212)
- hsa-mir-499b-3p (MIRT566213)
- hsa-mir-499a-3p (MIRT566214)
- hsa-mir-4789-3p (MIRT566215)
- hsa-mir-4282 (MIRT566216)
- hsa-mir-377-3p (MIRT566217)
- hsa-mir-629-3p (MIRT566218)
- hsa-mir-4279 (MIRT566219)
- hsa-mir-374b-5p (MIRT566220)
- hsa-mir-374a-5p (MIRT566221)
- hsa-mir-5087 (MIRT566222)
- hsa-mir-5186 (MIRT566223)
- hsa-mir-4725-5p (MIRT566224)
- hsa-mir-29b-1-5p (MIRT566225)
- hsa-mir-4750-3p (MIRT566226)
- hsa-mir-3121-5p (MIRT566227)
- hsa-mir-4671-5p (MIRT566228)
- hsa-mir-1228-3p (MIRT566229)
- hsa-mir-125b-2-3p (MIRT566230)
- hsa-mir-1197 (MIRT566231)
- hsa-mir-6507-3p (MIRT566232)
- hsa-mir-548c-3p (MIRT566233)
- hsa-mir-133a-3p (MIRT566234)
- hsa-mir-133b (MIRT566235)
- hsa-mir-1193 (MIRT735924)
- hsa-mir-1262 (MIRT736672)
- hsa-mir-1293 (MIRT737160)
- hsa-mir-185-5p (MIRT738259)
- hsa-mir-3165 (MIRT740561)
- hsa-mir-3621 (MIRT741755)
- hsa-mir-363-5p (MIRT741841)
- hsa-mir-3656 (MIRT741930)
- hsa-mir-3940-5p (MIRT743146)
- hsa-mir-4306 (MIRT743915)
- hsa-mir-4483 (MIRT745157)
- hsa-mir-4507 (MIRT745552)
- hsa-mir-452-3p (MIRT745830)
- hsa-mir-4644 (MIRT746387)
- hsa-mir-4701-3p (MIRT747296)
- hsa-mir-4734 (MIRT747978)
- hsa-mir-5192 (MIRT749951)
- hsa-mir-5571-5p (MIRT750905)
- hsa-mir-6736-5p (MIRT754215)
- hsa-mir-6740-5p (MIRT754333)
- hsa-mir-6741-5p (MIRT754344)
- hsa-mir-6745 (MIRT754468)
- hsa-mir-6756-5p (MIRT754812)
- hsa-mir-6766-5p (MIRT755120)
- hsa-mir-6839-3p (MIRT757299)
- hsa-mir-6880-5p (MIRT758325)
- hsa-mir-8071 (MIRT760100)
- hsa-mir-92a-1-5p (MIRT760526)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTMA
- Browse OriGene Inhibitory RNA Products For PTMA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTMA
- genomics-online: shRNA clones - Search for available PTMA shRNA products
- Overview of 202 available PTMA gene related products
Clone Products
- Applied Biological Materials (abm): Clones for PTMA - Select products 50% OFF >
- * PTMA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PTMA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTMA
- genomics-online: cdna clones - Search for available PTMA CDNA products
- Overview of 202 available PTMA gene related products
- orf clones - Search for available PTMA ORF products
- Overview of 202 available PTMA gene related products
Cell Line Products
-
Horizon Cell Lines for PTMA
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PTMA Gene
Localization for PTMA Gene
Subcellular locations from UniProtKB/Swiss-Prot for PTMA Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| extracellular | 2 |
| plasma membrane | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
- Nucleoplasm (3)
- Cytosol (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 8485135 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005829 | cytosol | IDA | -- |
Pathways & Interactions for PTMA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Validated targets of C-MYC transcriptional activation | ||
Pathways by source for PTMA Gene
1 BioSystems pathway for PTMA Gene
Interacting Proteins for PTMA Gene
Selected Interacting proteins:
P06454-PTMA_HUMAN
ENSP00000344547
for PTMA Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for PTMA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | TAS | 10854063 |
| GO:0043066 | negative regulation of apoptotic process | IMP | 16478804 |
| GO:0043486 | histone exchange | IEA | -- |
Drugs & Compounds for PTMA Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Thymalfasin | Investigational | Pharma | 29 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for PTMA Gene
mRNA/cDNA for PTMA Gene
- 2 REFSEQ mRNAs :
- 21 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000341369 1212 bps (ENST00000341369.11)
- ENST00000409115 1221 bps (ENST00000409115.7)
- ENST00000409321 735 bps (ENST00000409321.5)
- ENST00000409683 933 bps (ENST00000409683.5)
- ENST00000410064 814 bps (ENST00000410064.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for PTMA - Select products 50% OFF >
- * PTMA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for PTMA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTMA
- genomics-online: gRNA clones - Search for available PTMA gRNA products
- Overview of 202 available PTMA gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTMA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTMA
- Browse OriGene Inhibitory RNA Products For PTMA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTMA
- genomics-online: shRNA clones - Search for available PTMA shRNA products
- Overview of 202 available PTMA gene related products
Clone Products
- Applied Biological Materials (abm): Clones for PTMA - Select products 50% OFF >
- * PTMA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for PTMA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTMA
- genomics-online: cdna clones - Search for available PTMA CDNA products
- Overview of 202 available PTMA gene related products
- orf clones - Search for available PTMA ORF products
- Overview of 202 available PTMA gene related products
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: | - | ||||||||||||||||||
| SP4: | - | - |
Relevant External Links for PTMA Gene
- GeneLoc Exon Structure for
- PTMA
Expression for PTMA Gene
This gene is overexpressed in Oral epithelium (12.7), Fetal Brain (11.4), and Nasal epithelium (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PTMA Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for PTMA
SOURCE GeneReport for Unigene cluster for PTMA Gene:
Hs.459927Evidence on tissue expression from TISSUES for PTMA Gene
- Nervous system(5)
- Liver(4.9)
- Lung(4.9)
- Skin(4.9)
- Eye(4.6)
- Pancreas(4.3)
- Intestine(4.1)
- Blood(3.9)
- Spleen(3.7)
- Stomach(3.7)
- Kidney(3.6)
- Lymph node(2.9)
- Heart(2.8)
- Thyroid gland(2.8)
- Bone marrow(2.7)
- Muscle(2.6)
- Bone(2.4)
- Gall bladder(2.3)
- Adrenal gland(2.2)
Primer Products
-
OriGene qPCR primer pairs for PTMA
-
OriGene qPCR primer pairs and template standards for PTMA
- genomics-online: primer clones - Search for available PTMA Primer products
- Overview of 202 available PTMA gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTMA Gene
Orthologs for PTMA Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LOC101058118 30 |
|
||
| cow (Bos Taurus) |
Mammalia | PTMA 31 31 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Ptma 31 |
|
OneToMany | |
| Gm6625 31 |
|
OneToMany | |||
| dog (Canis familiaris) |
Mammalia | PTMA 31 30 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | PTMA 31 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | PTMA 31 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | ptma-prov 30 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ptma 30 |
|
- Species where no ortholog for PTMA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for PTMA Gene
- ENSEMBL:
- Gene Tree for PTMA (if available)
- TreeFam:
- Gene Tree for PTMA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PTMA: view image
Paralogs for PTMA Gene
(1) SIMAP similar genes for PTMA Gene using alignment to 11 proteins:
- PTMA_HUMAN
- B8ZZA1_HUMAN
- B8ZZQ6_HUMAN
- B8ZZW7_HUMAN
- F8WCE8_HUMAN
- H7C031_HUMAN
- H7C2N1_HUMAN
- Q15254_HUMAN
- Q7KZ52_HUMAN
- Q8TBK9_HUMAN
- Q9NYD3_HUMAN
No data available for Paralogs for PTMA Gene
Variants for PTMA Gene
Residual Variation Intolerance Score:
54.5% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PTMA Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PTMA
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for PTMA Gene
Disorders for PTMA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hepatitis b |
|
|
| invasive malignant thymoma |
|
|
| viral hepatitis |
|
|
| thymoma |
|
Search PTMA in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for PTMA
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for PTMA Gene
Publications for PTMA Gene
- Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson DF … Stefansson K (Nature genetics 2008) 3 41 54
- Effects of zinc binding on the structure and dynamics of the intrinsically disordered protein prothymosin alpha: evidence for metalation as an entropic switch. (PMID: 17929838) Yi S … Choy WY (Biochemistry 2007) 3 23 54
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 54
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Products for PTMA Gene
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- antibodies-online: Show 39 available PTMA Antibodies ranked by validation data
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- Overview of 202 available PTMA gene related products
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