Aliases for PTGFRN Gene
External Ids for PTGFRN Gene
Previous GeneCards Identifiers for PTGFRN Gene
GeneCards Summary for PTGFRN Gene
PTGFRN (Prostaglandin F2 Receptor Inhibitor) is a Protein Coding gene. Diseases associated with PTGFRN include Bone Leiomyosarcoma and Hypotrichosis-Lymphedema-Telangiectasia Syndrome. An important paralog of this gene is IGSF3.
UniProtKB/Swiss-Prot Summary for PTGFRN Gene
Inhibits the binding of prostaglandin F2-alpha (PGF2-alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity). In myoblasts, associates with tetraspanins CD9 and CD81 to prevent myotube fusion during muscle regeneration (By similarity).