Aliases for PTDSS2 Gene
External Ids for PTDSS2 Gene
Previous GeneCards Identifiers for PTDSS2 Gene
The protein encoded by this gene catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine, a structural membrane phospholipid that functions in cell signaling, blood coagulation, and apoptosis. The encoded enzyme also has a high affinity for docosahexaenoic acid (DHA) and can use it to make DHA-containing phosphatidylserine. [provided by RefSeq, Jul 2016]
GeneCards Summary for PTDSS2 Gene
PTDSS2 (Phosphatidylserine Synthase 2) is a Protein Coding gene. Among its related pathways are Glycerophospholipid biosynthesis and Metabolism. Gene Ontology (GO) annotations related to this gene include CDP-diacylglycerol-serine O-phosphatidyltransferase activity. An important paralog of this gene is PTDSS1.
UniProtKB/Swiss-Prot for PTDSS2 Gene
Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. PTDSS2 is specific for phosphatatidylethanolamine and does not act on phosphatidylcholine.