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Aliases for PTCSC2 Gene

Subcategory (RNA class) for PTCSC2 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for PTCSC2 Gene

  • Papillary Thyroid Carcinoma Susceptibility Candidate 2 (Non-Protein Coding) 2 3 5

External Ids for PTCSC2 Gene

Summaries for PTCSC2 Gene

GeneCards Summary for PTCSC2 Gene

PTCSC2 (Papillary Thyroid Carcinoma Susceptibility Candidate 2 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for PTCSC2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PTCSC2 Gene

Genomics for PTCSC2 Gene

GeneHancer (GH) Regulatory Elements for PTCSC2 Gene

Promoters and enhancers for PTCSC2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I097856 Promoter 0.8 EPDnew 550.8 -0.5 -452 0.1 ZNF202 USF1 SUZ12 USF2 E2F6 EZH2 PTCSC2 FOXE1 ZNF782 NCBP1 LOC441454 TSTD2 MFSD14C ZNF322P1 GC09P097870
GH09I097853 Promoter 0.6 EPDnew 550.8 -0.1 -116 0.1 EZH2 FOXE1 PTCSC2
GH09I097855 Enhancer 0.6 ENCODE 550.8 -1.1 -1061 0.2 CTCF L3MBTL2 SUZ12 ZNF10 SIN3A ZBTB8A ZNF335 POLR2A GLIS1 SCRT2 PTCSC2 FOXE1 GC09P097870
GH09I097852 Enhancer 0.4 ENCODE 550.8 +0.9 929 0.1 SUZ12 EZH2 FOXE1 PTCSC2 ENSG00000260677
GH09I097854 Enhancer 0.4 ENCODE 550.8 +0.6 559 0 CTBP2 EZH2 FOXE1 PTCSC2 ENSG00000260677
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around PTCSC2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for PTCSC2 Gene

Genomic Locations for PTCSC2 Gene
chr9:97,709,920-97,853,093
(GRCh38/hg38)
Size:
143,174 bases
Orientation:
Minus strand
chr9:100,568,217-100,572,290
(GRCh37/hg19)

Genomic View for PTCSC2 Gene

Genes around PTCSC2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PTCSC2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PTCSC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for PTCSC2 Gene

Proteins for PTCSC2 Gene

Post-translational modifications for PTCSC2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PTCSC2 Gene

Domains & Families for PTCSC2 Gene

Gene Families for PTCSC2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PTCSC2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PTCSC2 Gene

Function for PTCSC2 Gene

Phenotypes From GWAS Catalog for PTCSC2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PTCSC2 Gene

Localization for PTCSC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PTCSC2 Gene

Pathways & Interactions for PTCSC2 Gene

SuperPathways for PTCSC2 Gene

No Data Available

Interacting Proteins for PTCSC2 Gene

Gene Ontology (GO) - Biological Process for PTCSC2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PTCSC2 Gene

Drugs & Compounds for PTCSC2 Gene

No Compound Related Data Available

Transcripts for PTCSC2 Gene

mRNA/cDNA for PTCSC2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for PTCSC2 Gene

No ASD Table

Relevant External Links for PTCSC2 Gene

GeneLoc Exon Structure for
PTCSC2
ECgene alternative splicing isoforms for
PTCSC2

Expression for PTCSC2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PTCSC2 Gene

NURSA nuclear receptor signaling pathways regulating expression of PTCSC2 Gene:

PTCSC2
genes like me logo Genes that share expression patterns with PTCSC2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTCSC2 Gene

Orthologs for PTCSC2 Gene

Evolution for PTCSC2 Gene

ENSEMBL:
Gene Tree for PTCSC2 (if available)
TreeFam:
Gene Tree for PTCSC2 (if available)

No data available for Orthologs for PTCSC2 Gene

Paralogs for PTCSC2 Gene

No data available for Paralogs for PTCSC2 Gene

Variants for PTCSC2 Gene

Additional Variant Information for PTCSC2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PTCSC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for PTCSC2 Gene

Disorders for PTCSC2 Gene

Additional Disease Information for PTCSC2

No disorders were found for PTCSC2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PTCSC2 Gene

Publications for PTCSC2 Gene

  1. Genetic predisposition to papillary thyroid carcinoma: involvement of FOXE1, TSHR, and a novel lincRNA gene, PTCSC2. (PMID: 25303483) He H … de la Chapelle A (The Journal of clinical endocrinology and metabolism 2015) 2 3 58
  2. A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. (PMID: 23408906) Porcu E … Naitza S (PLoS genetics 2013) 2 3 58
  3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E … Simpson AJ (Proceedings of the National Academy of Sciences of the United States of America 2000) 3 58
  4. MYH9 binds to lncRNA gene PTCSC2 and regulates FOXE1 in the 9q22 thyroid cancer risk locus. (PMID: 28049826) Wang Y … de la Chapelle A (Proceedings of the National Academy of Sciences of the United States of America 2017) 3

Products for PTCSC2 Gene

Sources for PTCSC2 Gene

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