External Ids for PTCD1 Gene
Previous GeneCards Identifiers for PTCD1 Gene
This gene encodes a mitochondrial protein that binds leucine tRNAs and other mitochondrial RNAs and plays a role in the regulation of translation. Increased expression of this gene results in decreased mitochondrial leucine tRNA levels. Naturally occurring read-through transcription exists between upstream ATP5J2 (ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2) and this gene. [provided by RefSeq, Aug 2015]
GeneCards Summary for PTCD1 Gene
PTCD1 (Pentatricopeptide Repeat Domain 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include tRNA binding. An important paralog of this gene is ATP5MF-PTCD1.
UniProtKB/Swiss-Prot for PTCD1 Gene
Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria-encoded proteins and COX activity. Affects also the 3-processing of mitochondrial tRNAs.