Aliases for PTBP3 Gene
Aliases for PTBP3 Gene
- Polypyrimidine Tract Binding Protein 3 2 3 5
- Regulator Of Differentiation 1 3 4
- ROD1 3 4
- ROD1 Regulator Of Differentiation 1 (S. Pombe) 2
- Regulator Of Differentiation (In S. Pombe) 1 2
- Fission Yeast Differentiation Regulator 3
- Polypyrimidine Tract-Binding Protein 3 3
- ROD1 Regulator Of Differentiation 1 3
- Rod1 4
External Ids for PTBP3 Gene
- HGNC: 10253
- Entrez Gene: 9991
- Ensembl: ENSG00000119314
- OMIM: 607527
- UniProtKB: O95758
Previous HGNC Symbols for PTBP3 Gene
- ROD1
Previous GeneCards Identifiers for PTBP3 Gene
- GC09M114981
Summaries for PTBP3 Gene
-
The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for PTBP3 Gene
PTBP3 (Polypyrimidine Tract Binding Protein 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is PTBP1.
UniProtKB/Swiss-Prot for PTBP3 Gene
-
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PTBP3 Gene
Genomics for PTBP3 Gene
GeneHancer (GH) Regulatory Elements for PTBP3 Gene
Promoters and enhancers for PTBP3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around PTBP3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for PTBP3 Gene
Genomic Locations for PTBP3 Gene
- chr9:112,217,715-112,333,667
- (GRCh38/hg38)
- Size:
- 115,953 bases
- Orientation:
- Minus strand
- chr9:114,980,715-115,095,947
- (GRCh37/hg19)
Genomic View for PTBP3 Gene
Genes around PTBP3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 9q32 by Entrez Gene
- 9q32 by HGNC
- 9q32 by Ensembl
PTBP3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PTBP3 Gene
Proteins for PTBP3 Gene
-
Protein details for PTBP3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95758-PTBP3_HUMAN
- Recommended name:
- Polypyrimidine tract-binding protein 3
- Protein Accession:
- O95758
- B1ALY2
- B1ALY3
- B1ALY5
- B1ALY6
- B3KME7
- Q68DB9
- Q86YB3
- Q86YH9
Protein attributes for PTBP3 Gene
- Size:
- 552 amino acids
- Molecular mass:
- 59690 Da
- Quaternary structure:
-
- Interacts with THBS4 (via the acidic amphipathic C-terminus).
- SequenceCaution:
-
- Sequence=AAH39896.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA75466.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BI463123; Type=Frameshift; Positions=92; Evidence={ECO:0000305};
Protein Expression for PTBP3 Gene
Post-translational modifications for PTBP3 Gene
Other Protein References for PTBP3 Gene
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for PTBP3
- Novus Biologicals Antibodies for PTBP3
- Invitrogen Antibodies for PTBP3
- GeneTex PTBP3 Antibody for PTBP3
-
Boster Bio Antibodies for PTBP3
-
Santa Cruz Biotechnology (SCBT) Antibodies for PTBP3
Protein Products
-
OriGene Purified Proteins for PTBP3
- Search Origene for MassSpec and Protein Over-expression Lysates for PTBP3
- Origene Custom Protein Services for PTBP3
- antibodies-online: Search results for 4 available PTBP3 Proteins ranked by validation data
- Compare Top PTBP3 Proteins
-
Quality Products:
- Search GeneTex for Proteins for PTBP3
Assay Products
No data available for DME Specific Peptides for PTBP3 Gene
Domains & Families for PTBP3 Gene
Gene Families for PTBP3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PTBP3 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for PTBP3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for PTBP3 Gene
Function for PTBP3 Gene
Molecular function for PTBP3 Gene
- UniProtKB/Swiss-Prot Function:
- RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Phenotypes From GWAS Catalog for PTBP3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | TAS,HDA | 22658674 |
Phenotypes for PTBP3 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PTBP3
-
CRISPR Products
-
OriGene CRISPR knockouts for PTBP3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTBP3
- genomics-online: gRNA clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- Applied Biological Materials CRISPR for PTBP3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTBP3
- GenScript: Design CRISPR guide RNA sequences for PTBP3
miRNA for PTBP3 Gene
- miRTarBase miRNAs that target PTBP3
-
- hsa-mir-124-3p (MIRT022729)
- hsa-mir-221-3p (MIRT024160)
- hsa-mir-21-5p (MIRT030890)
- hsa-mir-1229-3p (MIRT036365)
- hsa-mir-484 (MIRT041782)
- hsa-mir-324-3p (MIRT042966)
- hsa-mir-30c-5p (MIRT047996)
- hsa-mir-197-3p (MIRT048115)
- hsa-mir-210-3p (MIRT054186)
- hsa-mir-181a-5p (MIRT106868)
- hsa-mir-181b-5p (MIRT106869)
- hsa-mir-181c-5p (MIRT106870)
- hsa-mir-181d-5p (MIRT106872)
- hsa-mir-4262 (MIRT106875)
- hsa-mir-7154-5p (MIRT106878)
- hsa-mir-373-5p (MIRT323959)
- hsa-mir-616-5p (MIRT323960)
- hsa-mir-371b-5p (MIRT323962)
- hsa-mir-205-3p (MIRT364362)
- hsa-mir-3613-3p (MIRT393731)
- hsa-mir-548x-3p (MIRT534937)
- hsa-mir-548j-3p (MIRT534938)
- hsa-mir-548aq-3p (MIRT534939)
- hsa-mir-548am-3p (MIRT534940)
- hsa-mir-548aj-3p (MIRT534941)
- hsa-mir-548ah-3p (MIRT534942)
- hsa-mir-548ae-3p (MIRT534943)
- hsa-mir-5089-3p (MIRT555168)
- hsa-mir-580-3p (MIRT555169)
- hsa-mir-222-3p (MIRT555170)
- hsa-mir-548v (MIRT555171)
- hsa-mir-187-5p (MIRT555172)
- hsa-mir-891b (MIRT555173)
- hsa-mir-15b-3p (MIRT555174)
- hsa-mir-8060 (MIRT555175)
- hsa-mir-4728-3p (MIRT555176)
- hsa-mir-4712-3p (MIRT555177)
- hsa-mir-4672 (MIRT566238)
- hsa-mir-5582-5p (MIRT566239)
- hsa-mir-6768-5p (MIRT566240)
- hsa-mir-3910 (MIRT566241)
- hsa-mir-3714 (MIRT566242)
- hsa-mir-506-3p (MIRT566243)
- hsa-mir-6772-3p (MIRT630576)
- hsa-mir-4448 (MIRT630577)
- hsa-mir-4268 (MIRT630578)
- hsa-mir-548o-3p (MIRT630579)
- hsa-mir-1323 (MIRT630580)
- hsa-mir-4496 (MIRT630581)
- hsa-mir-6835-3p (MIRT630582)
- hsa-mir-377-3p (MIRT666780)
- hsa-mir-3941 (MIRT666781)
- hsa-mir-603 (MIRT666782)
- hsa-mir-8485 (MIRT666783)
- hsa-mir-607 (MIRT722098)
- hsa-mir-29b-2-5p (MIRT722099)
- hsa-mir-6715b-3p (MIRT722100)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTBP3
- Browse OriGene Inhibitory RNA Products For PTBP3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTBP3
- genomics-online: shRNA clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
Clone Products
- Sino Biological Human cDNA Clone for PTBP3
- VectorBuilder custom plasmid, inducible vectors for PTBP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PTBP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTBP3
- Applied Biological Materials Clones for PTBP3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PTBP3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PTBP3 Gene
Localization for PTBP3 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 4 |
| cytoskeleton | 2 |
| plasma membrane | 1 |
| peroxisome | 1 |
| cytosol | 1 |
- Nucleus (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for PTBP3 Gene
Pathways & Interactions for PTBP3 Gene
No Data Available
Interacting Proteins for PTBP3 Gene
Selected Interacting proteins:
O95758-PTBP3_HUMAN
ENSP00000334499
for PTBP3 Gene via
IID
MINT
STRING
GPS-Prot Interaction Network for PTBP3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006397 | mRNA processing | IEA | -- |
| GO:0008380 | RNA splicing | IEA | -- |
| GO:0009653 | anatomical structure morphogenesis | TAS | 10207106 |
| GO:0030154 | cell differentiation | IEA | -- |
| GO:0033119 | negative regulation of RNA splicing | IDA | 18335065 |
No data available for Pathways by source and SIGNOR curated interactions for PTBP3 Gene
Transcripts for PTBP3 Gene
mRNA/cDNA for PTBP3 Gene
- (402) Selected AceView cDNA sequences:
- (7) Additional mRNA sequences :
- (10) REFSEQ mRNAs :
- (8) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000210227 734 bps (uc064vce.1)
- ENST00000334318 7990 bps (uc004bfx.4)
- ENST00000343327 2755 bps (uc004bfy.4)
- ENST00000374255 3413 bps (uc004bfw.4)
- ENST00000374257 7240 bps (uc011lwu.3)
Unigene Clusters for PTBP3 Gene
- Polypyrimidine tract binding protein 3:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for PTBP3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTBP3
- genomics-online: gRNA clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- Applied Biological Materials CRISPR for PTBP3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PTBP3
- GenScript: Design CRISPR guide RNA sequences for PTBP3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTBP3
- Browse OriGene Inhibitory RNA Products For PTBP3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTBP3
- genomics-online: shRNA clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
Clone Products
- Sino Biological Human cDNA Clone for PTBP3
- VectorBuilder custom plasmid, inducible vectors for PTBP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PTBP3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTBP3
- Applied Biological Materials Clones for PTBP3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | · | 8c | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP8: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP9: |
| ExUns: | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||
| SP2: | |||||||||||
| SP3: | |||||||||||
| SP4: | |||||||||||
| SP5: | |||||||||||
| SP6: | |||||||||||
| SP7: | |||||||||||
| SP8: | |||||||||||
| SP9: |
Expression for PTBP3 Gene
mRNA differential expression in normal tissues according to GTEx for PTBP3 Gene
This gene is overexpressed in Whole Blood (x4.5).
This gene is overexpressed in CD8 Tcells (9.6), Lymph node (7.4), and Monocytes (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PTBP3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PTBP3 Gene:
PTBP3SOURCE GeneReport for Unigene cluster for PTBP3 Gene:
Hs.269988mRNA Expression by UniProt/SwissProt for PTBP3 Gene:
O95758-PTBP3_HUMAN
Tissue specificity:
Expressed in several hematopoietic cell lines examined.
Evidence on tissue expression from TISSUES for PTBP3 Gene
- Intestine(2.7)
- Lung(2.2)
- Kidney(2)
- Skin(2)
Primer Products
-
OriGene qPCR primer pairs for PTBP3
-
OriGene qPCR primer pairs and template standards for PTBP3
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for PTBP3 Gene
Orthologs for PTBP3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ROD1 33 |
|
||
| PTBP3 34 |
|
OneToOne | |||
| cow (Bos Taurus) |
Mammalia | PTBP3 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| rat (Rattus norvegicus) |
Mammalia | Ptbp3 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Ptbp3 16 34 33 |
|
||
| dog (Canis familiaris) |
Mammalia | PTBP3 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | PTBP3 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ROD1 33 |
|
||
| PTBP3 34 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | PTBP3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | ptbp3 33 |
|
||
| Str.13021 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | ptbp3 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | heph 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | ptb-1 34 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToMany |
- Species where no ortholog for PTBP3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for PTBP3 Gene
- ENSEMBL:
- Gene Tree for PTBP3 (if available)
- TreeFam:
- Gene Tree for PTBP3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PTBP3: view image
Paralogs for PTBP3 Gene
Variants for PTBP3 Gene
| SNP ID | Clin | Chr 09 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000031079 | -- | 112,332,247(-) | C/A | intron_variant | |
| rs1000044660 | -- | 112,325,613(-) | G/A/T | intron_variant | |
| rs1000045806 | -- | 112,303,427(-) | A/T | intron_variant | |
| rs1000051948 | -- | 112,322,154(-) | /G | intron_variant | |
| rs1000104790 | -- | 112,264,176(-) | A/G | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2279381 | CNV | deletion | 18987734 |
| esv2461102 | CNV | deletion | 19546169 |
| esv2662225 | CNV | deletion | 23128226 |
| esv2672483 | CNV | deletion | 23128226 |
| esv2738946 | CNV | deletion | 23290073 |
| esv3621510 | CNV | loss | 21293372 |
| esv3621511 | CNV | gain | 21293372 |
| esv3621512 | CNV | loss | 21293372 |
| nsv1035315 | CNV | gain | 25217958 |
| nsv1053706 | CNV | loss | 25217958 |
| nsv1124464 | CNV | deletion | 24896259 |
| nsv1129305 | CNV | insertion | 24896259 |
| nsv466487 | CNV | loss | 19166990 |
| nsv511430 | CNV | loss | 21212237 |
| nsv518422 | CNV | gain | 19592680 |
| nsv615196 | CNV | loss | 21841781 |
| nsv825045 | CNV | loss | 20364138 |
| nsv950926 | CNV | duplication | 24416366 |
Residual Variation Intolerance Score:
28.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.42;
27.95% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PTBP3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PTBP3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PTBP3 Gene
Disorders for PTBP3 Gene
Additional Disease Information for PTBP3
No disorders were found for PTBP3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PTBP3 Gene
Publications for PTBP3 Gene
- Isolation of a mammalian homologue of a fission yeast differentiation regulator. (PMID: 10207106) Yamamoto H … Okayama H (Molecular and cellular biology 1999) 2 3 4 22 58
- Regulator of differentiation 1 (ROD1) binds to the amphipathic C-terminal peptide of thrombospondin-4 and is involved in its mitogenic activity. (PMID: 19441079) Sadvakassova G … Congote LF (Journal of cellular physiology 2009) 3 4 58
- Expression of human nPTB is limited by extreme suboptimal codon content. (PMID: 18335065) Robinson F … Smith CW (PloS one 2008) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
Products for PTBP3 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for PTBP3
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for PTBP3
- Search Origene for MassSpec and Protein Over-expression Lysates for PTBP3
- Origene Custom Protein Services for PTBP3
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PTBP3
- Browse OriGene Inhibitory RNA Products For PTBP3
- OriGene qPCR primer pairs for PTBP3
- OriGene qPCR primer pairs and template standards for PTBP3
- OriGene CRISPR knockouts for PTBP3
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For PTBP3
- GenScript: Next-day shipping of latest version cDNA ORF clones for PTBP3 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for PTBP3
- GenScript Custom Assay Services for PTBP3
- GenScript Custom overexpressing Cell Line Services for PTBP3
- GenScript: Design CRISPR guide RNA sequences for PTBP3
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for PTBP3
- Sino Biological Human cDNA Clone for PTBP3
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for PTBP3
- Novus Biologicals proteins and lysates for PTBP3
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for PTBP3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PTBP3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 46 available PTBP3 Antibodies ranked by validation data
- Compare Top PTBP3 Antibodies
- antibodies-online: Search results for available PTBP3 related products ranked by validation data
- antibodies-online: Search results for 4 available PTBP3 Proteins ranked by validation data
- Compare Top PTBP3 Proteins
- Quality Products:
- GeneTex PTBP3 Antibody for PTBP3
- Search GeneTex for Proteins for PTBP3
- Santa Cruz Biotechnology (SCBT) Antibodies for PTBP3
- Search Santa Cruz Biotechnology (SCBT) for PTBP3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PTBP3
- Horizon Cell Lines for PTBP3
- genomics-online: cdna clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- orf clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- genomics-online: gRNA clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- genomics-online: primer clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- genomics-online: shRNA clones - Search results for 100 available PTBP3 gene related products
- Overview of 100 available PTBP3 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PTBP3
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PTBP3
- GeneCopoeia miRNA 3'UTR Target clone products for PTBP3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PTBP3
- Boster Bio Antibodies for PTBP3
- Browse Boster Bio ELISA Kits
Sources for PTBP3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio