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Aliases for PSORS1C3 Gene

Subcategory (RNA class) for PSORS1C3 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for PSORS1C3 Gene

  • Psoriasis Susceptibility 1 Candidate 3 (Non-Protein Coding) 2 3 5
  • Psoriasis Susceptibility 1 Candidate 3 2
  • Non-Protein Coding RNA 196 2
  • NCRNA00196 3

External Ids for PSORS1C3 Gene

Previous GeneCards Identifiers for PSORS1C3 Gene

  • GC00U991169
  • GC06U900577
  • GC06M031250
  • GC06M031142
  • GC06M031143
  • GC06M031267
  • GC06M031302
  • GC06M031358

Summaries for PSORS1C3 Gene

GeneCards Summary for PSORS1C3 Gene

PSORS1C3 (Psoriasis Susceptibility 1 Candidate 3 (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with PSORS1C3 include Psoriasis.

Additional gene information for PSORS1C3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PSORS1C3 Gene

Genomics for PSORS1C3 Gene

GeneHancer (GH) Regulatory Elements for PSORS1C3 Gene

Promoters and enhancers for PSORS1C3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I031178 Enhancer 0.4 Ensembl 584.7 -1.0 -1002 0.2 NFIC IKZF1 JUNB PSORS1C3 POU5F1 PIR57491
GH06I031269 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 32.6 -93.6 -93562 4.4 HDGF PKNOX1 ATF1 SMAD1 ARID4B SIN3A GLI4 ZNF2 IRF4 YY1 HLA-C PIR41455 PSORS1C3 PPT2 TNXB LSM2 PSORS1C2 HCG18 HCG27 ENSG00000229836
GH06I031196 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 33.6 -20.0 -19999 3.1 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 ZNF548 SP3 NFYC ZNF610 ENSG00000272501 GC06M031194 HCG27 PSORS1C3 POU5F1 PSORS1C2 PRRT1 CCHCR1 HLA-C GNL1
GH06I031202 Promoter/Enhancer 1.7 Ensembl ENCODE dbSUPER 29.4 -26.4 -26424 4.6 HDGF PKNOX1 CLOCK FOXA2 ARNT ZFP64 ARID4B NEUROD1 SIN3A DMAP1 PSORS1C3 ENSG00000272501 HLA-C PSORS1C2 POU5F1 PSORS1C1 MICB MICA-AS1 SKIV2L ENSG00000271821
GH06I031185 Enhancer 1.3 Ensembl ENCODE dbSUPER 34.7 -8.6 -8649 2.5 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 ZNF48 RXRA NFYC MXD4 GC06M031181 ENSG00000272501 PSORS1C3 POU5F1 PSORS1C2 CCHCR1 PSORS1C1 MICB MICA HCG22
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around PSORS1C3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the PSORS1C3 gene promoter:

Genomic Locations for PSORS1C3 Gene

Genomic Locations for PSORS1C3 Gene
4,165 bases
Minus strand

Genomic View for PSORS1C3 Gene

Genes around PSORS1C3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PSORS1C3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PSORS1C3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for PSORS1C3 Gene

Post-translational modifications for PSORS1C3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PSORS1C3 Gene

Domains & Families for PSORS1C3 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PSORS1C3 Gene

Function for PSORS1C3 Gene

Phenotypes From GWAS Catalog for PSORS1C3 Gene

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PSORS1C3 Gene

Localization for PSORS1C3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for PSORS1C3 Gene

Pathways & Interactions for PSORS1C3 Gene

SuperPathways for PSORS1C3 Gene

No Data Available

Interacting Proteins for PSORS1C3 Gene

Gene Ontology (GO) - Biological Process for PSORS1C3 Gene


No data available for Pathways by source and SIGNOR curated interactions for PSORS1C3 Gene

Drugs & Compounds for PSORS1C3 Gene

(1) Drugs for PSORS1C3 Gene - From: PharmGKB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Allopurinol Approved Pharma 154
genes like me logo Genes that share compounds with PSORS1C3: view

Transcripts for PSORS1C3 Gene

mRNA/cDNA for PSORS1C3 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PSORS1C3 Gene

Psoriasis susceptibility 1 candidate 3 (non-protein coding):
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PSORS1C3 Gene

No ASD Table

Relevant External Links for PSORS1C3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PSORS1C3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PSORS1C3 Gene

mRNA differential expression in normal tissues according to GTEx for PSORS1C3 Gene

This gene is overexpressed in Bladder (x7.8) and Pancreas (x6.0).

NURSA nuclear receptor signaling pathways regulating expression of PSORS1C3 Gene:


SOURCE GeneReport for Unigene cluster for PSORS1C3 Gene:

genes like me logo Genes that share expression patterns with PSORS1C3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PSORS1C3 Gene

Orthologs for PSORS1C3 Gene

Evolution for PSORS1C3 Gene

Gene Tree for PSORS1C3 (if available)
Gene Tree for PSORS1C3 (if available)

No data available for Orthologs for PSORS1C3 Gene

Paralogs for PSORS1C3 Gene

No data available for Paralogs for PSORS1C3 Gene

Variants for PSORS1C3 Gene

Sequence variations from dbSNP and Humsavar for PSORS1C3 Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000887637 -- 31,178,738(-) G/A upstream_transcript_variant
rs1001394824 -- 31,174,455(-) C/A intron_variant
rs1001811341 -- 31,179,376(-) C/T upstream_transcript_variant
rs1002242370 -- 31,177,824(-) C/G non_coding_transcript_variant
rs1002500826 -- 31,176,335(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for PSORS1C3 Gene

Variant ID Type Subtype PubMed ID
nsv601481 CNV loss 21841781
nsv601264 CNV loss 21841781
nsv525933 CNV loss 19592680
nsv428140 CNV gain+loss 18775914
nsv1144137 CNV deletion 24896259
nsv1122126 CNV deletion 24896259
nsv1074389 CNV deletion 25765185
esv3608532 CNV gain 21293372
esv3608531 CNV loss 21293372
esv3411275 CNV duplication 20981092
esv32635 CNV gain+loss 17666407
esv2759414 CNV gain+loss 17122850
esv2731791 CNV deletion 23290073
dgv1175e214 CNV gain 21293372
dgv1174e214 CNV gain 21293372

Additional Variant Information for PSORS1C3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PSORS1C3 Gene

Disorders for PSORS1C3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for PSORS1C3 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for PSORS1C3

genes like me logo Genes that share disorders with PSORS1C3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PSORS1C3 Gene

Publications for PSORS1C3 Gene

  1. Long noncoding RNA expression profile in fibroblast-like synoviocytes from patients with rheumatoid arthritis. (PMID: 27716329) Zhang Y … Li XJ (Arthritis research & therapy 2016) 2 3 58
  2. The major genetic determinants of HIV-1 control affect HLA class I peptide presentation. (PMID: 21051598) International HIV Controllers Study … Zhao M (Science (New York, N.Y.) 2010) 3 44 58
  3. Psoriasis vulgaris in Chinese individuals is associated with PSORS1C3 and CDSN genes. (PMID: 16965413) Chang YT … Tsai SF (The British journal of dermatology 2006) 3 44 58
  4. HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3. (PMID: 15848982) Holm SJ … O'Brien KP (Acta dermato-venereologica 2005) 3 44 58
  5. Methylomic profiling of cortex samples from completed suicide cases implicates a role for PSORS1C3 in major depression and suicide. (PMID: 28045465) Murphy TM … Mill J (Translational psychiatry 2017) 3 58

Products for PSORS1C3 Gene

Sources for PSORS1C3 Gene

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