Aliases for PSME3 Gene
Aliases for PSME3 Gene
- Proteasome Activator Subunit 3 2 3 5
- Proteasome (Prosome, Macropain) Activator Subunit 3 (PA28 Gamma; Ki) 2 3
- Activator Of Multicatalytic Protease Subunit 3 3 4
- Proteasome Activator 28 Subunit Gamma 3 4
- 11S Regulator Complex Subunit Gamma 3 4
- Ki Nuclear Autoantigen 3 4
- REG-GAMMA 3 4
- PA28gamma 3 4
- PA28G 3 4
- Proteasome Activator Complex Subunit 3 3
External Ids for PSME3 Gene
- HGNC: 9570
- Entrez Gene: 10197
- Ensembl: ENSG00000131467
- OMIM: 605129
- UniProtKB: P61289
Previous GeneCards Identifiers for PSME3 Gene
- GC17M040635
- GC17P043138
- GC17P040885
- GC17P041358
- GC17P038238
- GC17P040985
- GC17P036749
Summaries for PSME3 Gene
-
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
GeneCards Summary for PSME3 Gene
PSME3 (Proteasome Activator Subunit 3) is a Protein Coding gene. Among its related pathways are RET signaling and CDK-mediated phosphorylation and removal of Cdc6. Gene Ontology (GO) annotations related to this gene include identical protein binding and MDM2/MDM4 family protein binding. An important paralog of this gene is PSME1.
UniProtKB/Swiss-Prot for PSME3 Gene
-
Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).
Additional gene information for PSME3 Gene
- Monarch Initiative
- Search for PSME3 at DataMed
- Search for PSME3 at HumanCyc
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PSME3 Gene
Genomics for PSME3 Gene
GeneHancer (GH) Regulatory Elements for PSME3 Gene
Promoters and enhancers for PSME3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around PSME3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for PSME3 Gene
Genomic Locations for PSME3 Gene
- chr17:42,824,385-42,843,760
- (GRCh38/hg38)
- Size:
- 19,376 bases
- Orientation:
- Plus strand
- chr17:40,976,402-40,995,777
- (GRCh37/hg19)
Genomic View for PSME3 Gene
Genes around PSME3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q21.31 by Ensembl
- 17q21.31 by Entrez Gene
- 17q21.31 by HGNC
PSME3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PSME3 Gene
Proteins for PSME3 Gene
-
Protein details for PSME3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P61289-PSME3_HUMAN
- Recommended name:
- Proteasome activator complex subunit 3
- Protein Accession:
- P61289
- A8K9A3
- O35563
- P97373
- Q12920
- Q13172
- Q9BQD9
Protein attributes for PSME3 Gene
- Size:
- 254 amino acids
- Molecular mass:
- 29506 Da
- Quaternary structure:
-
- Homoheptamer; the stability of the heptamer is essential for the specific activation of the trypsine-like subunit and inhibition of the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits of the proteasome. Interacts with p53/TP53 and MDM2. Interacts with MAP3K3 (By similarity). Associates with the proteasome. Interacts with human cytomegalovirus UL27. Interacts with CCAR2.
Alternative splice isoforms for PSME3 Gene
- UniProtKB/Swiss-Prot:
Protein Expression for PSME3 Gene
Post-translational modifications for PSME3 Gene
- Acetylation at the major site Lys-195 is important for oligomerization and ability to degrade its target substrates. Deacetylated by SIRT1.
- Phosphorylated by MAP3K3 (By similarity). Phosphorylation at Ser-247 promotes its association with CCAR2.
- Ubiquitination at isoforms=214, Lys37, Lys100, Lys110, Lys121, and Lys195
Other Protein References for PSME3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for PSME3 (PSME3)
- Novus Biologicals Antibodies for PSME3
-
Abcam antibodies for PSME3
-
Cloud-Clone Corp. Antibodies for PSME3
- Invitrogen Antibodies for PSME3
- GeneTex PSME3 antibody for PSME3
-
Santa Cruz Biotechnology (SCBT) Antibodies for PSME3
- Sino Biological Antibodies for PSME3
Protein Products
- R&D Systems Proteins and Enzymes for PSME3 (PA28 Activator gamma Subunit)
-
OriGene Purified Proteins for PSME3
- Search Origene for MassSpec and Protein Over-expression Lysates for PSME3
- Origene Custom Protein Services for PSME3
- Sino Biological Recombinant Proteins for PSME3
- Browse Sino Biological Cell Lysates
- ProSpec Recombinant Proteins for PSME3
-
Cloud-Clone Corp. Proteins for PSME3
- Search GeneTex for Proteins for PSME3
-
ProSci Proteins for PSME3
-
Abcam proteins for PSME3
Assay Products
-
Cloud-Clone Corp. Assay Kits for PSME3
No data available for DME Specific Peptides for PSME3 Gene
Domains & Families for PSME3 Gene
Gene Families for PSME3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PSME3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PSME3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P61289UniProtKB/Swiss-Prot:
PSME3_HUMAN :- The C-terminal sequences affect heptamer stability and proteasome affinity.
- Belongs to the PA28 family.
- Domain:
-
- The C-terminal sequences affect heptamer stability and proteasome affinity.
- Family:
-
- Belongs to the PA28 family.
Function for PSME3 Gene
Molecular function for PSME3 Gene
- GENATLAS Biochemistry:
- proteasome (prosome,macropain) activator subunit 3 (PA28-gamma)
- UniProtKB/Swiss-Prot Function:
- Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regulation. Mediates CCAR2 and CHEK2-dependent SIRT1 inhibition (PubMed:25361978).
- UniProtKB/Swiss-Prot Induction:
- Up-regulated in thyroid carcinoma cells.
Phenotypes From GWAS Catalog for PSME3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002039 | p53 binding | IDA | 18309296 |
| GO:0005515 | protein binding | IPI | 12970408 |
| GO:0042802 | identical protein binding | IPI | 16169070 |
| GO:0061133 | endopeptidase activator activity | IDA | 18309296 |
| GO:0097371 | MDM2/MDM4 family protein binding | IDA | 18309296 |
Phenotypes for PSME3 Gene
- MGI mutant phenotypes for PSME3:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for PSME3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PSME3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for PSME3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PSME3 gene
- Search ViGene Biosciences for PSME3
CRISPR Products
-
OriGene CRISPR knockouts for PSME3
- genomics-online: gRNA clones - Search results for available PSME3 gene related products
- Applied Biological Materials CRISPR for PSME3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PSME3
- GenScript: Design CRISPR guide RNA sequences for PSME3
miRNA for PSME3 Gene
- miRTarBase miRNAs that target PSME3
-
- hsa-mir-7-5p (MIRT004063)
- hsa-mir-155-5p (MIRT020956)
- hsa-mir-124-3p (MIRT022991)
- hsa-mir-24-3p (MIRT030577)
- hsa-mir-16-5p (MIRT031898)
- hsa-let-7b-5p (MIRT032477)
- hsa-mir-484 (MIRT042151)
- hsa-mir-324-5p (MIRT043211)
- hsa-mir-331-3p (MIRT043475)
- hsa-mir-583 (MIRT077242)
- hsa-mir-548au-3p (MIRT251100)
- hsa-mir-539-5p (MIRT287286)
- hsa-mir-3117-5p (MIRT287289)
- hsa-mir-4311 (MIRT287291)
- hsa-mir-6758-5p (MIRT375623)
- hsa-mir-6856-5p (MIRT375624)
- hsa-mir-6734-5p (MIRT470135)
- hsa-mir-7111-5p (MIRT470136)
- hsa-mir-6870-5p (MIRT470137)
- hsa-mir-4723-5p (MIRT470138)
- hsa-mir-5698 (MIRT470139)
- hsa-mir-3175 (MIRT470140)
- hsa-mir-8085 (MIRT470141)
- hsa-mir-6731-5p (MIRT470142)
- hsa-mir-6878-5p (MIRT470143)
- hsa-mir-6797-5p (MIRT470144)
- hsa-mir-1249-5p (MIRT470145)
- hsa-mir-4644 (MIRT470146)
- hsa-mir-4306 (MIRT470147)
- hsa-mir-185-5p (MIRT470148)
- hsa-mir-6133 (MIRT470149)
- hsa-mir-6130 (MIRT470150)
- hsa-mir-6129 (MIRT470151)
- hsa-mir-6127 (MIRT470152)
- hsa-mir-4510 (MIRT470153)
- hsa-mir-4419a (MIRT470154)
- hsa-mir-570-3p (MIRT470155)
- hsa-mir-4459 (MIRT470156)
- hsa-mir-6794-5p (MIRT470157)
- hsa-mir-4716-3p (MIRT470158)
- hsa-mir-6760-5p (MIRT470159)
- hsa-mir-4779 (MIRT470160)
- hsa-mir-6768-5p (MIRT470161)
- hsa-mir-186-3p (MIRT564118)
- hsa-mir-5692a (MIRT564119)
- hsa-mir-1276 (MIRT564120)
- hsa-mir-7156-5p (MIRT711281)
- hsa-mir-4273 (MIRT711282)
- hsa-mir-519e-5p (MIRT711283)
- hsa-mir-515-5p (MIRT711284)
- hsa-mir-2117 (MIRT711285)
- hsa-mir-26b-3p (MIRT711286)
- hsa-mir-6861-5p (MIRT711287)
- hsa-mir-6862-3p (MIRT711288)
- hsa-mir-6784-3p (MIRT711289)
- hsa-mir-6742-3p (MIRT711290)
- hsa-mir-6791-5p (MIRT711291)
- hsa-mir-4292 (MIRT711292)
- hsa-mir-3620-3p (MIRT711293)
- hsa-mir-6865-3p (MIRT711294)
- hsa-mir-504-5p (MIRT711295)
- hsa-mir-6750-3p (MIRT711296)
- hsa-mir-425-3p (MIRT724085)
- hsa-mir-1206 (MIRT724086)
- hsa-mir-503-3p (MIRT724087)
- hsa-mir-34c-3p (MIRT724088)
- hsa-mir-32-5p (MIRT726845)
- hsa-mir-92b-3p (MIRT726846)
- hsa-mir-92a-3p (MIRT726847)
- hsa-mir-1273h-5p (MIRT736891)
- hsa-mir-1322 (MIRT737383)
- hsa-mir-139-5p (MIRT737560)
- hsa-mir-30b-3p (MIRT739781)
- hsa-mir-30c-1-3p (MIRT739834)
- hsa-mir-30c-2-3p (MIRT739877)
- hsa-mir-3662 (MIRT741997)
- hsa-mir-3689a-3p (MIRT742283)
- hsa-mir-3689b-3p (MIRT742353)
- hsa-mir-3689c (MIRT742423)
- hsa-mir-4684-5p (MIRT746949)
- hsa-mir-548c-3p (MIRT750678)
- hsa-mir-6779-5p (MIRT755525)
- hsa-mir-6780a-5p (MIRT755598)
- hsa-mir-6788-5p (MIRT755986)
- hsa-mir-887-5p (MIRT760413)
miRNA Products
- Search ViGene Biosciences for PSME3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PSME3
- Browse OriGene Inhibitory RNA Products For PSME3
- genomics-online: shRNA clones - Search results for available PSME3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PSME3 gene
Clone Products
- Sino Biological Human cDNA Clone for PSME3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PSME3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PSME3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PSME3 gene related products
- orf clones - Search results for available PSME3 gene related products
- Applied Biological Materials Clones for PSME3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for PSME3
-
ViGene Biosciences adenoviral particle packaged cDNA for PSME3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for PSME3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for PSME3 gene
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PSME3 Gene
Localization for PSME3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PSME3 Gene
- Nucleus. Cytoplasm. Note=Localizes to the cytoplasm during mitosis following nuclear envelope breakdown at this distinct stage of the cell cycle which allows its interaction with MAP3K3 kinase. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| mitochondrion | 1 |
- Nucleoplasm (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000502 | proteasome complex | TAS | 8811196 |
| GO:0005634 | nucleus | IEA,HDA | 21630459 |
| GO:0005654 | nucleoplasm | IDA,TAS | -- |
| GO:0005737 | cytoplasm | IBA | -- |
| GO:0005829 | cytosol | TAS,IDA | -- |
Pathways & Interactions for PSME3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 |
.93
.93
|
.80
.78
.78
.70
.47
.31
|
| 2 | RET signaling |
.92
|
.92
|
| 3 | HIV Life Cycle |
.65
|
.45
|
| 4 | Class I MHC mediated antigen processing and presentation | ||
| 5 | Antigen processing-Cross presentation | ||
Pathways by source for PSME3 Gene
1 BioSystems pathway for PSME3 Gene
3 KEGG pathways for PSME3 Gene
1 GeneGo (Thomson Reuters) pathway for PSME3 Gene
Interacting Proteins for PSME3 Gene
Selected Interacting proteins:
ENSP00000293362
P61289-PSME3_HUMAN
for PSME3 Gene via
STRING
MINT
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0000209 | protein polyubiquitination | TAS | -- |
| GO:0002223 | stimulatory C-type lectin receptor signaling pathway | TAS | -- |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | TAS | -- |
| GO:0006521 | regulation of cellular amino acid metabolic process | TAS | -- |
No data available for SIGNOR curated interactions for PSME3 Gene
Drugs & Compounds for PSME3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Bortezomib | Approved, Investigational | Pharma | inhibitor, other | Proteosome and NF-kappaB inhibitor, Other, Proteasome inhibitors | 826 | |
| carfilzomib | Approved, Investigational | Pharma | other, Inhibitor | Other, 20S Proteasome Inhibitor | 0 | |
| AM 114 | Pharma | 20S proteasome inhibitor | 0 | |||
| CEP-18770 | Pharma | Proteasome inhibitor | 0 | |||
| MLN9708 | Pharma | Proteasome inhibitor, 20S Proteasome Inhibitor | 0 |
(3) ApexBio Compounds for PSME3 Gene
Transcripts for PSME3 Gene
mRNA/cDNA for PSME3 Gene
- (5) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (626) Selected AceView cDNA sequences:
- (17) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for PSME3 Gene
- Proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki):
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for PSME3
- genomics-online: gRNA clones - Search results for available PSME3 gene related products
- Applied Biological Materials CRISPR for PSME3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PSME3
- GenScript: Design CRISPR guide RNA sequences for PSME3
miRNA Products
- Search ViGene Biosciences for PSME3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for PSME3
- Browse OriGene Inhibitory RNA Products For PSME3
- genomics-online: shRNA clones - Search results for available PSME3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for PSME3 gene
Clone Products
- Sino Biological Human cDNA Clone for PSME3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for PSME3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PSME3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available PSME3 gene related products
- orf clones - Search results for available PSME3 gene related products
- Applied Biological Materials Clones for PSME3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | · | 12c | · | 12d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||
| SP4: | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP8: | - | ||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||||||||||
| SP11: |
Expression for PSME3 Gene
This gene is overexpressed in Bone (13.9) and Peripheral blood mononuclear cells (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PSME3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PSME3 Gene:
PSME3SOURCE GeneReport for Unigene cluster for PSME3 Gene:
Hs.152978Evidence on tissue expression from TISSUES for PSME3 Gene
- Nervous system(5)
- Lung(4.6)
- Intestine(3.6)
- Skin(3.4)
- Eye(2.5)
- Kidney(2.3)
- Thyroid gland(2.3)
- Liver(2)
Primer Products
-
OriGene qPCR primer pairs for PSME3
-
OriGene qPCR primer pairs and template standards for PSME3
- genomics-online: primer clones - Search results for available PSME3 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PSME3 Gene
Orthologs for PSME3 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PSME3 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | PSME3 33 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Psme3 33 |
|
||
| dog (Canis familiaris) |
Mammalia | PSME3 33 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Psme3 33 16 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | PSME3 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | PSME3 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
OneToMany | |
| -- 34 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | psme3 33 |
|
||
| Str.3210 33 |
|
||||
| zebrafish (Danio rerio) |
Actinopterygii | psme3 33 34 |
|
||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10191 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | REG 35 33 34 |
|