Aliases for PSMC6 Gene
Aliases for PSMC6 Gene
External Ids for PSMC6 Gene
- HGNC: 9553
- Entrez Gene: 5706
- Ensembl: ENSG00000100519
- OMIM: 602708
- UniProtKB: P62333
Previous GeneCards Identifiers for PSMC6 Gene
- GC14P050496
- GC14P046969
- GC14P051163
- GC14P052243
- GC14P053173
- GC14P033334
Summaries for PSMC6 Gene
-
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, Jul 2008]
GeneCards Summary for PSMC6 Gene
PSMC6 (Proteasome 26S Subunit, ATPase 6) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and RET signaling. Gene Ontology (GO) annotations related to this gene include hydrolase activity and protein binding, bridging.
UniProtKB/Swiss-Prot for PSMC6 Gene
-
Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PSMC6 Gene
Genomics for PSMC6 Gene
GeneHancer (GH) Regulatory Elements for PSMC6 Gene
Promoters and enhancers for PSMC6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around PSMC6 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the PSMC6 gene promoter:
-
- MEF-2A
- aMEF-2
- AREB6
- HNF-4alpha1
- AhR
- HNF-4alpha2
- GATA-1
- Pax-5
- LCR-F1
- Bach2
Regulatory Element Products
Genomic Locations for PSMC6 Gene
Genomic Locations for PSMC6 Gene
- chr14:52,707,163-52,728,587
- (GRCh38/hg38)
- Size:
- 21,425 bases
- Orientation:
- Plus strand
- chr14:53,173,890-53,195,305
- (GRCh37/hg19)
- Size:
- 21,416 bases
- Orientation:
- Plus strand
Genomic View for PSMC6 Gene
Genes around PSMC6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q22.1 by Entrez Gene
- 14q22.1 by HGNC
- 14q22.1 by Ensembl
PSMC6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PSMC6 Gene
Proteins for PSMC6 Gene
-
Protein details for PSMC6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P62333-PRS10_HUMAN
- Recommended name:
- 26S proteasome regulatory subunit 10B
- Protein Accession:
- P62333
- B2R975
- P49719
- Q6IBU3
- Q92524
Protein attributes for PSMC6 Gene
- Size:
- 389 amino acids
- Molecular mass:
- 44173 Da
- Quaternary structure:
-
- Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits, a base containing 6 ATPases including PSMC6 and few additional components (PubMed:27428775, PubMed:27342858). Interacts with PAAF1 (PubMed:15831487).
Protein Expression for PSMC6 Gene
Post-translational modifications for PSMC6 Gene
Other Protein References for PSMC6 Gene
Antibody Products
- Novus Biologicals Antibodies for PSMC6
-
Abcam antibodies for PSMC6
- Invitrogen Antibodies for PSMC6
- GeneTex PSMC6 Antibody for PSMC6
-
Boster Bio Antibodies for PSMC6
-
Santa Cruz Biotechnology (SCBT) Antibodies for PSMC6
Protein Products
-
OriGene Purified Proteins for PSMC6
- Search Origene for MassSpec and Protein Over-expression Lysates for PSMC6
- Origene Custom Protein Services for PSMC6
- GeneTex Proteins for PSMC6
-
ProSci Proteins for PSMC6
-
Abcam proteins for PSMC6
Assay Products
No data available for DME Specific Peptides for PSMC6 Gene
Domains & Families for PSMC6 Gene
Gene Families for PSMC6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for PSMC6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for PSMC6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P62333- Family:
-
- Belongs to the AAA ATPase family.
Function for PSMC6 Gene
Molecular function for PSMC6 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
- GENATLAS Biochemistry:
- multicatalytic proteinase complex (prosome,macropain,26kDa) 19/22S regulator of proteasome p42,ATPase subunit,44kDa
Phenotypes From GWAS Catalog for PSMC6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 16189514 |
| GO:0005524 | ATP binding | IEA | -- |
| GO:0016787 | hydrolase activity | IEA | -- |
| GO:0016887 | ATPase activity | TAS | 9464850 |
Phenotypes for PSMC6 Gene
- GenomeRNAi human phenotypes for PSMC6:
-
- Increased shRNA abundance (Z-score > 2)
- G0/1 arrest
- Increased G1 DNA content
- Decreased shRNA abundance (Z-score < -2)
- Decreased viability of wild-type and TP53 knockout cells, decreased TP53 protein expression ratio (wild-type / TP53 knockout cells)
- Reduced mammosphere formation
- Decreased ionizing radiation sensitivity
- Decreased shRNA abundance
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Downregulation of NFkappaB pathway
- Decreased hepcidin::fluc mRNA expression
- Decreased NF-kappaB reporter expression
- Decreased influenza A/WSN/33 replication
- Increased viability
- Synthetic lethal with MLN4924 (a NAE inhibitor)
- FOXO1 nuclear localization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PSMC6
-
CRISPR Products
-
OriGene CRISPR knockouts for PSMC6
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- Applied Biological Materials CRISPR for PSMC6
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PSMC6
- GenScript: Design CRISPR guide RNA sequences for PSMC6
miRNA for PSMC6 Gene
- miRTarBase miRNAs that target PSMC6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PSMC6
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PSMC6
- genomics-online: shRNA clones - Search results for available PSMC6 gene related products
Clone Products
- Sino Biological Human cDNA Clone for PSMC6
- VectorBuilder custom plasmid, inducible vectors for PSMC6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PSMC6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PSMC6
- genomics-online: cdna clones - Search results for available PSMC6 gene related products
- orf clones - Search results for available PSMC6 gene related products
- Applied Biological Materials Clones for PSMC6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PSMC6 Gene
Localization for PSMC6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PSMC6 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 3 |
| cytoskeleton | 2 |
| peroxisome | 2 |
- Cytosol (2)
- Nucleoplasm (2)
- Plasma membrane (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000502 | proteasome complex | IDA,IEA | 9464850 |
| GO:0005634 | nucleus | IEA,IDA | 10419517 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for PSMC6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | CDK-mediated phosphorylation and removal of Cdc6 |
.93
.93
|
.80
.78
.78
.70
.47
.31
|
| 2 | RET signaling |
.92
|
.92
|
| 3 | Chks in Checkpoint Regulation | ||
| 4 | HIV Life Cycle |
.64
|
.45
|
| 5 | Class I MHC mediated antigen processing and presentation | ||
Pathways by source for PSMC6 Gene
1 Sino Biological pathway for PSMC6 Gene
2 BioSystems pathways for PSMC6 Gene
2 KEGG pathways for PSMC6 Gene
3 GeneGo (Thomson Reuters) pathways for PSMC6 Gene
19 Qiagen pathways for PSMC6 Gene
Interacting Proteins for PSMC6 Gene
Selected Interacting proteins:
P62333-PRS10_HUMAN
ENSP00000401802
for PSMC6 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for PSMC6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0000209 | protein polyubiquitination | TAS | -- |
| GO:0002223 | stimulatory C-type lectin receptor signaling pathway | TAS | -- |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | TAS | -- |
| GO:0006511 | ubiquitin-dependent protein catabolic process | IC | 9464850 |
No data available for SIGNOR curated interactions for PSMC6 Gene
Drugs & Compounds for PSMC6 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for PSMC6 Gene
mRNA/cDNA for PSMC6 Gene
- (2) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (475) Selected AceView cDNA sequences:
- (19) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000445930 2188 bps (uc010tqx.3)
- ENST00000555887 573 bps (uc059bok.1)
- ENST00000458604 1093 bps (uc059bom.1)
- ENST00000557240 625 bps (uc059bon.1)
- ENST00000554956 535 bps (uc059boo.1)
Unigene Clusters for PSMC6 Gene
- Proteasome (prosome, macropain) 26S subunit, ATPase, 6:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for PSMC6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PSMC6
- genomics-online: gRNA clones - Search results for available PSMC6 gene related products
- Applied Biological Materials CRISPR for PSMC6
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for PSMC6
- GenScript: Design CRISPR guide RNA sequences for PSMC6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for PSMC6
- Browse OriGene Inhibitory RNA Products For PSMC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PSMC6
- genomics-online: shRNA clones - Search results for available PSMC6 gene related products
Clone Products
- Sino Biological Human cDNA Clone for PSMC6
- VectorBuilder custom plasmid, inducible vectors for PSMC6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PSMC6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PSMC6
- genomics-online: cdna clones - Search results for available PSMC6 gene related products
- orf clones - Search results for available PSMC6 gene related products
- Applied Biological Materials Clones for PSMC6
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for PSMC6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Peripheral blood mononuclear cells (7.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for PSMC6 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of PSMC6 Gene:
PSMC6SOURCE GeneReport for Unigene cluster for PSMC6 Gene:
Hs.156171Evidence on tissue expression from TISSUES for PSMC6 Gene
- Nervous system(4.8)
- Liver(4.6)
- Muscle(3.3)
- Heart(3.1)
- Kidney(2.8)
- Lung(2.5)
- Adrenal gland(2.4)
- Blood(2.3)
- Intestine(2.2)
- Eye(2.1)
- Skin(2)
Primer Products
-
OriGene qPCR primer pairs and template standards for PSMC6
-
OriGene qPCR primer pairs for PSMC6
- genomics-online: primer clones - Search results for available PSMC6 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PSMC6 Gene
Orthologs for PSMC6 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | PSMC6 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | PSMC6 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | PSMC6 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | PSMC6 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | PSMC6 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Psmc6 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Psmc6 33 |
|
||
| chicken (Gallus gallus) |
Aves | PSMC6 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | PSMC6 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | psmc6 33 |
|
||
| MGC76159 33 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.3381 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | psmc6 34 33 |
|
OneToOne | |
| Dr.29047 33 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.8441 33 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | CG7257 35 |
|
|
|
| Rpt4R 34 |
|
OneToMany | |||
| Rpt4 34 35 33 |
|
OneToMany | |||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001407 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | rpt-4 34 33 |
|
OneToOne | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | RPT4 34 33 |
|
OneToOne | |
| K. lactis yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0C09592g 33 |
|
||
| A. gosspyii yeast (Ashbya gossypii) |
Saccharomycetes | AGOS_AAL113W 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | RPT4A 33 |
|
||
| Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.5748 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os02g0199900 33 |
|
||
| Os.292 33 |
|
||||
| barley (Hordeum vulgare) |
Liliopsida | Hv.5889 33 |
|
||
| corn (Zea mays) |
Liliopsida | Zm.3972 33 |
|
||
| wheat (Triticum aestivum) |
Liliopsida | Ta.14349 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.3434 34 |
|
OneToOne | |
| Cin.11771 33 |
|
||||
| fission yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | rpt4 33 |
|
||
| bread mold (Neurospora crassa) |
Ascomycetes | NCU07367 33 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.11771 33 |
|
- Species where no ortholog for PSMC6 was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Evolution for PSMC6 Gene
- ENSEMBL:
- Gene Tree for PSMC6 (if available)
- TreeFam:
- Gene Tree for PSMC6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for PSMC6: view image
Paralogs for PSMC6 Gene
(24) SIMAP similar genes for PSMC6 Gene using alignment to 9 proteins:
- PRS10_HUMAN
- H0YJC0_HUMAN
- H0YJD2_HUMAN
- H0YJE9_HUMAN
- H0YJS8_HUMAN
- H0YJT1_HUMAN
- H0YJW2_HUMAN
- H0YJX2_HUMAN
- H0YJY8_HUMAN
Pseudogenes.org Pseudogenes for PSMC6 Gene
No data available for Paralogs for PSMC6 Gene
Variants for PSMC6 Gene
| SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000031124 | -- | 52,705,178(+) | G/A | upstream_transcript_variant | |
| rs1000077396 | -- | 52,710,716(+) | G/A | 5_prime_UTR_variant, intron_variant | |
| rs1000367724 | -- | 52,717,302(+) | T/C | intron_variant | |
| rs1000402885 | -- | 52,725,205(+) | G/C | intron_variant | |
| rs1000424289 | -- | 52,724,540(+) | A/G | intron_variant |
Residual Variation Intolerance Score:
25% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.38;
8.34% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for PSMC6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PSMC6
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PSMC6 Gene
Disorders for PSMC6 Gene
Additional Disease Information for PSMC6
No disorders were found for PSMC6 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PSMC6 Gene
Publications for PSMC6 Gene
- Chromosomal localization and immunological analysis of a family of human 26S proteasomal ATPases. (PMID: 9473509) Tanahashi N … Tanaka K (Biochemical and biophysical research communications 1998) 2 3 22 58
- cDNA cloning of p42, a shared subunit of two proteasome regulatory proteins, reveals a novel member of the AAA protein family. (PMID: 8674546) Fujiwara T … DeMartino GN (FEBS letters 1996) 2 3 4 58
- Mass spectrometric characterization of the affinity-purified human 26S proteasome complex. (PMID: 17323924) Wang X … Huang L (Biochemistry 2007) 3 4 58
- Proteasomal ATPase-associated factor 1 negatively regulates proteasome activity by interacting with proteasomal ATPases. (PMID: 15831487) Park Y … Yoon JB (Molecular and cellular biology 2005) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
Products for PSMC6 Gene
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- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Cyagen custom Knockout/knockin (KOKI) mouse models for PSMC6
- VectorBuilder custom plasmid, inducible vectors for PSMC6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PSMC6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 60 available PSMC6 Antibodies ranked by validation data
- Compare Top PSMC6 Antibodies
- antibodies-online: Search results for available PSMC6 related products ranked by validation data
- antibodies-online: Search results for 10 available PSMC6 Proteins ranked by validation data
- Compare Top PSMC6 Proteins
- GeneTex PSMC6 Antibody for PSMC6
- GeneTex Proteins for PSMC6
- Santa Cruz Biotechnology (SCBT) Antibodies for PSMC6
- Search Santa Cruz Biotechnology (SCBT) for PSMC6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for PSMC6
- genomics-online: cdna clones - Search results for available PSMC6 gene related products
- orf clones - Search results for available PSMC6 gene related products
- genomics-online: gRNA clones - Search results for available PSMC6 gene related products
- genomics-online: primer clones - Search results for available PSMC6 gene related products
- genomics-online: shRNA clones - Search results for available PSMC6 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for PSMC6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for PSMC6
- GeneCopoeia miRNA 3'UTR Target clone products for PSMC6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for PSMC6
- Boster Bio Antibodies for PSMC6
- Browse Boster Bio ELISA Kits
Sources for PSMC6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt