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PSD3 (Pleckstrin And Sec7 Domain Containing 3) is a Protein Coding gene. Diseases associated with PSD3 include Hepatocellular Carcinoma. Among its related pathways are Endocytosis. Gene Ontology (GO) annotations related to this gene include phospholipid binding and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is PSD.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005085 | guanyl-nucleotide exchange factor activity | IEA | -- |
GO:0005086 | ARF guanyl-nucleotide exchange factor activity | IBA | 21873635 |
GO:0005515 | protein binding | IEA | -- |
GO:0005543 | phospholipid binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005886 | plasma membrane | IEA | -- |
GO:0014069 | postsynaptic density | IEA | -- |
GO:0016020 | membrane | IEA | -- |
GO:0030054 | cell junction | IEA | -- |
GO:0032587 | ruffle membrane | IBA,ISS | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Endocytosis |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0032012 | regulation of ARF protein signal transduction | IEA | -- |
ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP3: | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP9: |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | PSD3 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Psd3 30 17 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | PSD3 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Rat (Rattus norvegicus) |
Mammalia | Psd3 30 |
|
||
Cow (Bos Taurus) |
Mammalia | PSD3 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
-- 31 |
|
OneToMany | |||
Chicken (Gallus gallus) |
Aves | PSD3 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | PSD3 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | psd3 30 |
|
||
Str.16491 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | psd3l 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | Efa6 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | efa-6 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | GEA2 31 |
|
ManyToMany | |
GEA1 31 |
|
ManyToMany | |||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
713792 | Likely Benign: not provided | 18,872,526(-) | T/A | MISSENSE_VARIANT | |
719443 | Benign: not provided | 18,556,275(-) | G/A | SYNONYMOUS_VARIANT | |
719804 | Likely Benign: not provided | 18,872,552(-) | G/A | SYNONYMOUS_VARIANT | |
726772 | Benign: not provided | 18,867,714(-) | T/G | MISSENSE_VARIANT | |
731606 | Benign: not provided | 18,872,192(-) | G/C | MISSENSE_VARIANT |
Disorder | Aliases | PubMed IDs |
---|---|---|
hepatocellular carcinoma |
|
|