Aliases for PSD Gene
External Ids for PSD Gene
Previous GeneCards Identifiers for PSD Gene
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
GeneCards Summary for PSD Gene
PSD (Pleckstrin And Sec7 Domain Containing) is a Protein Coding gene. Diseases associated with PSD include Cone-Rod Dystrophy 1 and Branch Retinal Artery Occlusion. Among its related pathways are Endocytosis. Gene Ontology (GO) annotations related to this gene include obsolete signal transducer activity and ARF guanyl-nucleotide exchange factor activity. An important paralog of this gene is PSD2.
UniProtKB/Swiss-Prot Summary for PSD Gene
Guanine nucleotide exchange factor for ARF6 (PubMed:23603394). Induces cytoskeletal remodeling (By similarity).