Aliases for PRXL2A Gene
External Ids for PRXL2A Gene
Previous HGNC Symbols for PRXL2A Gene
Previous GeneCards Identifiers for PRXL2A Gene
GeneCards Summary for PRXL2A Gene
PRXL2A (Peroxiredoxin Like 2A) is a Protein Coding gene.
UniProtKB/Swiss-Prot for PRXL2A Gene
Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880).